Liver-protecting medicine or health-care product composition as well as preparation method and use thereof

The technology of a health care product and a composition is applied in the field of liver protection medicine or health care product composition and its preparation and use, which can solve the problems of homology of medicine and food, and achieves alleviation of liver damage, good commercial application prospect and good appearance. Effect

Active Publication Date: 2013-08-28
SICHUAN JIUZHANG BIO TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, dozens of drugs have been reported to have anti-hepatic damage, such as Cordyceps, rhubarb, Panax notoginseng, Astragalus, Sophora flavescens, Salvia miltiorrhiza, Lycium barbarum, Schisandra chinensis, Ganoderma lucidum, purslane, Jiaogulan, Chuanxiong, etc. Traditional Chinese medicinal materials

Method used

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  • Liver-protecting medicine or health-care product composition as well as preparation method and use thereof
  • Liver-protecting medicine or health-care product composition as well as preparation method and use thereof
  • Liver-protecting medicine or health-care product composition as well as preparation method and use thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0054] The preparation of embodiment 1 medicine of the present invention or health product composition

[0055] First take 100g of β-cyclodextrin and 60% V / V ethanol and grind them evenly at a ratio of 1:1, then add 100g of broken Ganoderma lucidum spore powder and grind thoroughly, and dry the ground clathrate at 60°C and -0.08MP for 4 hours. Then mix the above-mentioned clathrate of Ganoderma lucidum spore powder with 230g honeysuckle extract, 300g Eucommia leaf extract, 70g chrysanthemum extract, and add 225g mannitol, 225g lactose, 30g hydroxypropyl cellulose, 5g aspartame After mixing evenly, take 10g of povidone K30 and dissolve it in 90% edible alcohol to make a 5% (W / V) solution as an adhesive to prepare a soft material, and place the prepared soft material in a constant temperature drying oven at 60°C Dry until the moisture content is 3%, pass through a 20-mesh sieve for granulation to obtain dried granules, mix in 5g of magnesium stearate, and tablet to obtain 1000 t...

Embodiment 2

[0086] Embodiment 2 The preparation of medicine or health product composition of the present invention

[0087] Get Eucommia leaf extract 100g, honeysuckle extract 345g, chrysanthemum flower extract 280g, broken Ganoderma lucidum spore powder 100g. After mixing, add appropriate amount of dextrin and soluble starch, and wet granulate to obtain granules.

Embodiment 3

[0088] Embodiment 3 The preparation of medicament or health food composition of the present invention

[0089] Take 200g of eucommia leaf extract, 115g of honeysuckle extract, 35g of chrysanthemum flower extract, 25g of broken ganoderma lucidum spore powder, add appropriate amount of microcrystalline cellulose, mix well, pack into capsules, and obtain capsules.

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Abstract

The invention provides a liver-protecting medicine or a health-care product composition, which is a chewable tablet prepared from the following materials in parts by weight: 100-200 parts of folium cortex eucommiae extract, 115-345 parts of honeysuckle extract, 25-100 parts of reishi shell-broken spore powder, 35-280 parts of chrysanthemum extract, 25-100 parts of beta-cyclodextrin, 130-705 parts of filler, 11-39 parts of a disintegrating agent, 1.8-6.5 parts of a binder, 0.9-3.5 parts of a flavoring agent, and 0.8-14.5 parts of a lubricating agent. The medicine or the health-care product composition disclosed by the invention plays a role of synergistic interaction after four materials of folium cortex eucommiae are used in compatibility, can effectively reduce an injury of alcohol on the liver, and reduces steatotic hepatocyte; the composition is safe and nontoxic; and a new choice is provided for the liver-protecting medicine or the health-care product. The chewable tablet prepared by the preparation method is good in mouthfeel and appearance, and has a good commercial application prospect; the compliance is improved; and the range of users is also expanded.

Description

[0001] This application is a divisional application of the patent application with application number: 201110386854.4. Original application number: 201110386854.4, application date: November 28, 2011, invention name: a hepatoprotective drug or health product composition and its preparation method and application. technical field [0002] The invention relates to a hepatoprotective drug or health product composition, a preparation method and application thereof. Background technique [0003] The occurrence of chemical liver injury is related to the daily exposure to chemical poisons, alcohol and some drugs, and these factors are likely to cause damage to liver function. There are some substances that are toxic to the liver in both nature and human industrial production, which are called "liver-friendly poisons". These poisons are generally susceptible to the human population and have a short incubation period. Different degrees of liver cell necrosis, steatosis, cirrhosis an...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/46A61K9/20A61P1/16A23L1/29A23L33/00
Inventor 张洁黄英杨华蓉梁贵伦黄望严永江田晨煦张欣
Owner SICHUAN JIUZHANG BIO TECH CO LTD
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