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Antibiosis gel for curing cervical and vaginal diseases of gynaecology

A vaginal disease, gel technology, applied in the field of external medicine, can solve the problems of poor treatment effect, poor bactericidal effect, skin allergies, etc., and achieve the effect of no toxic side effects, small vaginal irritation, and strong antibacterial effect

Active Publication Date: 2015-04-22
WUHAN LANGQI BIOLOGICAL SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The treatment of gynecological cervical and vaginal diseases is preferably topical medication, but the existing external vaginal medications have poor bactericidal effect, strong irritation, skin allergies, easy to repeat, and poor therapeutic effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] The antibacterial gel for treating gynecological cervix and vaginal diseases per 100 grams of the present embodiment is made of the raw materials of the following weight ratio: chitosan 0.5g, tea tree essential oil 4g, borneol 0.5g, borax 0.5g, carbomer 0.5 g, 6 g of ethanol, and the balance is pure water.

[0025] Its preparation method comprises the following steps:

[0026] a. Evenly disperse the carbomer in pure water and soak it until fully dissolved to obtain a phase A solution;

[0027] b. dissolving chitosan in purified water to obtain phase B solution;

[0028] c. Dissolve the borneol in ethanol and completely dissolve it, add tea tree essential oil and stir evenly to obtain a phase C solution;

[0029] d. Dissolve borax in the remaining pure water, stir and dissolve to obtain phase D solution;

[0030] Mix all the four-phase solutions A, B, C and D, and stir for 30 minutes to obtain.

Embodiment 2

[0032] Every 100 grams of the antibacterial gel for the treatment of gynecological cervix and vaginal diseases of the present embodiment is made from the raw materials of the following weight ratio: chitosan 1g, tea tree essential oil 3g, borneol 2g, borax 1g, carbomer 0.8g, ethanol 8g, and the balance is purified water.

[0033] Its preparation method is as embodiment 1.

Embodiment 3

[0035] The antibacterial gel for treating gynecological cervix and vaginal diseases per 100 grams of the present embodiment is made from the raw materials of following weight ratio: chitosan 1g, tea tree essential oil 5g, borneol 3g, borax 2g, carbomer 2g, ethanol 10g , The balance is purified water.

[0036] Its preparation method is as embodiment 1.

[0037] The antibacterial gel for the treatment of gynecological cervical and vaginal diseases prepared in Examples 1 to 3 of the present invention was subjected to a bacteriostatic effect experiment, and the experimental results are shown in Table 1.

[0038] Table 1 Antibacterial effect

[0039] project

Action time (min)

Antibacterial rate, %

Escherichia coli (8099)

5

≥98

Staphylococcus aureus (ATCC 6538)

5

≥95

Candida albicans (ATCC 10231)

5

≥96

[0040] According to the evaluation criteria stipulated in Appendix C4 of GB15979-2002, the antibacterial rate...

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PUM

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Abstract

The invention discloses an antibiosis gel for curing cervical and vaginal diseases of gynaecology. Each 100 grams of gel is composed of following raw materials: 0.1 to 1 gram of chitosan, 0.1 to 5 grams of tea tree essential oil, 0.1 to 3 grams of borneol, 0.1 to 2 grams of borax, 0.25 to 2 grams of carbomer, 4 to 10 grams of ethanol and the balance of purified water. The antibiosis gel for curing cervical and vaginal diseases of gynaecology has a bacteriostasis rate not smaller than 90%, and has a strong bacteriostatic action. The antibiosis gel has a good biocompatibility, has cytotoxicity smaller than 2 grades, generates little stimulation to vagina, and does not have delayed type hypersensitivity. Each detection parameter of the antibiosis gel meets the corresponding national criterions or regulations. The antibiosis gel is safe during the using process, is capable of satisfying the needs of clinical application, and has the advantages of safety, high-efficiency, no side or toxic effect, and user-friendliness.

Description

technical field [0001] The invention relates to external medicine, in particular to an antibacterial gel for treating gynecological cervical and vaginal diseases. Background technique [0002] According to the incomplete statistics of the World Health Organization, the incidence of various gynecological diseases among women is above 65%. With the development of society and the continuous change of people's lifestyle and behavior, the prevalence of reproductive tract infections, menstrual disorders and breast diseases is gradually increasing. Gynecological infectious diseases are a class of common diseases and frequently-occurring diseases, especially fungal vaginitis, cervical erosion and senile vaginitis incidence rate is very high. [0003] In the epidemiological survey results of common gynecological diseases, the order of the prevalence of reproductive tract infections is as follows: chronic cervicitis 39.3%, vaginitis caused by various causes 15.9%, genital Chlamydia t...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/61A61K9/06A61P31/02A61P15/00A61P15/02A61K31/045A61K33/22A61K31/722
Inventor 李燃
Owner WUHAN LANGQI BIOLOGICAL SCI & TECH