Compound medicine for treating hypoferric anemia and preparation method thereof
An iron-deficiency anemia, compound technology, applied in drug delivery, drug combination, medical preparations containing active ingredients, etc., can solve problems such as iron malabsorption, achieve long-lasting effect, consolidated curative effect, and no rebound effect
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Embodiment 1
[0027] Embodiment 1: The preparation method of the compound medicine for the treatment of iron deficiency anemia comprises the following steps,
[0028] 1) Pre-treatment: ① Grind jujube, saponin, rehmannia glutinosa, hawthorn, and rehmannia glutinosa, and pass through a 60-mesh sieve; ② add sodium carboxymethyl starch to purified water to make 10% sodium starch glycolate slurry;
[0029] 2) Mixing: jujube 150-200, saponin 80-300, rehmannia 37-41, astragalus 70-85, hawthorn 35-50, cork 99-121, scutellaria 76-83, ferrous fumarate 3-50 5. Sucrose 67-86, dextrin 35-65, microcrystalline cellulose 90-110, sodium starch glycolate 58-71, copovidone 54-66, silicon dioxide 21-26, magnesium stearate 9-11 Put the above-mentioned components in a mixer and mix them for 10-20 minutes;
[0030] 3) Granulation: add an appropriate amount of 10% carboxymethyl starch sodium slurry to make soft materials, and then use a 12-mesh screen to make granules;
[0031] 4) Drying: Use a fluidized bed for...
Embodiment 2
[0037] Embodiment 2: Take 150-200 pieces of jujube, 80-300 pieces of saponin, 37-41 pieces of rehmannia root, 70-85 pieces of astragalus, 35-50 pieces of hawthorn, 99-121 pieces of cork phellodendron, 76-83 pieces of baicalin, and 3-30 pieces of ferrous fumarate. 5. Sucrose 67-86, dextrin 35-65, microcrystalline cellulose 90-110, sodium starch glycolate 58-71, copovidone 54-66, silicon dioxide 21-26, magnesium stearate 9-11 Carry out pretreatment; Get hypromellose 12.6~15.4, talcum powder 3.6~4.4, triacetin 1.8~2.2 to make coating agent; Its preparation method is as described in Example 1, abbreviated, according to Example 1 Preparation method, namely the compound drug B for the treatment of iron deficiency anemia.
Embodiment 3
[0038]Embodiment 3: Take 150-200 pieces of jujube, 80-300 pieces of saponin, 37-41 pieces of rehmannia root, 70-85 pieces of astragalus, 35-50 pieces of hawthorn, 99-121 pieces of Phellodendron cortex, 76-83 pieces of baicalin, and 3-30 pieces of ferrous fumarate. 5. Sucrose 67-86, dextrin 35-65, microcrystalline cellulose 90-110, sodium starch glycolate 58-71, copovidone 54-66, silicon dioxide 21-26, magnesium stearate 9-11 Carry out pretreatment; Get hypromellose 12.6~15.4, talcum powder 3.6~4.4, triacetin 1.8~2.2 to make coating agent; Its preparation method is as described in Example 1, abbreviated, according to Example 1 Preparation method, namely the compound drug C for the treatment of iron deficiency anemia.
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