A kind of konjac polypeptide extract, preparation method and application thereof

An extract, konjac technology, applied in the field of medicine and biology, can solve the problems of lowering blood sugar, no konjac flying powder diabetes, unable to control blood sugar, etc., and achieves the effects of less toxic side effects and wide application.
CN103436582BActive Publication Date: 2015-12-23瀚坤食品(深圳)有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
瀚坤食品(深圳)有限公司
Publication Date
2015-12-23

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Abstract

The invention belongs to the field of medical biology, and specifically relates to a method for extracting konjac polypeptide extract from konjac powder, and the konjac polypeptide extract obtained by the method and the application of the konjac polypeptide extract. In order to increase the content of konjac polypeptide in the konjac polypeptide extract, the present invention optimizes the extraction process, adopts compound enzymes to enzymatically hydrolyze the extract of konjac flying flour protein, and the content of konjac polypeptide in the finally obtained konjac polypeptide extract is as high as 85-97%, and konjac The molecular weight of the polypeptide is 350-3500Da. In addition, the present invention also provides the use of the konjac polypeptide extract in the preparation of the treatment of diabetes and diabetic complications, and the hypoglycemic pharmaceutical composition containing the konjac polypeptide extract. In a word, the konjac polypeptide extract of the present invention The compounds and their pharmaceutical compositions have good medical prospects.
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Description

technical field

[0001] The invention belongs to the field of medical biology, and specifically relates to a method for extracting konjac polypeptide extract from konjac powder, and the konjac polypeptide extract obtained by the method and the application of the konjac polypeptide extract. Background technique

[0002] Diabetes mellitus (DM) is a group of syndromes caused by environmental and genetic factors. Its basic pathological features are absolute or relative insufficiency of insulin secretion, or peripheral tissue insensitivity to insulin, mainly caused by glucose metabolism disorders, including A systemic disease characterized by disorders of fat and protein metabolism. Many evidence-based medical studies, such as the Clinical Trial of Diabetes Control and Complications (DCCT) and the UK Prospective Diabetes Study (UKPDS), have reached a consensus on the significance of intensified blood sugar control. Reaching the blood sugar target can not only prevent or delay chro...

Claims

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