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Enema particles for treating diabetic nephropathy and preparation method for enema particles

A technology for diabetic nephropathy and granules, applied in the fields of urinary system diseases, metabolic diseases, pharmaceutical formulations, etc., can solve problems such as insufficient consideration, and achieve the effect of facilitating the course of treatment, reducing the metabolic burden on the kidneys, and facilitating consolidation.

Inactive Publication Date: 2015-04-22
刘宝琴
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since the role of metabolic abnormalities caused by hyperglycemia in the pathological process of diabetic nephropathy is not fully considered, it is not helpful for delaying kidney damage

Method used

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  • Enema particles for treating diabetic nephropathy and preparation method for enema particles

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Example 1, the weight ratio of raw materials: 20 parts of hemp seed, 10 parts of mallow seed, 6 parts of Haixie, 10 parts of Hovenia trifoliata, 6 parts of fragrant fruit, 10 parts of shallot, 10 parts of dodder seed, golden buckwheat stem and leaf 10 parts, 10 parts of scorpion vine, 2 parts of gecko, 6 parts of bottle fern, 20 parts of Jiaoguya.

[0037] The preparation method of Example 1 is: mix hemp seed, mallow seed, sea squid, hovenia citrus, fragrant fruit, scallion, dodder, golden buckwheat stems and leaves, stellite vine, gecko, bottle fern, and burnt grain buds, add water and decoct , take the filtrate after 30 minutes, add water to the dregs and continue to decoct for 20 minutes, then take the filtrate, combine the two filtrates, and divide them into two parts for use in the morning and evening.

Embodiment 2

[0038]Example 2, the weight ratio of raw materials: 10 parts of hemp seed, 6 parts of mallow seed, 3 parts of sea sage, 6 parts of hovenia trifoliata, 3 parts of fragrant fruit, 6 parts of shallot, 6 parts of dodder seed, golden buckwheat stem and leaf 6 parts, 6 parts of terrazzo vine, 1 part of gecko, 3 parts of bottle fern, 10 parts of Jiaoguya.

Embodiment 3

[0039] Example 3, the weight ratio of raw materials: 20 parts of hemp seed, 10 parts of mallow seed, 6 parts of Haixie, 10 parts of Hovenia trifoliata, 6 parts of fragrant fruit, 10 parts of shallot, 10 parts of dodder seed, golden buckwheat stem and leaf 10 parts, 10 parts of scorpion vine, 2 parts of gecko, 6 parts of bottle fern, 20 parts of Jiaoguya.

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Abstract

The invention discloses enema particles for treating diabetic nephropathy and a preparation method for the enema particles. The problem that the diabetic nephropathy is difficult to treat is solved. The preparation method is characterized by comprising the following steps of (1) extracting essential oil from seeds of Chinese dodder, chingma abutilon seeds and angiospermae by steam distillation, and reserving the essential oil and dregs; (2) smashing gecko and coked rice sprout into fine powder, and reserving the fine powder; (3) performing blending and alcohol extraction on fructus cannabis, timonius arboreus, poncirus bark, allium victorialis, stem leaves of wild buckwheat rhizome, Chinese starjasmine stems, vandenboschia and dregs obtained from the step (1) twice, combining alcohol extracts, filtering the alcohol extracts, recycling ethyl alcohol, and performing vacuum concentration on the ethyl alcohol to obtain extractum; and (4) adding the fine powder obtained from the step (2) in the extractum obtained from the step (3), blending the fine powder and the extractum, drying the mixture at the temperature of 60 DEG C, smashing the mixture into fine powder, adding polysorbate-80 in the mixture to obtain particles, drying and granulating the particles, spraying the essential oil obtained from the step (1) in the particles, blending the particles and the essential oil, and separately packaging the particles to obtain the enema particles. A clinical experiment proves that the enema particles for treating the diabetic nephropathy have high curative effect and high safety, and are worthy of being clinically applied and popularized.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to an enema granule for treating diabetic nephropathy and a preparation method thereof. Background technique [0002] Diabetic nephropathy (diabetic nephropathy, DN) is one of the most important comorbidities of diabetic patients. Glomerulonephritis. Due to its complex metabolic disorders, once it develops into end-stage renal disease, it is often more difficult to treat than other kidney diseases. Therefore, timely prevention and treatment is of great significance for delaying diabetic nephropathy. The etiology and pathogenesis of diabetic nephropathy are unclear. Currently, it is believed that multiple factors are involved, and the disease is caused by a certain genetic background and some risk factors. The risk factors are: abnormal renal hemodynamics, abnormal metabolism caused by high blood sugar, high blood pressure, and abnormal metabolism of vasoactive substance...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61K9/16A61P13/12A61P3/10A61K35/583
Inventor 刘宝琴钟学文
Owner 刘宝琴
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