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A kind of traditional Chinese medicine composition for treating hepatitis B and its preparation method

A hepatitis B, composition technology, applied in the field of medicine, to achieve good therapeutic effect, significant curative effect, stable and controllable quality

Inactive Publication Date: 2015-09-09
GUANGZHOU SISHUNSHAN TRADITIONAL CHINESE MEDICINER & D
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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  • A kind of traditional Chinese medicine composition for treating hepatitis B and its preparation method
  • A kind of traditional Chinese medicine composition for treating hepatitis B and its preparation method
  • A kind of traditional Chinese medicine composition for treating hepatitis B and its preparation method

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Embodiment 1

[0018] Raw material ratio: 180g Daqingye, 270g comfrey, 54g red ginseng, 90g astragalus, 90g ground beetle, 90g dew hive, 18g centipede.

[0019] Preparation process: all raw materials are pulverized into fine powder, sterilized, tested, added with 50g of magnesium stearate, filled into capsules, and obtained.

Embodiment 2

[0021] The ratio of raw materials: 120g Daqingye, 80g comfrey, 60g red ginseng, 60g astragalus, 60g ground beetle, 60g dew hive, and 16g centipede.

[0022] Preparation process: all raw materials are sterilized by moist heat, pulverized into fine powder, mixed with 60 g of microcrystalline cellulose and 60 g of lactose, granulated with starch slurry, dried, added with 50 g of silicon dioxide, and pressed into tablets to obtain the product.

Embodiment 3

[0024] Raw material ratio: Daqingye 300g, comfrey 75g, red ginseng 150g, astragalus 150g, wood beetle 25g, dew hive 200g, centipede 40g.

[0025] Preparation process: Take Folium Folium Folium, Comfrey, Red Ginseng, and Astragalus plus 8 times 80% ethanol and heat and extract twice. The extract is concentrated under reduced pressure to form a thick paste for later use; , Centipede plus 10 times the amount of water decoction extraction 2 times, the extract was concentrated under reduced pressure to become a thick paste, and then extracted with alcohol to thick paste, vacuum dried to obtain 248g of dry paste. Crush the dry paste, add 80g of microcrystalline cellulose to granulate, mix with 25g of sodium carboxymethyl starch and 10g of silicon dioxide after granulation, and press into tablets to obtain the product.

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Abstract

The invention discloses a traditional Chinese medicine composition for treating hepatitis B. The composition is prepared from the following bulk drugs by weight: 5-30 parts of Nidus Vespae, 10-60 parts of folium isatidis, 15-40 parts of lithospermum, 5-30 parts of woodlouse, 5-30 parts of Astragalus membranaceus, 1-8 parts of centipede and 3-30 parts of red ginseng. The invention also discloses the preparation method of the above traditional Chinese medicine composition for treating hepatitis B. A first method comprises the steps of: grinding all bulk drugs, disinfecting, examining and preparing the preparation. A second method comprises the steps of: extracting lithospermum, folium isatidis, red ginseng and Astragalus membranaceus with ethanol; carrying out vacuum concentration on an extract and keeping the concentrated thick paste for standby; decocting medicinal slag and other bulk drugs with water for extraction; carrying out vacuum concentration on an extract; mixing an obtained thick paste with the thick paste obtained from alcohol extraction; drying to obtain a dry paste; evenly mixing the dry paste with accessories; and preparing the mixture into a pharmaceutically acceptable preparation, such as a tablet, a capsule, a pill, a powder and a particulate agent for clinic application. The traditional Chinese medicine composition provided by the invention has the advantages of novel formula, simple technology, stable and controllable quality, safety, effectiveness and substantial effect on the treatment of hepatitis B.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a traditional Chinese medicine composition for treating hepatitis B and a preparation method thereof. Background technique [0002] Hepatitis B infection is prevalent worldwide, and the epidemic intensity of HBV infection varies greatly in different regions. According to the report of the World Health Organization, about 2 billion people in the world have been infected with HBV, of which 350 million people are chronically infected, and there are about 1 million people every year. People died from HBV infection-induced liver failure, cirrhosis, and primary liver cancer (HCC). [0003] The results of the hepatitis B epidemic virus survey conducted in my country in 2006 showed that the HBsAg carrier rate of people aged 1 to 59 in my country was 7.18%, and the HBsAg carrier rate of children under 5 years old was only 0.96%. There are about 93 million people with chronic ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/481A61P31/20A61P1/16A61K35/64A61K35/648
Inventor 杨佩雄
Owner GUANGZHOU SISHUNSHAN TRADITIONAL CHINESE MEDICINER & D