Fukang expandable vaginal suppository, and preparation method and detection method thereof

A vaginal expansion suppository and detection method technology, applied in the field of vaginal suppositories, can solve the problems of outflow of active ingredients, unfavorable molding, and reduction of suppository bioavailability, and achieve the effect of avoiding secondary infection and preventing outflow
CN103520264AActive Publication Date: 2014-01-22哈尔滨田美药业股份有限公司
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
哈尔滨田美药业股份有限公司
Publication Date
2014-01-22

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Abstract

The invention relates to a Fukang expandable vaginal suppository, and a preparation method and a detection method thereof. The expandable suppository comprises active ingredients, a matrix and an expansion carrier. The active ingredients and the matrix form a drug-containing matrix, which is coated on the surface of the carrier. The active ingredients include walnut oil and further include motherwort and radix polygonati officinalis. The additional motherwort and radix polygonati officinalis can improve the curative effect of the Fukang expandable vaginal suppository on symptoms of leukorrhea with reddish discharge and bearing-down pain in lower abdomen; the starch sodium glycolate and walnut oil are prepared into a solid dispersion to improve the solubility of walnut oil and reduce volatilization of walnut oil; the stearic acid palmitic acid glycol ester improve the stability of the suppository; and the dextrin increases cohesiveness of the expandable suppository and is beneficial to forming the expandable suppository. The Fukang expandable vaginal suppository employs six unique technologies, and has beneficial effects of prevention of outflow liquid, high stability, lasting curative effect and prevention of secondary infection.
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Description

technical field

[0001] The invention belongs to the field of vaginal suppositories, in particular to a Fukang vaginal expansion suppository and a preparation method and detection method thereof. Background technique

[0002] Fukang suppository is a classic Chinese patent medicine, which is recorded in the seventeenth volume of "Ministry of Health's Drug Standards for Traditional Chinese Medicine Prescriptions". , has the effects of clearing heat and detoxifying, astringent and astringent, and is clinically used for red and white vaginal discharge, lower abdominal pain, and cervical erosion.

[0003] The curative effect of Fukang Suppository has been clinically confirmed for many years, but the walnut distilled oil in traditional Fukang Suppository is volatile and has low solubility, which leads to low content of active ingredients in the suppository and affects the bioavailability of the suppository; and the walnut distilled oil The suppository made of oil and glycerin gela...

Claims

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