Use of Dendrobium officinale Kimura et Migo fluid extract antidote in treatment on organophosphorus pesticide poisoning

Abstract

The invention relates to a use of a Dendrobium officinale Kimura et Migo fluid extract antidote in treatment on organophosphorus pesticide poisoning. Stems and branches of Dendrobium officinale Kimura et Migo growing for more than 2 years are used as main raw materials, and through a series of production processes, the Dendrobium officinale Kimura et Migo fluid extract antidote is obtained. The Dendrobium officinale Kimura et Migo fluid extract antidote contains a large amount of unique medicinal ingredients of precious Chinese herbal medicine Dendrobium officinale Kimura et Migo, and a spectroscopy identification result shows that the Dendrobium officinale Kimura et Migo fluid extract antidote contains 18 novel compounds. The novel compounds has medicinal effects of tonifying stomach and promoting secretion of saliva or body fluid, nourishing yin and clearing heat, improving immunity, resisting hypoxia, improving irritability and resisting poisoning. The medicinal effects of the Dendrobium officinale Kimura et Migo fluid extract antidote are used for treating organophosphorus pesticide poisoning, and the Dendrobium officinale Kimura et Migo fluid extract antidote has effects of improving a patient detoxification capacity, improving patient antioxidant defense system functions, effectively clearing free radicals and toxins in the human body, protecting patients from free radical damage, reducing complication, improving a curing rate, promoting patient recovery and assisting treatment. The Dendrobium officinale Kimura et Migo fluid extract antidote creates a precedent at home and abroad and fills a domestic blank.

Description

Technical field [0001] The invention relates to the medical treatment technology of dendrobium candidum, which belongs to the medical preparation and application of medicinal plants, and specifically relates to the application of dendrobium candidum liquid extract antidote in the treatment of organophosphorus pesticide poisoning. technical background [0002] Dendrobium officinale is a perennial epiphytic herb of Orchidaceae. It usually grows between 15°30′~25°12′ north latitude, on semi-shady rocks in mountains with an altitude of about 1400 meters. It likes warm and humid climate and half-yin and half-yang environment, and is not cold-resistant. Generally, they can withstand a low temperature of -5°C, and the species gradually decrease as they go northward. Dendrobium can be divided into dozens of species such as iron skin, yellow grass, nobile, horsewhip, etc. Dendrobium candidum is the best product of Dendrobium, and it is named for its iron-green skin. Dendrobium cand...

AI Technical Summary

Problems solved by technology

[0018] At present, it is believed that in patients with acute organophosphate poisoning, the hypothalamic release factor promotes the release of β-endorphin in the anterior pituitary gland, and the level of β-endorphin increases significantly, causing dysfunction of important organs, tissue hypoxia, and a large number of free radicals. The lipid peroxidation reaction is enhanced, the activity of the antioxidant enzyme superoxide dismutase (SOD) that scavenges free radicals is reduced, and the end product of oxidation, malondialdehyde (MDA), is increased, and the latter has cross-linking and polymerization effects on proteins and nucleic acids in patients , producing toxic effects on the normal metabolism of patient cells