Method for extracting herbaceous plants for external application by using small molecule cutting technology

A technology of herbal plants and cutting technology, which is applied in the field of small molecule cutting technology to extract herbal plants for external use, which can solve the problems of slow curative effect, limited development of Chinese herbal medicine, and complicated methods of use.

Inactive Publication Date: 2014-03-12
马建
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in the past, Chinese herbal medicines were mainly prepared into pills, powders, ointments, pills, soups, needles, medicines, teas and other medicaments for taking. The methods of use are complicated, the therapeutic effect is slow, and there are some potential risks.
In particular, the development of "three-effect" (high-efficiency, quick-acting, and long-acting) and "three-minor" (low toxicity, small side effects, and small dose) of pharmaceutical preparations has severely restricted the development of Chinese herbal medicines.

Method used

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  • Method for extracting herbaceous plants for external application by using small molecule cutting technology

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] a. Take 500 g of Bupleurum bupleuri for removing mildew and impurities, pulverize it and dissolve it in 5L of ethanol solution, place it in an ultrasonic grinding device and grind for 4 minutes, then filter the ground slurry to recover the filtrate;

[0027] b. Cool the recovered filtrate to below -12°C to make ice crystals form in the filtrate, then separate the generated ice crystals, use a centrifugal pump to separate the solute and ethanol in the ice crystals, and place the separated solute under a micro-laser Perform irradiation treatment; the wavelength of the micro-laser is 100-1000 nanometers, and the pulse width is 1-30 nanoseconds;

[0028] c. Dissolve the irradiated solute in 100ml ethanol to form a solution, stir the solution evenly and let it stand for 10 minutes, then cool the solution down to below -12°C to make ice crystals form in the filtrate, and then dissolve the solution The ice crystals are separated, and the solute and ethanol in the ice crystals ...

Embodiment 2

[0030] a. Take 500 g of Atractylodes atractylodis for removing mildew and impurities, pulverize it and dissolve it in 2L of acetone solution, place it in an ultrasonic grinding device and grind it for 10 minutes, then filter the ground slurry to recover the filtrate;

[0031] b. Cool the recovered filtrate to below -13°C to make ice crystals form in the filtrate, then separate the generated ice crystals, use a centrifugal pump to separate the solute and ethanol in the ice crystals, and place the separated solute under a micro-laser Perform irradiation treatment; the wavelength of the micro-laser is 100-1000 nanometers, and the pulse width is 1-30 nanoseconds;

[0032] c. Dissolve the irradiated solute in 150ml acetone to form a solution, stir the solution evenly and let it stand for 8 minutes, then cool the solution down to below -12°C to make ice crystals form in the filtrate, and then dissolve the solution The ice crystals are separated, and the solute and ethanol in the ice...

Embodiment 3

[0034] a. Get 500g of pinellia radix that removes mildew and impurities, dissolve it in 3L of carbon tetrachloride solution after being pulverized, place it in an ultrasonic grinding device and grind for 8min, then filter the ground slurry to reclaim the filtrate;

[0035] b. Cool the recovered filtrate to below -12°C to make ice crystals form in the filtrate, then separate the generated ice crystals, use a centrifugal pump to separate the solute and ethanol in the ice crystals, and place the separated solute under a micro-laser Perform irradiation treatment; the wavelength of the micro-laser is 100-1000 nanometers, and the pulse width is 1-30 nanoseconds;

[0036] c. Dissolve the irradiated solute in 100ml carbon tetrachloride to form a solution, stir the solution evenly and let it stand for 12 minutes, then cool the solution down to below -12°C so that ice crystals are formed in the filtrate, and then Then the generated ice crystals are separated, and the solute and ethanol ...

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Abstract

The invention discloses a method for extracting herbaceous plants for external application by using small molecule cutting technology. The method comprises the following steps: crushing herbaceous plants, adding a first solvent into the crushed herbaceous plants for grinding so as to obtain slurry, filtering the slurry and recovering a filtrate; separating the first solvent and a solute in the recovered filtrate and subjecting the separated solute to micro laser irradiation; and dissolving the irradiated solute in a second solvent to form a solution, successively stirring and standing the solution, separating the second solvent from a solute and recovering the solute which is an element-level active component. Through the micro laser irradiation and cutting of the solute after separation of the first solvent, the solute reaches the element level and maintains its activity and efficacy.

Description

technical field [0001] The invention relates to the field of medicine extraction, in particular to a method for extracting herbal plants for external use by using small molecule cutting technology. Background technique [0002] Since the 1990s, the research on pharmaceutical dosage forms and preparations has achieved remarkable development. Combining with multidisciplinary theories and advanced technologies, the research, development and production of pharmaceutical preparations have moved from an empirical model to a scientific and modernized path. . Modern pharmaceutical preparation technologies such as nanotechnology, liposome technology, microencapsulation technology, micronization technology, molecular inclusion technology, sustained and controlled release technology, needle-free injection drug delivery technology, laser pore-forming technology, osmotic pump controlled release technology, etc. As it matures, the research on pharmaceutical dosage forms and preparations ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/00A61K36/8888A61K36/284A61K36/258A61K36/233
Inventor 马建
Owner 马建
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