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Application of quercetin in preparing medicine for treating polycystic ovarian syndrome

A polycystic ovary and quercetin technology, which is applied in the application field of quercetin in the treatment of polycystic ovary syndrome drugs, can solve the problem of no research report on quercetin polycystic ovary syndrome insulin resistance, lack of radical cure. It can achieve good clinical application prospects, avoid surgical trauma, and reduce side effects.

Active Publication Date: 2014-04-09
SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is still a lack of radical treatment for PCOS. Western medicine mainly uses drugs and surgery, but the side effects of drugs are large, and there are complications such as pelvic and abdominal adhesions and ovarian function damage in the long-term after surgery, which limits its clinical application.
[0010] So far, there are no relevant research reports on the use of quercetin in the treatment of insulin resistance in polycystic ovary syndrome

Method used

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  • Application of quercetin in preparing medicine for treating polycystic ovarian syndrome
  • Application of quercetin in preparing medicine for treating polycystic ovarian syndrome
  • Application of quercetin in preparing medicine for treating polycystic ovarian syndrome

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Wister rats were selected to prepare polycystic ovary syndrome insulin resistance animal models, and drug intervention was performed on the successful model mice.

[0019] ELISA and other methods were used for detection, and statistical software SPSS17.0 was used for analysis to clarify the therapeutic effect and possible mechanism of quercetin on polycystic ovary syndrome insulin resistance animal models.

[0020] 1. Materials

[0021] 1.1 Experimental animals

[0022] Seventy-five 21-day-old SPF-grade female Wister rats were provided by Shanghai Slack Experimental Animal Co., Ltd., and were bred in the Animal Center of the Department of Marine Medicine, Second Military Medical University. 25 ℃ constant temperature (50% humidity) clean-grade breeding, without feeding vitamin products, 12h light and 12h dark cycle alternately.

[0023] 1.2 Main equipment

[0024] High-precision zoom optical microscope (BH-2 type of Japan PLYMPUS company), low temperature centrifuge (...

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Abstract

The invention relates to the technical field of traditional Chinese medicines, and provides application of quercetin in preparing a medicine for treating polycystic ovarian syndrome. A test is performed on a rat model with polycystic ovarian syndrome by adopting quercetin, and discovers that the quercetin has a remarkable treatment effect and can remarkably reverse insulin resistance. Quercetin does not have liver or kidney toxicity, is small in side effect, has a good clinical application prospect, does not have drug resistance, can avoid operative wounds, and obtains an excellent clinical effect in PCOS (polycystic ovary syndrome) treatment.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to an application of quercetin in medicine for treating polycystic ovary syndrome. Background technique [0002] Hawthorn (Hawthorn Fruit), also known as Shanlihong, is a plant in the family Rosaceae, and its fruit is used as medicine. Modern pharmacological research has found that Hawthorn contains more than 60 kinds of flavonoids, including Quercetin, Apigenin, Kaempferol, Luteolin and Bi-hydroflavonoids. , has the effects of lowering blood pressure, lowering blood fat, invigorating the stomach and stopping dysentery, enhancing myocardial contractility, increasing coronary flow, antiarrhythmia, and antibacterial. Traditional Chinese medicine believes that hawthorn is mild in nature, sour and sweet, and enters the spleen, stomach and liver meridians. [0003] Quercetin (Quercetin) is a flavonoid compound extracted from hawthorn fruit. dihydroxyphenyl)-3,5,7-...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/352A61P15/08
Inventor 俞超芹王针织翟东霞张丹英沈慰白玲玲俞瑾孙帅周丽虹黄丽红柴周芳
Owner SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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