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Application of Copper 2-Hydroxybenzoate as Feed High Copper Substitute

A technology of copper hydroxybenzoate and substitutes, applied in the field of livestock and poultry breeding, can solve problems such as affecting food safety, environmental pollution, excessive residues, etc., and achieve broad application prospects, reduce production costs, and reduce environmental pollution effects.

Active Publication Date: 2015-08-19
GUANGZHOU INSIGHER BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Through the experiment, the proportion of dermatitis nephropathy syndrome in weaned piglets using high copper is more than 5% higher than that of low copper, suggesting that high copper may be one of the inducements of porcine dermatitis nephropathy syndrome, and can lead to the decline of pig resistance
(2) High copper will affect food safety
Long-term application of high copper will leave excessive residues in animal tissues and organs, affecting food safety
(3) High copper can interfere with the absorption of other nutrients
(4) High copper also causes serious environmental pollution

Method used

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  • Application of Copper 2-Hydroxybenzoate as Feed High Copper Substitute

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Embodiment 1: the synthesis of 2-hydroxybenzoic acid copper

[0015] Weigh 80.0g of sodium 2-hydroxybenzoate and 20.0g of sodium hydroxide and dissolve them in 800ml of water, stir to dissolve and set the volume to 1000ml. Another 125.0g of copper sulfate pentahydrate was weighed, stirred and dissolved in water, and the volume was adjusted to 1000ml. Slowly pour the copper sulfate solution into the sodium 2-hydroxybenzoate / sodium hydroxide solution, stir while adding, and continue to stir and react for 30 minutes after adding the sample. After the reaction, the reaction solution was suction filtered and washed three times with water (2000 ml each time), and the filter cake was vacuum-dried under reduced pressure. A total of 102.3 g of product were obtained.

[0016] The product was taken for free water and crystal water analysis, and the free water content was 4.6%. The content of copper 2-hydroxybenzoate in the product is 97.59g, and the reaction yield is 97.59%.

...

Embodiment 2

[0020] Embodiment 2: the application effect of different doses of copper 2-hydroxybenzoate in feed for piglets

[0021] 70 52-day-old piglets from the nursery with similar body weight were divided into 7 groups, 10 pigs in each group, as shown in Table 1. Each group added different types or doses of copper compounds to the full-price compound feed for piglets without high copper content, and then fed and drank freely. The weight gain and feed remuneration of the test pigs in each test group were counted for 28 days. The results are shown in Table 2. It can be seen from Table 2 that 50-200ppm of copper 2-hydroxybenzoate (calculated as compounds, the same below) can significantly increase the daily gain of test pigs, improve the feed-to-meat ratio and reduce the diarrhea rate , and has a significant dose effect on the improvement of production performance. 150ppm copper 2-hydroxybenzoate can reach 800ppm (calculated by compound) copper sulfate to improve the production performa...

Embodiment 3

[0029] Embodiment 3: the application effect of copper 2-hydroxybenzoate in medium pig feed

[0030] 60 86-day-old, similar-weight Du Chang Sanyuan mixed lean meat pigs were divided into 6 groups as shown in Table 3, with 10 pigs in each group. Each group added different types or doses of copper compounds or other additives to the full-price compound feed for piglets without high copper content, and then had free access to food and water. The weight gain and feed remuneration of the test pigs in each test group were counted for 28 days. The result is shown in table 4, as can be seen from table 4, the production performance effect of the copper sulfate of 600ppm can be reached in the copper 2-hydroxybenzoate of 150ppm in middle pig growth stage, add 200ppm copper sulfate pentahydrate or 100ppm 2-hydroxybenzene separately Formic acid has a limited improvement on the growth performance of test pigs, and the test group (group 6) mixed with 2-hydroxybenzoic acid and copper in 2-hydr...

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Abstract

Provided is an application of copper 2-hydroxybenzoate as a substitute for high-dose copper for use in feed. Compared with copper sulfate, application of copper 2-hydroxybenzoate in an animal feed allows the amount of copper ions used to be reduced by nearly 75% while achieving an identical production performance, thus reducing toxic side effects of high-dose copper, reducing production costs, reducing environmental pollution, and providing a broad application prospect.

Description

Technical field: [0001] The invention belongs to the field of livestock and poultry breeding, and in particular relates to the application of copper 2-hydroxybenzoate as a high-copper substitute for feeding. Background technique: [0002] Copper is one of the essential trace elements for animals, and it participates in activities such as hematopoiesis, metabolism, growth and reproduction, and disease resistance of animals. The nutritional requirement of copper for animals is 5-8mg / kg, but since it was discovered in 1945 that high copper can significantly improve the growth performance of pigs, high copper has been widely used in the process of commercial pig breeding. At present, the use of 200-250ppm high copper (calculated as copper ions) in the young piglet stage can significantly improve the production performance of animals. [0003] In addition, high copper also has the effect of promoting growth in broiler chickens, and some broiler feeds also use high copper to prom...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23K1/16
CPCA23K1/16A23K1/1758A23K20/30
Inventor 彭险峰覃宗华
Owner GUANGZHOU INSIGHER BIOTECHNOLOGY CO LTD
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