Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Modified medical titanium metal material and preparation method thereof

A titanium metal modification technology, which is applied in the field of preparation of modified medical titanium metal materials, can solve problems such as weak bonding strength, easy peeling off and dissolution of the coating, achieve low production costs, realize large-scale industrial production, and have good anti-corrosion properties. The effect of bacteria ability

Inactive Publication Date: 2014-04-30
HENAN UNIV OF SCI & TECH
View PDF1 Cites 14 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to provide a modified medical titanium metal material to solve the problems of weak bonding strength between the existing medical titanium metal coating and the base material, and the coating is easy to fall off and dissolve

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Modified medical titanium metal material and preparation method thereof
  • Modified medical titanium metal material and preparation method thereof
  • Modified medical titanium metal material and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] The modified medical titanium metal material in this embodiment includes medical titanium metal. The surface of the medical titanium metal has a bioactive coating. Bonded silane coupling agent molecules are formed by in-situ polymerization and covalent grafting of polyaniline.

[0040] The medical titanium metal is pure titanium.

[0041] The preparation method of the modified medical titanium metal material of the present embodiment, such as figure 1 shown, including the following steps:

[0042] 1) Cleaning: Take a pure titanium sheet with a size of 10mm×10mm×1mm, and sequentially grind, polish, and ultrasonically clean it to obtain the cleaned titanium sheet for use;

[0043] 2) Surface hydroxylation: place the cleaned titanium sheet in piranha solution for oxidation treatment, the temperature of oxidation treatment is 50°C, take it out after 60 minutes of treatment, wash it with deionized water and dry it to get surface hydroxylated titanium piece;

[0044] 3) D...

Embodiment 2

[0047] The modified medical titanium metal material in this embodiment includes medical titanium metal. The surface of the medical titanium metal has a bioactive coating. Bonded silane coupling agent molecules are formed by in-situ polymerization and covalent grafting of polyaniline.

[0048] The medical titanium metal is pure titanium.

[0049] The preparation method of the modified medical titanium metal material of this embodiment comprises the following steps:

[0050] 1) Cleaning: Take a pure titanium sheet with a size of 10mm×10mm×1mm, and sequentially grind, polish, and ultrasonically clean it to obtain the cleaned titanium sheet for use;

[0051]2) Surface hydroxylation: place the cleaned titanium sheet in piranha solution for oxidation treatment, the temperature of oxidation treatment is 90°C, take it out after 2 minutes of treatment, wash it with deionized water and dry it to get surface hydroxylated titanium piece;

[0052] 3) Double bond on the surface: put the ...

Embodiment 3

[0055] The modified medical titanium metal material in this embodiment includes medical titanium metal. The surface of the medical titanium metal has a bioactive coating. Bonded silane coupling agent molecules are formed by in-situ polymerization and covalent grafting of polyaniline.

[0056] The medical titanium metal is pure titanium.

[0057] The preparation method of the modified medical titanium metal material of this embodiment comprises the following steps:

[0058] 1) Cleaning: Take a pure titanium sheet with a size of 10mm×10mm×1mm, and sequentially grind, polish, and ultrasonically clean it to obtain the cleaned titanium sheet for use;

[0059] 2) Surface hydroxylation: put the cleaned titanium sheet in piranha solution for oxidation treatment, the temperature of oxidation treatment is 75°C, take it out after 30 minutes of treatment, wash it with deionized water and dry it to get surface hydroxylated titanium piece;

[0060] 3) Double bond at the surface end: put ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a modified medical titanium metal material and a preparation method thereof. The modified medical titanium metal material comprises a medical titanium metal, wherein a bioactive coating is applied to the surface of the medical titanium metal, and is formed by performing surface hydroxylation on the medical titanium metal, introducing silane coupling agent molecules with terminal double bonds and covalently grafting polyaniline in an in-situ polymerization manner. The modified medical titanium metal material has excellent biocompatibility, bacteriostasis and stability because the bioactive coating is applied to the surface of the medical titanium metal, and has an excellent bacteriostatic capability to common strains, such as escherichia coli and staphylococcus aureus, with the bacteriostasis rate of over 90 percent; the bioactive coating is in chemical bonding with a matrix material, is high in bonding strength and can not easily fall off, so that the stability of an implant can be improved, and the service life of the implant can be prolonged.

Description

technical field [0001] The invention belongs to the technical field of medical titanium metal materials, specifically relates to a modified medical titanium metal material, and also relates to a preparation method of the modified medical titanium metal material. Background technique [0002] Due to their good biocompatibility, elastic modulus similar to that of bone tissue, and excellent corrosion resistance in biological environments, titanium metal and titanium alloys have been widely studied and clinically used in artificial bone substitute materials. However, titanium metal materials are biologically inert materials in nature and do not have biological activity themselves. As an implant and bone tissue, a strong chemical osseointegration cannot be formed, and there will be loosening after long-term use; In the process, the implant may introduce bacteria from the surrounding environment, which can cause postoperative infections such as osteomyelitis. In order to improve ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61L27/34A61L27/06A61L27/54
Inventor 彭淑鸽任萍祝迎春
Owner HENAN UNIV OF SCI & TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com