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Eucommia compound preparation for treating chronic constipation

A compound preparation and technology for chronic constipation, applied in the field of Eucommia compound preparations, to achieve a peaceful effect

Inactive Publication Date: 2014-06-18
HUBEI LAOLONGDONG DUZHONG DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the past, there were more foreign reports and fewer domestic reports

Method used

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  • Eucommia compound preparation for treating chronic constipation
  • Eucommia compound preparation for treating chronic constipation
  • Eucommia compound preparation for treating chronic constipation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Example 1 Basic recipe 1 preparation preparation: Eucommia ulmoides, pulverized, take 100 g, add 600-800 mL of water at room temperature, and extract twice at 80°C for 30-60 minutes each time, combine the filtrates from the two extractions for later use; 100g of senna, 100g of rhubarb, 100g of Polygonum multiflorum, 200g of cassia seeds, 100g of aloe vera, 100g of Polygonum cuspidatum, 100g of ginseng, add 9600ml of water at room temperature, soak for 2 hours, then simmer for 90 minutes, remove the residue to obtain a filtrate, and set aside. The filtrates obtained from the extraction of Eucommia ulmoides, senna, rhubarb, Polygonum multiflorum, cassia seeds, aloe vera, Polygonum cuspidatum, and ginseng were combined, concentrated under reduced pressure, spray-dried, added 50 g of dextrin and 50 g of starch, mixed uniformly, and prepared into granules.

Embodiment 2

[0026] Example 2 Basic recipe 2 Preparation: Eucommia ulmoides, pulverized, take 200 g, add 1200-1600 mL of water at room temperature, and extract twice at 80°C for 30-60 minutes each time, combine the filtrates extracted twice, and set aside; 100g of senna, 100g of rhubarb, 100g of Polygonum multiflorum, 100g of cassia seed, 100g of aloe vera, 100g of Polygonum cuspidatum, 100g of ginseng, add 8400ml of water at room temperature, soak for 2 hours, then simmer for 90 minutes, remove slag to obtain a filtrate for use. The filtrates obtained from the extraction of Eucommia ulmoides, senna, rhubarb, Polygonum multiflorum, cassia seeds, aloe vera, Polygonum cuspidatum, and ginseng were combined, concentrated under reduced pressure, spray-dried, added 50 g of dextrin and 50 g of starch, mixed uniformly, and prepared into granules.

Embodiment 3

[0027] Example 3 Preparation of basic prescription 3: Eucommia ulmoides, pulverized, take 900 g, add 5400-7200 mL of water at room temperature, and extract twice at 80°C for 30-60 minutes each time, combine the filtrates from the two extractions, and set aside; 100g, add 1200mL of water at room temperature, soak for 2 hours, then simmer for 90 minutes, remove the slag to obtain a filtrate, which is ready for use. The filtrates obtained by extracting Eucommia ulmoides and cassia seeds are combined, concentrated under reduced pressure, spray-dried, mixed evenly, and prepared into capsules.

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PUM

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Abstract

The invention relates to the field of drug formula, and specifically relates to a eucommia compound preparation for treating chronic constipation. The preparation method of the eucommia compound preparation comprises the following steps: taking eucommia, senna leaf, rheum officinale, fleece-flower root, cassia seed, aloe, gentrin knotweed, and polygonum bistorta as the raw materials; soaking the raw materials in water, decocting the raw materials, filtering to remove the dregs so as to obtain filtrate, condensing and drying the filtrate, adding property auxiliary materials, and finally making the mixture into various solid preparations such as capsules, tablets, and particles. The preparation is characterized by being composed of the following raw materials in percentage by weight: 20 to 90% of eucommia, 0 to 80% of senna leaf, 0 to 80% of rheum officinale, 0 to 80% of fleece-flower root, 0 to 80% of cassia seed, 0 to 80% of aloe, 0 to 80% of gentrin knotweed, 0 to 80% of polygonum bistorta, and the balance being auxiliary materials; wherein the preparation at least comprises one of senna leaf, rheum officinale, fleece-flower root, cassia seed, aloe, gentrin knotweed and polygonum bistorta, and the auxiliary material comprises at least one of starch, dextrin, microcrystalline cellulose, lactose, cane sugar, mannitol, silicon dioxide, and magnesium stearate. The eucommia compound preparation for treating chronic constipation has a good curative effect, can prevent melanosis coli if people use the preparation for a long term, and has a peace and safe effect.

Description

technical field [0001] The invention relates to a Chinese patent medicine preparation, in particular to a compound preparation of Eucommia ulmoides for treating chronic constipation. Background technique [0002] Constipation is one of the more common symptoms that makes people feel uncomfortable and even painful. The drugs currently used clinically for the treatment of constipation include volumetric laxatives, stimulant laxatives, lubricating laxatives, osmotic laxatives, prokinetics and 5-HF-4 receptor agonists. However, chronic constipation patients taking long-term laxatives containing anthraquinones, such as senna, rhubarb, Polygonum multiflorum, cassia seed, aloe vera, phenolphthalein, diacetin, fruit guide, castor oil, etc., lead to more and more reports of colon melanosis . In addition, volumetric laxatives magnesium sulfate, lubricating laxatives liquid paraffin, osmotic laxatives lactulose, and prokinetic drugs Cisabi Liu can also cause melanosis. In the past, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61P1/10
Inventor 刘冬成任治军刘芸芳
Owner HUBEI LAOLONGDONG DUZHONG DEV
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