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Traditional Chinese medicine thermosensible gel for treating hemorrhoids

A technology of temperature-sensitive gel and traditional Chinese medicine, which is applied in the direction of drug combination, pharmaceutical formula, aerosol delivery, etc., and can solve problems that have not been seen yet

Inactive Publication Date: 2014-12-10
安徽爱喆生物医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0015] At present, there has not yet been seen a product that mainly consists of Panax notoginseng, Moutan cortex, Phellodendron cortex, Sophora flavescens, Sophora japonica, Galla, and borneol, and Proxamer 407, Proxamer 188, benzalkonium bromide, and purified water as auxiliary materials. Report on external preparation of traditional Chinese medicine

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Take 400g of Panax notoginseng, 100g of cortex Moutan, 100g of Cortex Phellodendri, 100g of Sophora Sophora, 100g of Huaijiao, 50g of Galla Chinensis, and 150g of Borneol, grind Sanqi, Cortex of Moutan, Phellodendron Phellodendri, Sophora Sophorae, and Huaijiao into coarse powder, and extract by percolation In the tank, add 1 times the amount of 70% ethanol to soak for 24 hours, add 7 times the amount of 70% ethanol to percolate to obtain percolation liquid, recover ethanol under reduced pressure, and concentrate to obtain extract 1; put Galla gall in a multifunctional extraction tank, add 8 Double the amount of water and decoct twice, combine the filtrate, concentrate under reduced pressure to obtain extract 2; combine extract 1 and extract 2, mix evenly, and spray dry to obtain extract powder; put the borneol in a pulverizer, and pulverize into fine powder; The main medicine powder is obtained by mixing the extract powder and the fine powder of borneol in an equal ...

Embodiment 2

[0036]Take 200g Panax notoginseng, 150g Cortex Moutan, 150g Cortex Phellodendri, 150g Sophora Sophorae, 150g Sophorae Sinensis, 100g Galla Chinensis, and 100g Borneol, grind Panax notoginseng, Cortex Moutan, Phellodendron Phellodendron, Sophora Sophora Sophorae, Sophora Cortex Phellodendron into coarse powder, and extract by percolation In the tank, add 1 times the amount of 70% ethanol to soak for 24 hours, add 7 times the amount of 70% ethanol to percolate to obtain percolation liquid, recover ethanol under reduced pressure, and concentrate to obtain extract 1; put Galla gall in a multifunctional extraction tank, add 8 Double the amount of water and decoct twice, combine the filtrate, concentrate under reduced pressure to obtain extract 2; combine extract 1 and extract 2, mix evenly, and spray dry to obtain extract powder; put the borneol in a pulverizer, and pulverize into fine powder; The main medicine powder is obtained by mixing the extract powder and the fine powder of b...

Embodiment 3

[0040] Take 100g Panax notoginseng, 200g Cortex Moutan, 200g Cortex Phellodendri, 200g Sophora Sophora, 150g Sophorae Sinensis, 100g Galla Chinensis, and 500g borneol, crush Sanqi, Cortex Moutan, Phellodendron Cortex Phellodendron, Sophora Sophora Sophora, and Sophora japonica into coarse powder, and extract by percolation In the tank, add 1 times the amount of 70% ethanol to soak for 24 hours, add 7 times the amount of 70% ethanol to percolate to obtain percolation liquid, recover ethanol under reduced pressure, and concentrate to obtain extract 1; put Galla gall in a multifunctional extraction tank, add 8 Double the amount of water and decoct twice, combine the filtrate, concentrate under reduced pressure to obtain extract 2; combine extract 1 and extract 2, mix evenly, and spray dry to obtain extract powder; put the borneol in a pulverizer, and pulverize into fine powder; The main medicine powder is obtained by mixing the extract powder and the fine powder of borneol in ...

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PUM

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Abstract

The invention discloses a preparation method of a traditional Chinese medicine thermosensible gel for treating hemorrhoids. The preparation method comprises the following steps: weighing the raw materials in percentage by weight: 10-40 percent of panax notoginseng, 5-20 percent of cortex moutan, 5-20 percent of phellodendron, 5-20 percent of sophora flavescens ait, 5-15 percent of sophoricoside, 5-15 percent of galla chinensis and 5-15 percent of borneol; crushing the panax notoginseng, the cortex moutan, the phellodendron, the sophora flavescens ait and the sophoricoside into coarse powder, putting the coarse powder in a percolating extraction pot, adding 70 percent ethyl alcohol, soaking, percolating, and carrying out vacuum concentration to obtain a liquid extract 1; putting the galla chinensis in a multifunctional extraction pot, adding water, decocting twice, combining filtrates, and carrying out vacuum concentration to obtain a liquid extract 2; combining the liquid extract 1 and the liquid extract 2, and spray drying to obtain an extract powder; putting the borneol in a crusher, and crushing into fine powder; mixing the extract powder and the borneol fine powder according to an equivalent increasing method; and according to the weight ratio, adding 30-50 parts of poloxamer 407, 1-5 parts of poloxamer 188, 0.4-1 part of benzalkonium bromide and 180 parts of purified water after the per 100 parts of medicinal materials are extracted, so as to prepare the thermosensible gel. According to the preparation method, as water and the ethyl alcohol are used as extraction solvents only in the whole technological process, no wastewater and waste gas are generated in the production process, and the traditional Chinese medicine thermosensible gel is suitable for industrial production.

Description

[0001] technical field [0002] The invention relates to the field of traditional Chinese medicine preparations for external use, in particular to a traditional Chinese medicine temperature-sensitive gel for treating hemorrhoids. Background technique [0003] Hemorrhoids are a common and multiple anal disease. The traditional view generally defines hemorrhoids as soft veins formed by the expansion and varicose rectal veins under the mucous membrane of the end of the rectum and under the skin of the anal canal. Its main features are blood in the stool, prolapse, unbearable pain, and easy recurrence, which seriously affects people's normal work and life. The incidence of hemorrhoids is very high. According to statistics, 60% of the population suffers from hemorrhoids in varying degrees. There has been a saying in China since ancient times that "nine out of ten people have hemorrhoids". The age of onset of hemorrhoids can take place at any age from children to old age, but mos...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/756A61K9/06A61P9/14A61P1/00A61K35/64A61K31/045
Inventor 姜雪琪姜艳
Owner 安徽爱喆生物医药科技有限公司
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