Medicament for treating non-erosive gastro-oesophageal reflux disease and application of medicament

Abstract

The invention relates to a medicament for treating a non-erosive gastro-oesophageal reflux disease. The medicament is prepared from the following raw medicines in parts by weight: 10-14 parts of radix bupleuri, 10-14 parts of bitter orange, 2-4 parts of coptis chinensis, 2-4 parts of fructus evodiae, 10-14 parts of herba inulae, 13-17 parts of haematitum, 4-8 parts of stir-baked fructus gardeniae, 10-14 parts of rhizoma corydalis, 7-11 parts of fructus toosendan, 27-33 parts of Concha Arcaed, 2-4 parts of fresh ginger and 4-8 parts of liquorice. The invention also relates to an application of the medicament in preparation of a medicament for treating the non-erosive gastro-oesophageal reflux disease. Aiming at pathogenesis of the non-erosive gastro-oesophageal reflux disease of disorder qi and adverse rising of stomach qi, the medicament has efficacy of relieving liver, smoothing qi, harmonizing stomach and descending adverse qi. Proved by an experimental result, effective rate of the medicament is higher than that of the common medicament in market at present, recurrence rate after drug withdrawal is also low, and thus the medicament is worth popularizing.

Description

technical field [0001] The invention relates to a medicine for treating non-erosive gastroesophageal reflux disease and its application, in particular, it is a Chinese patent medicine prepared from raw materials with Chinese herbal medicine taste. Background technique [0002] Gastroesophageal reflux disease (GERD) is a common digestive system disease in clinical practice. It is caused by the dysfunction of the lower esophageal sphincter LES or the closing insufficiency of the pyloric sphincter, which causes the contents of the stomach and / or duodenum to be non-transient After long-term and repeated stimulation, it will cause hyperemia, edema, erosion and fibrosis of the esophageal mucosa. GERD includes non-erosive gastroesophageal reflux disease (NERD), erosive esophagitis (RE), and Barrett's esophagus. Those with GERD symptoms without endoscopic mucosal damage are called non-erosive gastroesophageal reflux disease, while those with histopathological changes in the esophag...

AI Technical Summary

Problems solved by technology

Its treatment effect on GRED is obvious, but the above-mentioned drugs need to increase or decrease the drugs on the basis of different pathological factors to achieve a better curative effect, which increases the difficulties in diagnosis and treatment, and the drug has no effect on the recurrence of NRED after treatment. situation is unclear

Therefore, there is an urgent need for a drug for the treatment of NRED that does not require syndrome differentiation and treatment, has significant curative effect and low recurrence rate, but there is no report on this type of drug at present