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Preparation method of probiotic chewing gum

A technology for probiotics and chewing gum, which can be applied to medical preparations without active ingredients, medical preparations containing active ingredients, and pharmaceutical formulas, and can solve the problems of low technical resolution, dependence, and poor repeatability.

Inactive Publication Date: 2015-03-04
NANCHANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, live bacteria technology is widely used in food, medicine and other fields as a common technology, but this technology has low resolution, poor repeatability, and depends on cultivation, so it is difficult to monitor some microorganisms with strict growth requirements

Method used

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Examples

Experimental program
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Effect test

Embodiment Construction

[0014] The preparation method of the present invention comprises the following steps:

[0015] 1、 Cultivation of probiotics: select probiotics after secondary activation and inoculate them into the culture medium for 24-48 hours;

[0016] The probiotics are: Bifidobacterium adolescentis, Bifidobacterium bifidum, Bifidobacterium animalis, Bifidobacterium breve, Bifidobacterium infantis, Bifidobacterium longum, Lactobacillus acidophilus, Lactobacillus casei, Lactobacillus crispatus, Lactobacillus delbrueckii, Lactobacillus bulgaricus, Lactobacillus fermentum, Lactobacillus gasseri, Lactobacillus helveticus, Lactobacillus delbrueckii, Lactobacillus paracasei, Lactobacillus plantarum, Lactobacillus reuteri, Lactobacillus rhamnosus or saliva Bacillus or combined use;

[0017] The probiotic inoculum is 5% of the total volume of the probiotic and the culture medium;

[0018] 2. Freeze-drying of probiotics: collect the cultured probiotics by centrifugation, and freeze-dry them over...

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PUM

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Abstract

The invention discloses a preparation method of probiotic chewing gum. The preparation method is characterized in that the residence time of probiotic bacteria in the oral cavity can be prolonged by adding the probiotic bacteria in chewing gum, and the effects of preventing and treating oral diseases such as pulpitis, periapical periodontitis, gingivitis, periodontitis, acute necrotizing ulcerative periodontitis, stomatitis and the like can be achieved by virtue of the antagonistic action of oral probiotic bacteria on oral pathogenic bacteria. The preparation method disclosed by the invention has the advantages that the probiotic bacteria are long in action time in the oral cavity and good in curative effect, are safe and green, and are suitable for various oral patients and normal people.

Description

technical field [0001] The invention relates to a preparation method of probiotic chewing gum which is specially used for preventing and treating oral flora disorder type diseases. Background technique [0002] Microorganisms can lead to oral diseases, such as pulpitis, periodontitis, gingivitis, periodontitis, acute necrotizing ulcerative periodontitis, stomatitis, etc. In the past, considering that Streptococcus mutans was often isolated from the lesion of dental caries patients, trying to use antibiotics to remove it has achieved the purpose of preventing caries, but the results have little effect. The reason is that Streptococcus mutans is one of the members of the normal flora in the oral cavity. To completely remove it, the operation is difficult, and the two will seriously damage the original micro-ecological balance of the oral cavity, resulting in flora imbalance. . Therefore, dental caries and periodontal disease are theoretically caused by the imbalance of norma...

Claims

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Application Information

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IPC IPC(8): A61K35/747A61K35/745A61K9/68A61P1/02
CPCA61K35/747A61K9/0058A61K35/745A61K47/36
Inventor 陈廷涛邓侃辛洪波
Owner NANCHANG UNIV
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