Alkaloid microcapsule and preparation method thereof

Abstract

The invention relates to an alkaloid microcapsule and a preparation method thereof. The alkaloid microcapsule comprises a capsule core and a capsule wall, wherein the capsule core comprises one or more alkaloids extracted from aconite, aconitum pendulum, mandala, black false hellebore, radix sophorae flavescentis and semen strychni; the capsule wall comprises polyurea which is prepared from polyamine and polyisocyanate. The bitter taste of the alkaloid is covered by microcapsule coating, and the stability of the alkaloid is certainly improved. The alkaloid inside the microcapsule can be slowly released for a long time by the effect of the external environment, so the medicinal effect time is prolonged; the acute toxicity of the alkaloid is certainly alleviated and the alkaloid is chronic in toxicity; on one hand, the vigilance of insects can be reduced; on the other hand, harms to beneficial organisms and humans can be reduced, so the alkaloid microcapsule belongs to an environment-friendly pesticide.

Description

technical field [0001] The invention relates to the fields of pesticides and medicines, in particular to an alkaloid microcapsule and a preparation method thereof. Background technique [0002] Alkaloids are a class of basic compounds containing nitrogen atoms, which mainly exist in higher plants in nature. There are many kinds of known alkaloids with complex structures. Most alkaloids are colorless solids with a bitter taste. The water solubility of alkaloids is generally poor, but they are easily soluble in organic solvents such as ether, chloroform, methylene chloride, etc. The salts formed by the reaction of alkaloids and acids are usually easily soluble in water, so the extraction of alkaloids is usually carried out using acid-base Adjust the extraction method. [0003] Most alkaloids have pharmacological effects or toxicity to animals and can therefore be used as drugs, such as caffeine and nicotine as stimulants, morphine and codeine as analgesics, quinine as antim...

AI Technical Summary

Problems solved by technology

Although compared with traditional chemical insecticides, alkaloid insecticides have a unique mode of action, and insects are less likely to develop resistance, but there are many disadvantages in the direct use of alkaloid insecticides, such as the poor palatability of alkaloids, and the attraction of insecticides. The effect of pests is not ideal; alkaloids are easy to degrade in the natural environment, and the drug has a short period of validity; some alkaloids have strong acute toxicity, which is more likely to cause the vigilance of pests and their kind, thereby causing food refusal; Faster catabolism in the body, resulting in shorter duration of action

On the other hand, many alkaloids are highly toxic to humans, thus causing harm to the living environment of humans

Due to the above reasons, the application of alkaloids in the field of pesticides has been greatly restricted

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