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Pharmaceutical composition for preventing and treating influenza and preparation method of pharmaceutical composition

A technology for influenza and a composition is applied in the field of pharmaceutical compositions for preventing and treating influenza and the field of preparation thereof, which can solve the problems of adverse reactions of the respiratory system, side effects of the nervous system, limited application scope, etc. The effect of low and high clinical application value

Inactive Publication Date: 2015-04-01
QINGDAO CENT HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, when a patient goes to the hospital, even if the symptoms are very similar to "flu", it is difficult for the doctor to make a diagnosis of "flu". They can only make a diagnosis of "flu-like illness". According to the definition, as long as the body temperature (armpit temperature) is greater than 38° C, accompanied by at least one respiratory symptom (such as: sore throat, cough, etc.), it can be diagnosed as "influenza-like case", but the diagnosis of "influenza" requires "etiological diagnosis", including the cultivation of influenza virus from respiratory specimens Or detect the influenza virus antigen, most general hospitals do not have the ability of pathogenic detection at present
[0004] For influenza, the current common treatment methods include symptomatic treatment, that is, antipyretic and analgesic treatment for fever, headache and other symptoms, and antiviral treatment, such as ion channel M2 protein inhibitors, neuraminidase Inhibitors and other drugs, but symptomatic treatment cannot cure influenza disease, and the effect is slow. Antiviral drugs are likely to cause nervous system side effects in patients with renal dysfunction, and are very likely to cause adverse reactions in other systems such as the respiratory system. Application extremely limited range

Method used

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  • Pharmaceutical composition for preventing and treating influenza and preparation method of pharmaceutical composition

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Embodiment 1: decoction

[0018] Prescription: 50 grams Nepeta, 50 grams Fangfeng, 50 grams Chinese fennel, 50 grams perilla, 50 grams notopterygium, 50 grams Bupleurum, 35 grams purslane, 35 grams ten merits, 35 grams dandelion, 35 grams Coptis chinensis, Cortex Phellodendri 35 grams, 35 grams of trigeminus, 35 grams of marigold, 35 grams of syringa, 35 grams of root, 45 grams of asparagus, 45 grams of dendrobium, 45 grams of Polygonatum odoratum, 45 grams of Polygonatum, 45 grams of Morinda officinalis, 45 grams of Cistanche gram.

[0019] Preparation method: Take the above raw materials and medicines, mix them into a casserole, add water to soak the noodles for 30 minutes, boil on high heat, then change to a slow fire and cook for 30 minutes, filter out the medicine solution, add water and cook for 20 minutes, filter out the medicine solution, twice The filtrates were combined.

[0020] Dosage: One dose per day, twice in the morning and evening after meals.

Embodiment 2

[0021] Embodiment 2: tablet

[0022] Prescription: 15 grams Nepeta, 15 grams Fangfeng, 15 grams fennel, 15 grams perilla, 15 grams notopterygium, 15 grams Bupleurum, 25 grams purslane, 25 grams ten merits, 25 grams dandelion, 25 grams Coptis chinensis, Cortex Phellodendri 25 grams, 25 grams of trigeminal bitter, 25 grams of marigold, 25 grams of sheep's foot, 25 grams of root, 40 grams of asparagus, 40 grams of dendrobium, 40 grams of Polygonatum odoratum, 40 grams of sealwort, 40 grams of Morinda officinalis, 40 grams of cistanche gram.

[0023] Preparation method: Mix the above-mentioned raw materials, add 8 times the amount of raw materials in water, decoct for 30 minutes for the first time, filter to obtain filtrate 1, add 6 times the amount of raw materials to water and decoct for 30 minutes, filter to obtain filtrate 2, and combine the two filtrates , concentrated to a concentrated solution with a relative density of 1.1-1.2 at room temperature, adding an ethanol solu...

Embodiment 3

[0025] Embodiment 3: soft capsule

[0026] Prescription: 90 grams Nepeta, 90 grams Fangfeng, 90 grams Chinese fennel, 90 grams perilla, 90 grams notopterygium, 90 grams Bupleurum, 50 grams purslane, 50 grams ten merits, 50 grams dandelion, 50 grams Coptis chinensis, Cortex Phellodendri 50 grams, 50 grams of trigeminal bitter, 50 grams of marigold, 50 grams of sheep's foot, 50 grams of root, 50 grams of asparagus, 50 grams of dendrobium, 50 grams of Polygonatum odoratum, 50 grams of sealwort, 50 grams of Morinda officinalis, 50 grams of cistanche gram.

[0027] Preparation method: Mix the above-mentioned raw materials, add 8 times the amount of raw materials in water, decoct for 30 minutes for the first time, filter to obtain filtrate 1, add 6 times the amount of raw materials to water and decoct for 30 minutes, filter to obtain filtrate 2, and combine the two filtrates , concentrated to a concentrated solution with a relative density of 1.1-1.2 at room temperature, adding a...

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PUM

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Abstract

The invention relates to a pharmaceutical composition for treating influenza and a preparation method and pharmaceutical application of the pharmaceutical composition. The pharmaceutical composition comprises the following medicines in parts by weight: 5-100 parts of fineleaf schizonepeta herb, 5-100 parts of divaricate saposhnikovia root, 5-100 parts of Chinese mosla herb, 5-100 parts of perilla, 5-100 parts of incised notopterygium rhizome, 5-100 parts of Chinese thorowax root, 15-70 parts of herba portulacae, 15-70 parts of leatherleaf mahonia leaf, 15-70 parts of Mongolian dandelion herb, 15-70 parts of golden thread, 15-70 parts of amur corktree bark, 15-70 parts of thin evodia twigs and leaves, 15-70 parts of marigold, 15-70 parts of sowthistle tasselflower herb, 15-70 parts of roughhaired holly root, 30-60 parts of cochinchinese asparagus root, 30-60 parts of dendrobium, 30-60 parts of fragrant solomonseal rhizome, 30-60 parts of manyflower solomonseal rhizome, 30-60 parts of medicinal Indianmulberry root and 30-60 parts of desertliving cistanche. The pharmaceutical composition provided by the invention has the beneficial effects that the traditional Chinese medicines are taken as raw materials, the advantages of low toxic and side effects of the traditional Chinese medicines are realized, the effects of preventing and treating the influenza are realized, and the pharmaceutical composition is safe, effective, low in cost and easy to realize extensive popularization, and has relatively high clinical application values.

Description

technical field [0001] The invention relates to a pharmaceutical composition, a preparation method and pharmaceutical application thereof, in particular to a pharmaceutical composition for treating influenza, a preparation method and pharmaceutical application thereof. Background technique [0002] Influenza (abbreviated as influenza) is an acute respiratory infection caused by influenza virus, and it is also a highly contagious and fast-spreading disease. It is mainly transmitted through droplets in the air, contact between people or contact with contaminated items. Typical clinical symptoms are: sudden onset of high fever, general pain, significant fatigue and mild respiratory symptoms. During the high-incidence period, the complications and death caused by it are very serious. The disease is caused by influenza virus and can be divided into three types: A (A), B (B) and C (C). Type A virus often undergoes antigenic variation , highly contagious, spreads rapidly, and is e...

Claims

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Application Information

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IPC IPC(8): A61K36/8984A61P31/16
CPCA61K9/0095A61K9/205A61K9/4866A61K36/185A61K36/233A61K36/237A61K36/238A61K36/28A61K36/288A61K36/29A61K36/53A61K36/535A61K36/538A61K36/64A61K36/718A61K36/746A61K36/754A61K36/756A61K36/8965A61K36/8969A61K36/8984A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 周学锋马宝花刘雪丽杨海
Owner QINGDAO CENT HOSPITAL
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