Pharmaceutical composition with anti-aging effect
A composition and anti-aging technology, applied in the direction of drug combination, application, anti-toxic agent, etc., can solve the problems of unpublished related effects and undisclosed extracts, etc., and achieve the effect of prolonging life, significant effect, and prolonging life
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Embodiment 1
[0034] The acquisition of monomeric compounds
[0035] 5 kg of traditional Chinese medicine Radix Astragali was pulverized, extracted three times with 95% ethanol under reflux, combined the three extracts, concentrated under reduced pressure, and dried in vacuum to obtain 182 g of extract. Suspend the extract with about 10 times the amount of water, and extract with chloroform, ethyl acetate, and n-butanol in sequence. After recovering the solvent, extracts of various fractions were obtained. The chloroform extraction site was subjected to repeated silica gel chromatography, eluted with different proportions of petroleum ether-acetone gradient, and crystallized with acetone to obtain the compound 7,2'-dihydroxy-3',4'-dimethoxyisoflavan, Formononetin, Calycosin. The ethyl acetate extraction part was subjected to repeated normal phase silica gel chromatography with chloroform-methanol gradient elution and reverse phase silica gel chromatography with methanol-water gradient elu...
Embodiment 2
[0046] The anti-aging pharmaceutical composition is formulated from the following monomer compounds in parts by weight (unit: mg)
[0047]
[0048] The pharmaceutical composition of this example significantly prolongs the average lifespan of adult nematodes, and exhibits a dose-dependent effect.
Embodiment 3
[0050] The anti-aging pharmaceutical composition is formulated from the following monomer compounds in parts by weight (unit: mg)
[0051]
[0052] The pharmaceutical composition of this example significantly prolongs the average lifespan of adult nematodes, and exhibits a dose-dependent effect.
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