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Composite zinc silver antibacterial agent contained chitosan fiber dressing and preparation method thereof

A technology of chitosan fiber and antibacterial agent, which is applied in the field of chitosan fiber dressing containing composite silver-zinc antibacterial agent and its preparation, can solve the problems of skin inflammation without antibacterial drugs, antibiotic resistance, and difficulty in controlling the disease. Achieving the effects of fast sterilization speed and duration, low toxicity, and maintaining the concentration of bactericidal factors

Inactive Publication Date: 2015-09-02
SHENZHEN TSINGHUA YUANXING NANO MATERIAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] With the development of industrialization, various pollutants are discharged, the environment changes rapidly, and various skin inflammations occur frequently. Many skin inflammations have no specific antibacterial drugs; the incidence of burns, scalds and decubitus infections increases, and more antibiotics are used. It is easy to develop drug resistance and it is difficult to control the disease

Method used

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  • Composite zinc silver antibacterial agent contained chitosan fiber dressing and preparation method thereof
  • Composite zinc silver antibacterial agent contained chitosan fiber dressing and preparation method thereof
  • Composite zinc silver antibacterial agent contained chitosan fiber dressing and preparation method thereof

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preparation example Construction

[0032] The preparation method of the composite silver-zinc antibacterial agent is as follows: (1) take the silver compound that the mass fraction is 10%-20%, the zinc compound that the mass fraction is 20%-40%, the balance is an inert carrier, and the three are mixed Evenly, put it in a porcelain dish; (2) put it into a high-temperature furnace and burn it at 1000 ° C for 1-3 hours; (3) pass through a 200-mesh sieve after cooling, take the under-sieve, and mix evenly to obtain a composite silver-zinc antibacterial agent.

[0033] Preferably, the surface of the chitosan fiber dressing containing the composite silver-zinc antibacterial agent is also covered with a self-adhesive matrix layer or a release paper layer or a hydrocolloid layer; wherein the self-adhesive matrix layer is selected from spraying medical pressure One of the polyurethane composite films and non-woven fabrics of sensitive glue; the release paper layer is selected from glassine paper or CCK paper or a kind o...

Embodiment 1-5

[0036] The proportioning of specific embodiments of the present invention is shown in Table 1.

[0037] The following raw materials are respectively taken in parts by weight: 90-100 parts of chitosan fiber dressing, 2-4 parts of composite silver-zinc antibacterial agent, 90-95 parts of dispersant, and 1-7 parts of suspending agent.

[0038] Table 1 The proportioning table of Embodiment 1-5

[0039]

[0040] Above-mentioned raw material is prepared the chitosan fiber dressing containing composite silver-zinc antibacterial agent according to the following steps, and it comprises the following steps successively:

[0041] (1) Preparation of composite silver-zinc antibacterial agent: take mass fraction of silver compound of 10%-20%, zinc compound of 20%-40% of mass fraction, the balance is an inert carrier, mix the three evenly, place Put it in a porcelain dish; then put it into a high-temperature furnace and burn it at 1000°C for 3 hours; pass through a 200-mesh sieve after c...

Embodiment 6-15

[0058] Studies have found that when the ratio of nano-silver and nano-zinc is within a certain range, their bactericidal effect will increase synergistically. Below, under the ratio of raw materials in Example 2, observe the impact of chitosan fiber dressings containing different ratios of nano-silver and nano-zinc on the antibacterial and bactericidal effects of Staphylococcus aureus, Pseudomonas aeruginosa, and Candida albicans , the results are shown in Table 3.

[0059] Table 3: Effects of chitosan fiber dressings containing different ratios of nano-silver and nano-zinc on the bactericidal rate of Staphylococcus aureus, Pseudomonas aeruginosa, and Candida albicans

[0060]

[0061]

[0062] As can be seen from Table 3, the chitosan fiber dressing containing composite silver-zinc antibacterial agent of the present invention has very strong antibacterial and bactericidal action to Staphylococcus aureus, Pseudomonas aeruginosa, Candida albicans, and the bactericidal eff...

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Abstract

The invention discloses a composite zinc silver antibacterial agent contained chitosan fiber dressing which comprises a dressing body and antibacterial active components attached to the dressing body. The dressing body is a wound dressing made of chitosan fibers, the antibacterial active components are made of raw materials comprising, by weight, 2-4 parts of composite zinc silver antibacterial agents, 90-95 parts of dispersing agents and 1-7 parts of suspending agents. The composite zinc silver antibacterial agent contained chitosan fiber dressing can be widely applied to treatment of infectious wounds, surgical incisions, surgical traumas, body surface ulcers and various burning and scalding wounds, anti-bacteria, bleeding stopping, anti-inflammation and deodorization functions are achieved, and antibacterial and growth promoting effect especially for the infected wounds with more percolate is more remarkable.

Description

technical field [0001] The invention relates to the field of medical dressings, more specifically, relates to a chitosan fiber dressing containing a composite silver-zinc antibacterial agent that has excellent antibacterial properties, can promote wound healing, tissue repair regeneration and absorb wound exudate and its preparation method. Background technique [0002] With the development of industrialization, various pollutants are discharged, the environment changes rapidly, and various skin inflammations occur frequently. Many skin inflammations have no specific antibacterial drugs; the incidence of burns, scalds and decubitus infections increases, and more antibiotics are used. It is easy to develop drug resistance and it is difficult to control the disease. The skin is the first immune barrier of human beings, which can prevent the loss of water and electrolytes in the body, and protect the body from the direct harm of radiation, chemicals, bacteria and viruses in th...

Claims

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Application Information

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IPC IPC(8): A61L15/28A61L15/44A61L15/42A61L15/18
Inventor 杨新庆高培军刘龙清黄建林
Owner SHENZHEN TSINGHUA YUANXING NANO MATERIAL CO LTD
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