Traditional Chinese medicine smeared film for post-operation wound healing

A technology of wound healing and film-coating agent, which is applied in the field of traditional Chinese medicine film-coating agent for wound healing after anorectal surgery and its preparation, which can solve the problems of severe, local pollution, and slow healing

Inactive Publication Date: 2015-12-23
陈红
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Anal diseases are a common and frequently-occurring disease, with a prevalence rate of about 50-70%. For example, common clinical anal fistula, hemorrhoids, anal fissure and other diseases often require surgical treatment. The physiological function of the anorectum is relatively serious, and the local pollution is relatively serious. The postoperative wound is usually treated openly. The wound inflammation caused by intestinal bacteria leads to slow healing, which causes great pain to the majority of patients. Therefore, wound healing has become the focus of research in the anorectal field.

Method used

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  • Traditional Chinese medicine smeared film for post-operation wound healing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0069] Formula: by weight percentage, traditional Chinese medicine clear ointment 10%, polyvinyl butyral 1.5%, dibutyl phthalate 0.4%, chitosan 1.1%, glycerol 6%, laurocaprolactone 1.0% , 30% ethanol, and the balance is water;

[0070] Prescription of clear ointment: 28 parts of three needles, 18 parts of mountain pepper leaves, 20 parts of red nan root, 12 parts of Galla chinensis, 20 parts of bark vine, 10 parts of nepeta, 15 parts of Panax notoginseng, 10 parts of mahogany.

[0071] The preparation method of the film coating agent: take the vine, Panax notoginseng and Hongmuxiang, percolate with water, collect the percolation liquid, pass the percolation liquid through the macroporous adsorption resin, and first elute with water to remove impurities soluble in polar solvents, The water eluate was discarded; then eluted with 70% ethanol, and the ethanol eluate of Hydrangea was collected;

[0072]Grind the three needles, mountain pepper leaves, red nan root, gallnut, and Nep...

Embodiment 2

[0075] Formula: by weight percentage, traditional Chinese medicine clear paste 15%, polyvinyl butyral 1.9%, dibutyl phthalate 0.3%, chitosan 1.3%, glycerol 7%, laurocaprazine 1.0% , ethanol 34%, and the balance is water;

[0076] Prescription of clear ointment: 28 parts of three needles, 18 parts of mountain pepper leaves, 20 parts of red nan root, 12 parts of Galla chinensis, 20 parts of bark vine, 10 parts of nepeta, 15 parts of Panax notoginseng, 10 parts of mahogany.

[0077] The preparation method of the film coating agent: take the vine, Panax notoginseng and Hongmuxiang, percolate with water, collect the percolation liquid, pass the percolation liquid through the macroporous adsorption resin, and first elute with water to remove impurities soluble in polar solvents, Discard the water eluate and use it; elute with 70% ethanol to collect the ethanol eluate of C. chinensis, Panax notoginseng and Hongmuxiang;

[0078] Grind the three needles, mountain pepper leaves, red na...

Embodiment 3

[0081] Formula: by weight percentage, traditional Chinese medicine clear paste 20%, polyvinyl butyral 2.4%, dibutyl phthalate 0.5%, chitosan 1.6%, glycerol 7.5%, laurocaprolactone 1.2% , 35% ethanol, and the balance is water;

[0082] Prescription of clear ointment: 28 parts of three needles, 18 parts of mountain pepper leaves, 20 parts of red nan root, 12 parts of Galla chinensis, 20 parts of bark vine, 10 parts of nepeta, 15 parts of Panax notoginseng, 10 parts of mahogany.

[0083] The preparation method of the film coating agent: take the vine, Panax notoginseng and Hongmuxiang, percolate with water, collect the percolation liquid, pass the percolation liquid through the macroporous adsorption resin, and first elute with water to remove impurities soluble in polar solvents, The water eluate was discarded and not used; and then eluted with 70% ethanol to collect the ethanol eluate of Cinnamomum chinensis, Panax notoginseng and Hongmuxiang;

[0084] Grind three needles, mou...

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Abstract

The invention belongs to the field of traditional Chinese medicines, and relates to a traditional Chinese medicine smeared film for post-operation wound healing and a preparation method thereof. The traditional Chinese medicine smeared film is prepared from 1 to 30 percent of traditional Chinese medicine clear paste, 1 to 5 percent of polyvinyl butyral, 0.3 to 0.8 percent of dibutyl phthalate, 0.5 to 2.5 percent of chitosan, 3 to 10 percent of glycerin, 0.5 to 1.5 percent of laurocapram, 15 to 40 percent of ethyl alcohol and the balance of water, wherein the traditional Chinese medicine clear paste is prepared from barberry root, lindera glauca leaf, syzygium buxifolium, Chinese gall, creeping mallotus root or leaf, fineleaf schizonepeta herb, pseudo-ginseng leaf and kadsura longipedunculata, has the effects of clearing heat, promoting diuresis, activating blood, promoting tissue regeneration, and relieving swelling and pain, can promote wound healing, and also has an anti-bacterial effect and an analgesic effect. The smeared film can be adhered to a wounded part, bacteria are isolated, a wounded surface can be cleaned favorably by self-dissolution, generated tissue fluid is adsorbed, the smeared film cannot be adhered to the skin and is easy to tear off, the secondary injury is avoided, and the smeared film is high in air permeability, convenient to use and greater in clinical popularization value.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine coating agent for wound healing after anorectal surgery and a preparation method thereof. Background technique [0002] Anal diseases are a common and frequently-occurring disease, with a prevalence rate of about 50-70%. For example, common clinical anal fistula, hemorrhoids, anal fissure and other diseases often require surgical treatment. The physiological function of the anorectum is relatively serious, the local pollution is relatively serious, and the postoperative wound is usually treated openly. The wound inflammation caused by intestinal bacteria leads to slow healing, causing great pain to the majority of patients. Therefore, wound healing has become the focus of research in the anorectal field. [0003] It is generally believed that the wound healing process can be roughly divided into three distinct but overlapping...

Claims

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Application Information

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IPC IPC(8): A61K36/61A61K47/36A61K47/32A61K9/70A61P1/00A61P17/02A61K35/64
Inventor 李海云
Owner 陈红
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