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Electrostatic spinning device for preparing axial orderly arranged tubes by means of magnetic field inducement

An electrospinning, ordered arrangement technology, applied in textiles and papermaking, filament/thread forming, fiber processing, etc., can solve the problem of less research on three-dimensional ordered tubular stents

Inactive Publication Date: 2015-12-30
BEIHANG UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] However, there are still few studies on the preparation of three-dimensional ordered tubular scaffolds by magnetic spinning

Method used

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  • Electrostatic spinning device for preparing axial orderly arranged tubes by means of magnetic field inducement

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Experimental program
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Embodiment 1

[0020] Embodiment 1, adopt as figure 1 The device shown performs electrospinning. Poly(lactic-co-glycolic acid) (PLGA) (Mv=5×10 4 KDa) was dissolved in N,N-dimethylformamide (DMF) / dichloromethane, the volume ratio of DMF and dichloromethane was 1:1, and the mass volume ratio of PLGA was 36wt.%. in the reservoir. The high-voltage DC power supply voltage is 12kV, the positive pole is connected to the needle of the stainless steel syringe, and the rotation speed of the roller is controlled by the motor and grounded through the wire. The micro-injection pump fixed with the liquid reservoir is placed vertically, and the distance from the stainless steel injection needle tip to the drum is 15 cm. The outer diameter of the ring magnet is 7cm, the inner diameter is 3cm (consistent with the outer diameter of the drum), and the distance between the two magnets is 5cm. In this example, the diameter of the drum is 3cm, and the rotating speed is 2000r / min. The inner diameter of the in...

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Abstract

The invention provides an electrostatic spinning device for preparing axial orderly arranged tubes by means of magnetic field inducement. The device can be used for preparing three-dimensional orderly arranged tubular tissue engineering scaffold materials. The device comprises a micro-injection pump, a reservoir, a conductive capillary tube, a direct-current high-voltage power supply, a receiving device and annular ferrite magnets, wherein the reservoir is a glass injector and fixed to the micro-injection pump, the micro-injection pump can accurately control spinning solution extrusion rate, the conductive capillary tube is a stainless steel injection needle with the top end ground flat, the receiving device is a roller connected with a motor, the positive pole of the direct-current high-voltage power supply is connected with the stainless steel injection needle, and the roller serving as the receiving device is grounded through a wire so that a high-voltage electric field can be generated between the head of the stainless steel injection needle and the receiving device; the roller is sleeved with a pair of annular ferrite magnets which rotate together with the roller, and the distance between the two magnets is 4-10 cm so that the receiving device can be in a stable magnetic field. Compared with the single roller method for preparing a tubular support, the device has the advantages that the orderliness of prepared fibers is improved greatly, and the application range of electrostatic spinning is widened.

Description

technical field [0001] The invention relates to the fields of electrospinning and tissue engineering, in particular to preparing ordered tubular scaffolds by applying an external magnetic field. Background technique [0002] Electrospinning technology is widely used in the preparation of nanoscale / microscale fiber materials due to its good controllability, operational flexibility and low preparation cost. The fibers prepared by electrospinning have the characteristics of high specific surface area, excellent mechanical properties, and large porosity, which make them have research and application in the fields of filter materials, tissue engineering materials, electrical and optical materials, and catalyst carrier materials. [0003] Electrospun fiber scaffolds are not only similar to extracellular matrix in shape, structure and size, but also have good mechanical properties, which meet the material requirements of tissue engineering scaffolds, so they are widely used in the ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): D01D5/00
Inventor 李萍张书培牛旭锋李昆樊瑜波
Owner BEIHANG UNIV
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