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Operation suture with function of antibiosis and preparation technology thereof

A technology of surgical suture and efficacy, applied in the field of medical materials, can solve the problems of expensive absorbable sutures, unacceptable to consumers, no sterilization and anti-inflammation, etc., and achieve good biodegradability, good human tolerance, and no inflammatory response Effect

Inactive Publication Date: 2016-02-03
耿文真
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Most of the existing sutures are non-absorbable surgical sutures. Removing the sutures after surgery will bring great pain to the patients, which is difficult for most consumers to accept.
However, at present, absorbable sutures are not only expensive, but also only have the function of sutures without certain bactericidal and anti-inflammatory effects, and it is easy to cause wound infection after use

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Example 1 Surgical sutures with antibacterial effect are prepared from the following main raw materials (80g per serving): 65 parts of chitosan, 9 parts of chondroitin sulfate, 3 parts of indigo, 4 parts of trichosanthes, 6 parts of lantern grass. 3 parts of leaves, 5 parts of orange leaves, 7 parts of baiji, 6 parts of gold everywhere, 6 parts of stachyus, 4 parts of stone butterfly, 5 parts of dry willow, appropriate amount of dicumyl peroxide, appropriate amount of sodium alginate, laurezone Right amount, right amount of menthol.

[0036] The preparation steps of surgical sutures with antibacterial efficacy are as follows:

[0037] (1) Crush the trichosanthemi powder, put it in a container, add rice vinegar, moisten it for 8 hours, take it out, fry it dry, crush it, and pass it through a 140-mesh sieve;

[0038] (2) Crush Mulan, lantern grass, white and dry willow, put them in a container, add rice wine, moisten them for 8 hours, take them out, spread them evenly i...

Embodiment 2

[0047] Example 2 Surgical sutures with antibacterial effect are prepared from the following main raw materials (20g per serving): 78 parts of chitosan, 14 parts of chondroitin sulfate, 6 parts of indigo, 8 parts of trichosanthes, 9 parts of lantern grass, meritorious service 8 parts of leaves, 10 parts of orange leaves, 11 parts of baiji, 9 parts of gold everywhere, 10 parts of stachyus, 7 parts of stone butterfly, 9 parts of dry willow, appropriate amount of dicumyl peroxide, appropriate amount of sodium alginate, lauryl azone Right amount, right amount of menthol.

[0048] The preparation steps of the surgical suture with antibacterial effect are as follows:

[0049] (1) Crush the trichosanthemi powder, put it in a container, add rice vinegar, moisten it for 10 hours, take it out, fry it dry, crush it, and pass it through a 180-mesh sieve;

[0050] (2) Crush Mulan, lantern grass, white and dry willow, put them in a container, add rice wine, moisten for 10 hours, take them...

Embodiment 3

[0060] Example 3 Surgical sutures with antibacterial effect are prepared from the following main raw materials (50g per serving): 70 parts of chitosan, 11 parts of chondroitin sulfate, 4 parts of indigo, 5 parts of trichosanthes, 7 parts of lantern grass, Gong Gong 5 parts of leaves, 7 parts of orange leaves, 9 parts of baiji, 7 parts of gold everywhere, 7 parts of stachyus, 5 parts of stone butterfly, 6 parts of dry willow, appropriate amount of dicumyl peroxide, appropriate amount of sodium alginate, lauryl azone Right amount, right amount of menthol.

[0061] The preparation steps of surgical sutures with antibacterial efficacy are as follows:

[0062] (1) Crush the trichosanthemi powder, put it in a container, add rice vinegar, moisten it for 8 hours, take it out, fry it dry, crush it, and pass it through a 150-mesh sieve;

[0063] (2) Crush Mulan, lantern grass, white and dry willow, put them in a container, add rice wine, moisten for 8 hours, take them out, spread the...

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PUM

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Abstract

The invention discloses an operation suture with a function of antibiosis and a preparation technology thereof. The operation suture is prepared from 65-78 parts by mass of chitosan, 9-14 parts by mass of chondroitin sulfate, 3-6 parts by mass of indigofera tinctoria, 4-8 parts by mass of trichosanthes root, 6-9 parts by mass of peruvian groundcherry herb, 3-8 parts by mass of leaf of Chinese holly, 5-10 parts by mass of tangerine leaf, 7-11 parts by mass of rhizoma bletillae, 6-9 parts by mass of hypericum wightianum, 6-10 parts by mass of Stachys japonica, 6-10 parts by mass of petrocosmea duclouxii, 5-9 parts by mass of salix matsudana, a proper amount of dicumyl peroxide, a proper amount of sodium alginate, a proper amount of azone and a proper amount of menthol. The operation suture with a function of antibiosis is prepared from chitosan with substantial haemostasis effects and good biodegradability and common Chinese herbal medicines by refining, has good antibiosis effects and can effectively prevent operation wound infection.

Description

technical field [0001] The invention relates to the field of medical materials, in particular to an antibacterial surgical suture and a preparation process thereof. Background technique [0002] Surgical sutures refer to special threads used for ligation and hemostasis, suture hemostasis and tissue suture in surgical operations or trauma treatment. Generally, it can be divided into two categories: absorbable sutures and non-absorbable sutures: absorbable sutures are further divided into catgut, chemically synthesized sutures, and pure natural collagen sutures according to the material and degree of absorption. ① Sheep catgut: It is made from healthy animal sheep intestines and contains collagen components, so there is no need to remove the stitches after suturing. The length of time required for absorption depends on the thickness of the gut and the condition of the tissue. Generally, it can be absorbed within 6-20 days, but individual differences in patients affect the abs...

Claims

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Application Information

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IPC IPC(8): A61L17/06A61L17/10A61K36/898A61P7/04A61P31/02A61P17/02A61K31/722A61K31/737
Inventor 不公告发明人
Owner 耿文真
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