Traditional Chinese medicine composition for treating myocardial infarction and preparation method thereof

A technique for myocardial infarction and composition, applied in the field of traditional Chinese medicine composition for treating myocardial infarction and its preparation, can solve the problems of difficulty in popularization and application and high cost of raw materials, and achieve the effects of comprehensive effect, low drug side effects and strong pertinence

Inactive Publication Date: 2016-02-24
叶宗耀
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The traditional Chinese medicine preparation is mainly used to invigorate qi, activate blood circulation, and eliminate phlegm. Combined with western medicine to treat myocardial infarction caused by myocardial ischemia, it ca

Method used

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  • Traditional Chinese medicine composition for treating myocardial infarction and preparation method thereof

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Comparison scheme
Effect test

Embodiment 1

[0046] The traditional Chinese medicine composition of Example 1 of the present invention is mainly prepared from the following raw materials in parts by weight:

[0047] 20 parts of Vitex, 18 parts of Corydalis, 20 parts of safflower, 16 parts of Curcuma, 14 parts of Salvia, 14 parts of Noctilucia, 12 parts of ginkgo leaves, 10 parts of Moringa leaves, 8 parts of scallion, 6 parts of Magnolia officinalis, 6 parts of aconite 10 parts of woody fragrance, 8 parts of Sangjisheng and 8 parts of licorice.

[0048] The preparation method is as follows:

[0049] In S1, Vitex Vitex was crushed, the coarse powder was placed in a supercritical carbon dioxide extraction device, and 30% of the total volume of the above coarse powder was added with ethanol with a volume fraction of 60%. 40 ℃, extraction time is 1.5h, under reduced pressure to obtain Vitex Vitex extract;

[0050] S2 Take Corydalis Corydalis, Salvia officinalis, Magnolia Officinalis Magnolia officinalis, Moringa leaves and...

Embodiment 2

[0054] The Chinese medicine composition of Example 2 of the present invention is mainly prepared from the following raw materials in parts by weight:

[0055] 30 parts of Vitex, 26 parts of Corydalis, 28 parts of safflower, 24 parts of Curcuma, 20 parts of Salvia miltiorrhiza, 22 parts of Nocturne vine, 16 parts of ginkgo leaves, 18 parts of Moringa leaves, 12 parts of scallion, 10 parts of Magnolia officinalis, 12 parts of aconite 16 parts, 16 parts of woody fragrance, 16 parts of Sangjisheng and 18 parts of licorice.

[0056] The preparation method is as follows:

[0057] In S1, Vitex Vitex was crushed, the coarse powder was placed in a supercritical carbon dioxide extraction device, and ethanol with a volume fraction of 40% and 75% of the total amount of the above coarse powder was added, and the flow rate of carbon dioxide was adjusted to 18L / h, the extraction pressure was 16MPa, and the extraction temperature was 50°C, the extraction time is 1.5h, and the extract of Vite...

Embodiment 3

[0062] The Chinese medicine composition of Example 3 of the present invention is mainly prepared from the following raw materials in parts by weight:

[0063] 26 parts of Vitex, 22 parts of Corydalis, 24 parts of safflower, 20 parts of Curcuma, 16 parts of Salvia miltiorrhiza, 18 parts of Nocturne vine, 14 parts of ginkgo leaves, 14 parts of Moringa leaves, 10 parts of scallion, 8 parts of Magnolia officinalis, 8 parts of aconite 12 parts of Muxiang, 14 parts of Sangjisheng and 14 parts of Licorice.

[0064] The preparation method is as follows:

[0065] S1 Take Vitex Vitex and pulverize it, put the coarse powder in a supercritical carbon dioxide extraction device, add 85% ethanol with a volume fraction of 45% of the total amount of the above coarse powder, control the flow rate of carbon dioxide to 20L / h, the extraction pressure to 20MPa, and the extraction temperature to 60°C, extraction time is 2h, and separated under reduced pressure to obtain Vitex Vitex extract;

[006...

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Abstract

The invention belongs to the field of traditional Chinese medicine and relates to a traditional Chinese medicine composition for treating myocardial infarction and a preparation method thereof. The traditional Chinese medicine composition is mainly prepared from, by weight, 20-30 parts of Vitex, 18-26 parts of Rhizoma corydalis, 20-28 parts of Flos carthami, 16-24 parts of Curcuma zedoary, 14-20 parts of Salvia miltiorrhiza, 14-22 parts of Caulis polygoni multiflori, 12-16 parts of Folium ginkgo bilobae, 10-18 parts of leaf of Moringa oleifera, 8-12 parts of Allium macrostemon, 6-10 parts of Mangnolia officinalis, 6-12 parts of Radix aconiti carmichaeli, 10-16 parts of Costus root, 8-16 parts of Herba taxilli and 8-18 parts of Radix glycyrrhiza. The traditional Chinese medicine composition has efficacy of activating blood to dredge collaterals, dispersing stasis to stop pain and activating blood to nourishing heart, has remarkable effect on treating myocardial infarction and is high in clinical popularization and application value.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition for treating myocardial infarction and a preparation method thereof. Background technique [0002] Myocardial infarction refers to the sharp reduction or interruption of coronary blood flow on the basis of coronary artery disease, resulting in severe and persistent ischemia in the corresponding parts of the myocardium and ischemic necrosis. More than 90% of myocardial infarctions are caused by the narrowing of the lumen caused by coronary atherosclerosis. Due to the increase of atherosclerotic plaque, rupture and bleeding, thrombosis or persistent spasm, the lumen is completely occluded and the blood cannot flow. of. Generally, the anterior descending branch of the left coronary artery is most commonly involved, followed by the right coronary artery and the circumflex branch of the left coronary artery. Patients ...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P9/10
Inventor 叶宗耀邹锦新
Owner 叶宗耀
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