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A kind of external Chinese medicinal composition for treating mosquito bites and preparation method thereof

The technology of a composition and traditional Chinese medicine is applied in the preparation of the external Chinese medicine composition, and in the field of the external Chinese medicine composition for treating itching caused by mosquito bites, which can solve the problems of easily causing drug resistance of the body, increasing the burden on patients, skin damage, etc., to achieve The effect of saving treatment costs, remarkable curative effect and reducing waste

Inactive Publication Date: 2019-04-30
INST OF BOTANY JIANGSU PROVINCE & CHINESE ACADEMY OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Current research on itching shows that the conduction pathways of itching include histamine-dependent and non-histamine-dependent itching. Western medicine often treats these itches with antihistamines, anti-inflammatory and analgesic treatments, but these drugs are mostly chemical Synthetics, the general disadvantage is that they are not resistant to antibiotics, which can easily cause drug resistance in the body, and are inconvenient to use. Long-term use will cause damage to the skin, such as pigmentation, allergies and other symptoms, which will increase the burden on patients.

Method used

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  • A kind of external Chinese medicinal composition for treating mosquito bites and preparation method thereof
  • A kind of external Chinese medicinal composition for treating mosquito bites and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0024] An antipruritic traditional Chinese medicine composition for external use, characterized in that it consists of the following raw materials: 15 g of chrysanthemum, 2 g of centipede, 2 g of dried toad skin, 10 g of Dijincao, 10 g of weeping grass, 5 g of peppermint, and borneol 1 g.

[0025] Above-mentioned weeping grass is fresh weeping grass stem and leaf.

[0026] A preparation method of an externally applied traditional Chinese medicine composition for treating itching caused by mosquito bites, the specific steps are:

[0027] (1) Grind Chonglou, Centipede, Dried Toad Skin, Dijincao, Chuipencao, and Peppermint, add deionized water 8 times the weight of the drug, boil on medium heat, decoct on low heat for 1 hour, and filter to obtain For the extract, add deionized water of 8 times the weight of the filter residue, and repeat decocting 3 times;

[0028] (2) Combine the extracts from the three decoctions, carry out vacuum rotary evaporation at 45°C, and concentrate t...

Embodiment 2

[0031] An antipruritic traditional Chinese medicine composition for external use, characterized in that it consists of the following raw materials: 18 g of chrysanthemum, 3 g of centipede, 3 g of dried toad skin, 6 g of Dijincao, 15 g of weeping grass, 8 g of peppermint, and borneol 2 g.

[0032] Above-mentioned weeping grass is fresh weeping grass stem and leaf.

[0033] The preparation method is the same as in Example 1

Embodiment 3

[0034] Embodiment 3 The experiment done by the inventor

[0035] In this study, B6 mice were stimulated with histamine and chloroquine as an animal experimental model of pruritus, and the pharmacodynamics of the antipruritic traditional Chinese medicine composition of the present invention was observed.

[0036] 1 material

[0037] 120 male B6 mice, weighing 25-30 g, were provided by the Experimental Animal Center of Nanjing University of Traditional Chinese Medicine; chloroquine and histamine were all from Sigma. The positive drug is Jidesheng snake tablet.

[0038] The medicine of the present invention is the antipruritic external Chinese medicinal composition prepared in Example 1; the video camera is Sony HDR-CX405.

[0039] 2 methods

[0040] 2.1 Experiment 1

[0041] The antipruritic external Chinese medicine composition of the present invention has a therapeutic effect on histamine-dependent itching. B6 mice are divided into a normal group, a model group, a positive...

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Abstract

The invention discloses an external traditional Chinese medicinal composition for treating pruritus caused by mosquito bites, wherein active ingredients constituting the traditional Chinese medicinal composition mainly include the following raw materials: rhizoma paridis, centipede, dried toad skin, humifuse euphorbia herb, herba sedi, peppermint and borneol. The invention also discloses a preparation method of the traditional Chinese medicinal composition. The external traditional Chinese medicinal composition for relieving itching provided by the invention is simple in preparation method, low in treatment cost, natural in source, scientific in compatibility, rapid to take effect, good in curative effect and free from remarkable toxic and side effects; and the traditional Chinese medicinal composition is mainly used for treating pruritus caused by various mosquito bites.

Description

technical field [0001] The invention relates to an external Chinese medicine composition, in particular to an external Chinese medicine composition for treating itching caused by mosquito bites. The invention also relates to a preparation method of the traditional Chinese medicine composition for external use. Background technique [0002] Mosquitoes are rampant in summer, and people are often bitten by mosquitoes in daily life and field work. After being bitten by mosquitoes, itching, redness, blisters, etc. will occur, affecting daily work and rest. Continuous scratching due to itching can lead to skin ulceration and bleeding in mild cases, and infection and ulceration, scars or allergic reactions can even be life-threatening in severe cases. Therefore, solving various skin itching and redness caused by mosquito bites is the focus of summer disease prevention and treatment. Current research on itching shows that the conduction pathways of itching include histamine-depend...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/896A61P17/02A61P17/04A61K35/648A61K31/045A61K35/65
Inventor 简暾昱陈剑赵磊马丽吕寒童贝
Owner INST OF BOTANY JIANGSU PROVINCE & CHINESE ACADEMY OF SCI
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