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Medicine for preventing and treating porcine reproductive and respiratory syndrome

A technology for respiratory syndrome and pig reproduction, applied in the field of traditional Chinese medicine, can solve problems such as long-term, lack of protection, and inability to stimulate cellular immunity, and achieve the effect of less animal toxicity and less drug residues

Inactive Publication Date: 2016-05-04
QINGDAO HUAREN TECH INCUBATOR
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The main problems of PRRS vaccine clinically are: first, it takes a long time for the vaccine to produce an immune response; second, the PRRSV vaccine does not have complete protection, especially the inactivated vaccine cannot stimulate cellular immunity; third, the attenuated PRRSV vaccine Can exist for several weeks in tissues of immunized pigs and spread from vaccinated to susceptible pigs

Method used

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  • Medicine for preventing and treating porcine reproductive and respiratory syndrome

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0019] The present invention also provides a preparation method of the above-mentioned medicine, which specifically comprises pulverizing the components of each raw material medicine, feeding them into a mixer by weight and mixing them uniformly, adding 500g-600g of water for every 100g of the mixture, boiling for 3-4 hours, filtering, To obtain the first filtrate, add 200g to 300g of water to the filter residue obtained from the 100g mixture, boil again for 1 to 2 hours, filter to obtain the second filtrate, mix the first filtrate and the second filtrate, concentrate to remove the water solvent, pulverize, and dry , to obtain a dry powder.

[0020] The pharmacology of each raw material drug is as follows:

[0021] Epimedii Folium: Latin name Epimedii Folium, spicy, sweet, warm in nature, enters the liver and kidney meridian, has the effect of nourishing kidney yang, strengthening bones and muscles, and dispelling rheumatism. ; Cold-damp arthralgia or spasm and numbness of th...

Embodiment 1

[0049] Embodiment 1 Drug powder 1

[0050] Put Epimedium 25g, Polygonatum 30g, Gorgon 20g, Ephedra 15g, Goose Bubiograss 25g, Shayuanzi 30g, Forsythia 20g, Soil Codonopsis 40g, Water Gardenia 15g, Yam 30g, Moutan Cortex 25g, Baifu Tablet 15g, Tianwen 20g grass, 25g Zhilicorice, 15g Osmanthus fragrans, 20g Osmanthus japonica, 15g Osmanthus fragrans, and 20g Osmanthus fragrans were crushed separately, put into a blender and mixed evenly, for every 100g of the mixture, add 600g of water, boil for 4 hours, filter, Obtain the first filtrate, add 300g of water to the filter residue obtained by the mixture again, boil for 2 hours again, filter to obtain the second filtrate, mix the first filtrate and the second filtrate, concentrate to remove the water solvent, pulverize, dry, and obtain dry powder.

[0051] Pharmacological acute toxicity test

[0052] Experimental animals: SPF grade, Kunming mice, 40 mice, 20±2g, half male and half male, provided by Animal Experiment Center of Qin...

Embodiment 2

[0091] Embodiment 2 Drug powder 2

[0092] Epimedium 23g, Polygonatum 28g, Gorgon 18g, Ephedra 13g, Goose Bubiograss 23g, Shayuanzi 28g, Forsythia 18g, Tudangshen 38g, Water Gardenia 13g, Yam 28g, Moutan Cortex 23g, Baifu Tablet 13g, Tianwen Grass 18g, Radix Glycyrrhizae 23g, Osmanthus fragrans 13g, Miscella 18g, Osmanthus fragrans 13g and Osmanthus fragrans 18g were crushed separately, put into a blender and mixed evenly, for every 100g of the mixture, add 600g of water, boil for 4 hours, filter, Obtain the first filtrate, add 300g of water to the filter residue obtained by the mixture again, boil for 2 hours again, filter to obtain the second filtrate, mix the first filtrate and the second filtrate, concentrate to remove the water solvent, pulverize, dry, and obtain dry powder.

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Abstract

The invention provides a medicine for preventing and treating porcine reproductive and respiratory syndrome. Bulk pharmaceutical chemicals of the medicine comprise herba epimedii, rhizoma polygonati, Gorgon fruit, herba ephedra, small centipeda herb, flatstem milkvetch seed, fructus forsythiae, radix Campanumoeae, fruit of Largeflower Gardenia, rhizoma dioscoreae, moutan bark, white prepared lateral root of aconite, herb of paniculate spotflower, honey-fried licorice root, dichotomy forked fern frond, root of Micromelum integerrimum, herb of Ajuga pantantha Hand.Mazz and herb of Melilotus suavcolen. The medicine has the characteristics of small toxicity to animals and small residue and has more obvious advantages in preventing and treating the porcine reproductive and respiratory syndrome.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a medicine for preventing and treating porcine reproductive and respiratory syndrome. Background technique [0002] Porcine reproductive and respiratory syndrome (Porcine Reproductive and Respira-tion Syndrome, PRRS) is an acute contact infectious disease caused by porcine reproductive and respiratory syndrome virus, which mainly causes reproductive disorders in pregnant sows and respiratory symptoms in piglets, leading to Abortion, stillbirth, mummified fetus, weak piglets and other reproductive disorders and a large number of deaths of piglets. The disease is an acute and highly lethal infectious disease. The virus is highly pathogenic and spreads quickly. The morbidity and mortality of pigs are high. The incidence of piglets can reach 100%, and the mortality rate can reach more than 30%. The rate can reach more than 30%. Fattening pigs and sows can also ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61P31/14
CPCA61K36/296A61K36/11A61K36/17A61K36/28A61K36/34A61K36/48A61K36/481A61K36/484A61K36/53A61K36/62A61K36/634A61K36/71A61K36/714A61K36/744A61K36/75A61K36/8945A61K36/8969A61K2236/331A61K2236/39A61K2300/00
Inventor 孙霞
Owner QINGDAO HUAREN TECH INCUBATOR