Unlock instant, AI-driven research and patent intelligence for your innovation.

Rose-containing traditional Chinese medicine composition for treating obesity and application of rose-containing traditional Chinese medicine composition

A composition and obesity technology, applied in the direction of drug combinations, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve problems such as weight loss effects, addiction, and increased doses

Active Publication Date: 2016-06-22
GANSU DONGFANG TIANRUN ROSE TECH DEV CO LTD
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Phentermine is a short-term anti-obesity drug, but the dose needs to be increased regularly to maintain the effect, suggesting that it has potential addiction
Moreover, the weight loss effect of these three drugs is only 5% higher than that of the placebo group (Zheng et al., 2010; 2014)
Obesity is a chronic disease, so far there is no effective treatment

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Rose-containing traditional Chinese medicine composition for treating obesity and application of rose-containing traditional Chinese medicine composition
  • Rose-containing traditional Chinese medicine composition for treating obesity and application of rose-containing traditional Chinese medicine composition
  • Rose-containing traditional Chinese medicine composition for treating obesity and application of rose-containing traditional Chinese medicine composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] The preparation method of embodiment 1 rose Chinese medicine composition

[0036] Rose 4g, Astragalus 3.91g, Chinese yam 7.82g, Anemarrhena 4.69g, Pueraria 1.31g, Schisandra 2.34g, Trichosanthes 2.34g, Gallinarum 1.56g, add water 100mL, heat to boiling and keep for 30 minutes, dilute to 50mL , sterilized by filtration, and the filtrate was set aside.

Embodiment 2

[0037] The slimming effect of embodiment 2 rose water decoction

[0038] 1. Biological materials:

[0039] (1) Caenorhabditis elegans wild-type strain N2 was purchased from Caenorhabditis Genetics Center (CGC);

[0040] (2) Escherichia coli OP50 (uracil-leakage mutant), purchased from Caenorhabditis Genetics Center (CGC), as food for Caenorhabditis elegans.

[0041] 2. Reagents

[0042] (1) Solid NGM (NematodeGrowth Medium) medium composition and production (take 1 liter as an example):

[0043] Element

content

NaCl

3.00g

K 2 HPO 4

2.34g

K H 2 PO 4

17.23g

Peptone

2.50g

agar

17.00g

Supplement H 2 O to

1000mL

[0044] After the solid NGM medium was prepared, it was sterilized under high pressure at 121°C for 20 minutes, and 1 mL of 10 mg / mL cholesterol, 1 M MgSO 4 1mL, 1M CaCl 2 Shake 1mL well, pour it into a sterilized 9cm culture plate while it is hot, about 20mL / plate. Stan...

Embodiment 3

[0071] The weight loss effect of embodiment 3 Yuye Decoction

[0072] (1) Experimental group settings

[0073] Blank control group (Control): sterile water; Yuye Decoction low-dose group (l); Yuye Decoction medium-dose group (m); Yuye Decoction high-dose group (h).

[0074] Preparation of Yuye Decoction stock solution: 3.91g astragalus, 7.82g yam, 4.69g Anemarrhena, 1.31g kudzu root, 2.34g schisandra, 2.34g trichosanthin, 1.56g chicken gold, add water 100mL, heat to boil and keep for 30 minutes, set Make up to 50mL, sterilize by filtration, and set aside.

[0075] To configure NGM plates containing rose water decoction:

[0076] Take the appropriate dilution of Yuyetang stock solution, add it to the NGM medium, and pour it into the plate.

[0077] The final concentration of Yuyetang is 100-fold dilution, 200-fold dilution, and 400-fold dilution of the initially prepared Yuyetang stock solution. Let stand until the culture medium solidifies. Spread Escherichia coli OP50 ev...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to rose-containing traditional Chinese medicine composition for treating obesity and an application of the rose-containing traditional Chinese medicine composition. The rose-containing Chinese medicine composition has a remarkable treatment function on an obesity pathological model of caenorhabditis elegans and can remarkably reduce fat stored in the caenorhabditis elegans. The rose-containing traditional Chinese medicine composition has a potential in treatment of obesity, can be used for preparation of a medicine for treating obesity and can also be used for health-care products for preparation of health-care products for prevention and adjuvant therapy of obesity.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a rose traditional Chinese medicinal composition for treating obesity and an application thereof. Background technique [0002] The World Health Organization (WHO) announced in 1997 that obesity is one of the world's most important health problems (Xiang Hongding, 2001). Modern medicine has proved that obesity will affect growth and intellectual development, and can cause serious psychological problems. Hypertension, diabetes, hyperlipidemia and other diseases caused by obesity have become killers that threaten human life and health. [0003] The treatment of obesity mainly adopts diet restriction, physical exercise and other lifestyle changes. Obese people can usually lose 22%-25% of their original body weight, but only half of the subjects can lose 5% of their original body weight after three years. %. Surgery is an effective method, but it ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8964A61P3/04A61K35/57
CPCA61K35/57A61K36/428A61K36/481A61K36/488A61K36/57A61K36/738A61K36/79A61K36/8945A61K36/8964A61K2300/00
Inventor 不公告发明人
Owner GANSU DONGFANG TIANRUN ROSE TECH DEV CO LTD