Solid micro-emulsion, preparation method and application thereof

A technology for solid microemulsion and active agent, which is applied in the field of solid microemulsion and its preparation, and achieves the effects of realizing large-scale production, simple preparation process and convenient use.

Active Publication Date: 2016-08-10
广东创美抗衰老研究有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example, Chinese patent ZL99816611.1 discloses a transparent microemulsion, which can maximize the content of moisturizing agent in the composition to improve skin condition and / or improve the spreadability of moisturizing agent on the skin , but still give users a non-greasy feeling

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A solid microemulsion with whitening effect, containing the following components in mass percentage:

[0025] Polysorbate-20 12.5%

[0026] Polyglyceryl-3 Diisostearate 12.5%

[0027] Butylresorcinol 0.5%

[0028] Undecylenoyl Phenylalanine 5%

[0029] Tetrahexyldecyl Ascorbate 5%

[0030] Cetyl Alcohol 3.5%

[0031] Pentaerythritol Distearate 60%

[0032] Modified starch 0.85%

[0033] Cyclodextrin 0.15%.

[0034]Preparation method: 1. Polysorbate-20, polyglyceryl-3 diisostearate, butyl resorcinol, undecylenoyl phenylalanine, tetrahexyldecyl ascorbate, spermaceti Alcohol and pentaerythritol distearate are heated and dissolved to obtain the oil phase; 2. Mix the modified starch and cyclodextrin evenly to obtain a solid phase carrier; 3. Adsorb the oil phase solution on the solid phase carrier and freeze quickly to obtain the mixture 4. Mechanically pulverize the mixed materials to obtain finished products.

[0035] The solid microemulsion with whitening effect ...

Embodiment 2

[0037] A solid microemulsion with anti-aging effect, containing the following components in mass percentage:

[0038] Polysorbate-20 21%

[0039] Polyglyceryl-3 Diisostearate 7%

[0040] Pyridoxine Dipalmitate 1%

[0041] Palmitoyl Tripeptide-1 5%

[0042] Phytosphingosine 6%

[0043] Octyl Methoxycinnamate 10%

[0044] Isododecane 15%

[0045] White Pond Seed Oil 10%

[0046] Modified Starch 20%

[0047] Cyclodextrin 5%.

[0048] The preparation method is similar to Example 1, and will not be repeated here.

[0049] The solid microemulsion with anti-aging effect provided by the present invention was tried continuously for 28 days by 10 personnel, each time in the morning and evening, and it was reported that the facial skin was more delicate, the skin was more compact, and the fine lines were reduced, and no skin irritation and allergies were found. Phenomenon.

Embodiment 3

[0051] A solid microemulsion with anti-acne effect, containing the following components in mass percentage:

[0052] Polysorbate-20 20%

[0053] Polyglyceryl-3 Diisostearate 4%

[0054] Tea Tree Essential Oil 0.1%

[0055] Menthyl Lactate 0.3%

[0056] Ceramides 10.6%

[0057] Isononyl Isononanoate 25%

[0058] Modified Starch 25%

[0059] Cyclodextrin 25%.

[0060] The preparation method is similar to Example 1, and will not be repeated here.

[0061] With the solid microemulsion with anti-acne effect provided by the present invention, 10 personnel tried it out continuously for 7 days, once in the morning and evening, and all reported that the acne disappeared, and no skin irritation and allergies were found.

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PUM

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Abstract

The invention discloses a solid micro-emulsion which comprises: (a) an oil phase, which is composed of one or more oil-soluble cosmetic-effect components; (b) a mixed surfactant, which is composed of one or more non-ionic surfactants; and (c) a mixed carrier, which is composed of one or more water-soluble carriers. The HLB value of the mixed surfactant is the weighted average value of the HLB values of the surfactants in the mixed surfactant, the HLB value of the mixed surfactant being 8-18. The mass ratio of the mixed surfactant to the oil phase is (1:1) - (1:3). The content of the mixed carrier is 1-50 wt% in the solid micro-emulsion. The solid micro-emulsion, compared with conventional micro-emulsions, is higher in content of carried active substances, and is more convenient to store and transport.

Description

technical field [0001] The invention belongs to the field of cosmetics, and in particular relates to a solid microemulsion and its preparation method and application. Background technique [0002] Microemulsion is a new type of functional ingredient carrier for cosmetics developed in recent years. It is composed of oil phase, water phase, surfactant and co-surfactant mixed in a moderate proportion to form a droplet with a particle size between 10-100nm. A transparent or translucent thermodynamically stable oil-in-water or water-in-oil mixed system. [0003] Microemulsions are widely used in the field of cosmetics, and have the characteristics of increasing the solubility of active ingredients, promoting the transdermal absorption of active ingredients, and improving the skin feel of products. For example, Chinese patent ZL99816611.1 discloses a transparent microemulsion, which can maximize the content of moisturizing agent in the composition to improve skin condition and / or...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/06A61K8/97A61K8/37A61K8/68A61K8/64A61K8/49A61K8/34A61K8/42A61K8/67A61Q19/00A61Q19/02A61Q19/08
CPCA61K8/068A61K8/342A61K8/347A61K8/37A61K8/42A61K8/4926A61K8/645A61K8/676A61K8/68A61K8/97A61Q19/00A61Q19/02A61Q19/08
Inventor 黄云薇其他发明人请求不公开姓名
Owner 广东创美抗衰老研究有限公司
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