Method for preparing 5-hydroxymethyl furfural from sugar

Abstract

The invention discloses a method for preparing 5-hydroxymethyl furfural from sugar. The method is characterized in that a hexose is taken as the raw material, and a Levis acid is taken as a catalyst, the hexose is converted into 5-hydroxymethyl furfural in a mixed solvent system of water and gamma-valerolactone at temperature of 50-220 DEG C and the pressure of 0.1MPa-2MPa under the catalysis of the Levis acid. The method has the beneficial effects that the product yield is high, and the process route is simple. The method has potential industrial application prospect.

Description

technical field [0001] The invention relates to a method for preparing chemicals, in particular to a method for preparing 5-hydroxymethylfurfural (5-HMF) from sugar. Background technique [0002] Declining oil resources and global warming require people to look for a green and sustainable energy source to reduce dependence on fossil fuels. 5-Hydroxymethylfurfural (5-HMF) is one of the important platform molecules of biomass, which can be used as a chemical reaction intermediate, a raw material for the synthesis of macrocyclic compounds, and a monomer for polymer materials. It can be further oxidized into a high value-added biomass-based derived fuel. 5-Hydroxymethylfurfural (5-HMF) itself also has pharmaceutical activity, and furan derivatives with different functions (including optical activity, medicine and pesticide, biodegradation and strong coordination ability, etc.) can be prepared. Therefore, the research on the preparation of 5-hydroxymethylfurfural (5-HMF) and it...

AI Technical Summary

Problems solved by technology

[0003] The traditional method of preparing 5-hydroxymethylfurfural (5-HMF) has high requirements on the selection of raw materials, generally limited to fructose, and the direct preparation of 5-HMF from glucose and polysaccharides has low yield and poor selectivity

And the traditional preparation method generally is to react in a large amount of toxic organic solvents such as dimethylsulfoxide (DMSO) (Chheda JN etc.), 1-methyl-2-pyrrolidone, acetonitrile and polyethylene glycol, At the same time, the reaction will generate a large amount of by-product humin

The subsequent development of ionic liquid (ClementLansalot-Matras, etc.) and critical water (Feridoun Salak Asghari, etc.) reaction systems requires high purity of raw materials, serious loss, and high cost

[0004] In recent years, the method that uses inorganic acid (Yusuke Takeuchi etc.) catalyst catalyzed sugars to convert to 5-HMF has also been reported. Although this method is relatively simple and has less investment, it pollutes the environment, corrodes equipment, and is difficult to separate from the product. The existence of a large number of side reactions makes the yield of 5-hydroxymethylfurfural (5-HMF) low

Subsequent methods of using solid base catalysts and solid acid catalysts (Xinhua Qi, etc.) to replace traditional inorganic acid catalysts to prepare 5-HMF also have problems such as difficult preparation, high price, and low stability.

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