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Tablet for treating haemorrhoids and preparation method thereof

A kind of weight and sophora japonicus technology, which is applied in the direction of medical formula, medical preparations containing active ingredients, and devices for making drugs into special physical or taking forms, etc., which can solve the problems of low content of active ingredients, large dosage for patients, and inconvenient Take and other problems, to achieve the effect of stable active ingredients, simple structure, and improve the efficiency of heating and concentration

Inactive Publication Date: 2016-09-28
南京多宝生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The preparation method in the prior art has rough and backward process, many impurities, and low active ingredient content, which leads to excessive dosage for patients and is inconvenient to take, which seriously affects the clinical application of this product

Method used

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  • Tablet for treating haemorrhoids and preparation method thereof
  • Tablet for treating haemorrhoids and preparation method thereof
  • Tablet for treating haemorrhoids and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Take 100g Burnet charcoal, 100g Scutellaria baicalensis, 200g fried Huaijiao, 100g Angelica, 100g fried Citrus aurantium, 100g Fangfeng, 2g tannin, 10g donkey-hide gelatin, add 10 times the weight of medicinal materials in water, soak for 0.5h, decoct for 1 hour, Filter, add water with 8 times the weight of medicinal materials to the dregs, decoct for 1 hour, filter out the medicinal liquid, combine the two decoction liquids, concentrate to 60 ° C relative density is 1.05, add ethanol to make the volume percentage of alcohol content reach 75 %, stirring, standing, filtering, the relative density of the filtrate is 1.25 when the filtrate is concentrated to 65 ° C, and ethanol is recovered to obtain a concentrated solution, refined with a macroporous resin, added to a macroporous adsorption resin column, eluted with 50% ethanol, collected 5 times the column volume of the eluate, recovered ethanol under reduced pressure, concentrated and dried, granulated, compressed into t...

Embodiment 2

[0032]Take 100g Burnet charcoal, 100g Scutellaria baicalensis, 200g fried Huaijiao, 100g Angelica, 100g fried Citrus aurantium, 100g Fangfeng, 2g tannin, 10g donkey-hide gelatin, add 10 times the weight of medicinal materials in water, soak for 0.5h, decoct for 1 hour, Filter, add water with 8 times the weight of medicinal materials to the dregs, decoct for 1 hour, filter out the medicinal liquid, combine the two decoction liquids, concentrate to 60 ° C relative density is 1.05, add ethanol to make the volume percentage of alcohol content reach 75 %, stirring, standing, filtering, the relative density of the filtrate is 1.25 when the filtrate is concentrated to 65 ° C, and ethanol is recovered to obtain a concentrated solution, refined with a macroporous resin, added to a macroporous adsorption resin column, eluted with 50% ethanol, collected 5 times the column volume of the eluate, recovered ethanol under reduced pressure, concentrated and dried, granulated, compressed into ta...

Embodiment 3

[0036] Take 100g Burnet charcoal, 100g Scutellaria baicalensis, 200g fried Huaijiao, 100g Angelica, 100g fried Citrus aurantium, 100g Fangfeng, 2g tannin, 10g donkey-hide gelatin, add 10 times the weight of medicinal materials in water, soak for 0.5h, decoct for 1 hour, Filter, add water with 8 times the weight of medicinal materials to the dregs, decoct for 1 hour, filter out the medicinal liquid, combine the two decoction liquids, concentrate to 60 ° C relative density is 1.05, add ethanol to make the volume percentage of alcohol content reach 75 %, stirring, standing, filtering, the relative density of the filtrate is 1.25 when the filtrate is concentrated to 65 ° C, and ethanol is recovered to obtain a concentrated solution, refined with a macroporous resin, added to a macroporous adsorption resin column, eluted with 50% ethanol, collected 5 times the column volume of the eluate, recovered ethanol under reduced pressure, concentrated and dried, granulated, compressed into t...

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Abstract

The invention provides a tablet for treating haemorrhoids. The preparation method of the tablet comprises the following steps: weighing 100g of carbonized sanguisorba roots, 100g of scutellaria baicalensis, 200g of stir-fried fructus sophorae, 100g of angelica sinensis, 100g of roasted fructus aurantii, 100g of radix saposhnikoviae, 2g of tannin, and 10g of donkey-hide gelatin; adding water which is 10 times weight of the medicinal materials, soaking for 0.5 hour, decocting for 1 hour, and filtering; adding water which is 8 times weight of the medicinal materials into the medicinal material residues, decocting for 1 hour, and filtering the decoction; and preparing the tablet with specific concentrating and drying equipment. The tablet prepared by the method has high content of ferulic acid, and can be applied to preparation of medicines for inhibiting Chinese hamster lung (CHL) cell reproduction.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine extraction, in particular to Zhitejia tablets and a preparation method thereof. Background technique [0002] Zhitejia Tablets can lower serum alanine aminotransferase and can be used for patients with elevated alanine aminotransferase in chronic hepatitis. It has a significant antagonistic effect on liver cell damage, can enhance the ability of liver cells to resist poisons, repair damage and resist mutations, promote the biosynthesis of proteins and glycogen in liver cells, accelerate the rate of amino acid penetration into the human liver, and improve the body's ability to respond The utilization of sugar improves the energy supply of the body and is conducive to the recovery of liver cell function. The preparation method in the prior art has a rough and backward process, many impurities, and low content of active ingredients, which leads to excessive dosage for patients a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/752A61K9/20A61P35/00A61J3/00A61K35/36
CPCA61K36/739A61J3/00A61K9/2004A61K9/2095A61K35/36A61K36/232A61K36/238A61K36/489A61K36/539A61K36/752A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2236/55A61K2300/00
Inventor 李洋
Owner 南京多宝生物科技有限公司
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