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Medicine for treating rheumatism-induced lesions and preparation method thereof

A technology of medicine and myrrh is applied in the field of diseased medicine formulation and preparation thereof, and can solve the problems of lack of treatment effect and the like, and achieve the effects of short course of treatment, high cure rate and treatment of pain symptoms.

Inactive Publication Date: 2016-11-09
刘晓东
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in the follow-up research, the inventor found that although the pharmaceutical formula of this patent can effectively treat rheumatic diseases, the therapeutic effect is still insufficient.

Method used

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  • Medicine for treating rheumatism-induced lesions and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Safflower 8g, Radix Rehmanniae 8g, Frankincense 8g, Polygala 8g, Rhizoma Polygala 8g, Chuanwu 8g, White Snake 15g, Realgar 8g, Forsythia 8g, Angelica 8g, Ephedra 15g, Tripterygium wilfordii 8g, and Sanguis elm 3g.

[0035] Weigh each of the APIs according to the above-mentioned parts by weight and set aside; grind the APIs into powder to obtain a powder mixture; heat the petrolatum to 90°C to melt, then add the powder mixture, stir evenly to obtain a paste mixture, stir evenly to obtain a medium Ointment: smear the Chinese medicinal ointment on the plaster carrier to obtain the Chinese medicinal plaster for external application.

Embodiment 2

[0037] Safflower 8g, Habitat 7g, Frankincense 6g, Polygala 8g, Corydalis 10g, Chuanwu 8g, White Snake 12g, Realgar 10g, Forsythia 8g, Angelica 8g, Ephedra 15g, Tripterygium wilfordii 8g, and Sanguis elm 5g.

[0038] The preparation method is the same as in Example 1.

Embodiment 3

[0040] Comparative test on the effect of treating rheumatoid arthritis

[0041] The following test was used to compare the drug of Example 1 (hereinafter referred to as the drug of the present invention) with the drug of Embodiment 1 of ZL201210528767.2 (hereinafter referred to as the comparative drug):

[0042] Animal grouping and model preparation method: Take male SD rats after 7 days of adaptive feeding, weighing 180-220g, and inject complete Freund's complete adjuvant into the right hindfoot (primary side) under mild ether anesthesia. (Preparation of Freund's complete adjuvant CFA: Take anhydrous lanolin and heat it, measure 4ml, cool it a little, add 6ml of liquid paraffin, grind well and autoclave at 70°C, add 80°C inactivated BCG vaccine per ml for 1h 10mg made) 0.1ml to induce adjuvant arthritis. The swelling degree of the left hind foot (secondary side) of the rat was measured 9 days after CFA inoculation, and the arthritic reaction was observed. The rats with symptoms ...

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Abstract

The invention relates to a medicine for treating rheumatism-induced lesions and a preparation method thereof. The medicine is prepared from safflowers, roots of rehmannia, frankincense, radix polygalae, herbal lycopodii, radix aconiti, long-noded pit vipers, realgar, fructus forsythiae, radix angelica sinensis, herbal ephedrae, common threewingnut roots, radix sanguisorbae and the like. The medicine can be prepared into traditional Chinese medicine patches for external application and has a good treatment effect on rheumatic arthritis and other diseases.

Description

Technical field [0001] The present invention relates to the field of medicine formulations and preparation methods thereof, in particular to a medicine formula for treating pathological changes caused by rheumatism and a preparation method thereof. Background technique [0002] Rheumatoid arthritis belongs to the category of "Arthralgia" in traditional Chinese medicine. It is a clinical manifestation of rheumatic fever. Its etiology and pathology are still unknown. Its typical clinical manifestations are migratory polyarthritis, most of which are symmetrical involvement of large joints such as knee, step, shoulder, elbow and wrist. It is common to transfer from one joint to another. The joints may have redness, swelling, heat and pain. Accompanied by redness, swelling, tenderness around the joints, refusal to press, ring erythema and subcutaneous nodules on the skin. After the pain subsides, no joint stiffness or deformity is left, and joint function can be restored. Traditiona...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61P19/02A61P29/00A61P7/00A61P25/00A61P17/00A61P9/14A61K35/583A61K33/36
CPCA61K36/286A61K33/36A61K35/583A61K36/11A61K36/17A61K36/232A61K36/324A61K36/37A61K36/634A61K36/69A61K36/714A61K36/739A61K36/804A61K2300/00
Inventor 刘晓东
Owner 刘晓东
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