Blood-glucose-lowering traditional Chinese medicine composition as well as preparation method and application

Abstract

The invention discloses a blood-glucose-lowering traditional Chinese medicine composition as well as a preparation method and application. Active components of the blood-glucose-lowering traditional Chinese medicine composition are prepared from a group A and a group B through gradient extraction of 70 percent to 30 percent alcohol-water solution or / and water, wherein the group A is prepared from the following components in parts by weight: 20 to 30 parts of folium mori, 10 to 20 parts of bitter gourds and 10 to 20 parts of radix puerariae; the group B comprises 5 to 15 parts of rhizoma dioscoreae by weight. Pharmaceutically acceptable auxiliary materials are added into the active components to prepare oral preparations including oral solutions, granules, tablets, hard capsules, soft capsules, pills and the like according to a conventional method. A pharmacodynamics test result shows that the blood-glucose-lowering traditional Chinese medicine composition can be used for remarkably lowering blood glucose, glycated hemoglobin (GHb) of experiment rats with type 2 diabetes mellitus and improving oxidative stress indexes, and also has a remarkable blood lipid regulation function and can be used for raising HDL-C (High Density Lipoprotein-Cholesterol) and lowering TC (Total Cholesterol), TG (Triglyceride) and LDL-C (Low-Density Lipoprotein Cholesterol). The active components of the traditional Chinese medicine composition are matched with rice and flour and can be processed into health foods capable of preventing and treating diabetes mellitus, such as porridge, noodles, bread and biscuits.

Description

technical field

[0001] The invention discloses a traditional Chinese medicine composition for lowering blood sugar, a preparation method and application thereof. It involves the fields of traditional Chinese medicine preparation technology and food processing technology. Background technique

[0002] Diabetes (DM) is caused by a variety of pathogenic factors acting on the body, leading to hypofunction of islets, insulin can not play a corresponding regulatory role, and then lead to a series of metabolic disorder syndrome. The highest incidence rates are type 1 diabetes and type 2 diabetes. The clinical manifestations of different types of diabetes are different, and hyperglycemia is their common denominator.

[0003] Type 1 diabetes is mainly manifested by the destruction of pancreatic beta cells and relatively insufficient insulin content, but the body is still sensitive to insulin and requires long-term use of insulin for treatment. The main manifestations of type 2 dia...

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