Traditional Chinese medicine for treating hyperuricemia and preparation method thereof

A technology of hyperuricemia and traditional Chinese medicine, which is applied in the direction of medical formulas, medical preparations containing active ingredients, drug combinations, etc. It can solve problems such as complex prescriptions, achieve good therapeutic effects, have no toxic side effects, and reduce blood uric acid levels Effect

Inactive Publication Date: 2016-11-09
GUANGXI NORMAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The medicines of the above-mentioned inventions all have obvious therapeutic effects on hyperuricemia, but their prescriptions are complex

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Take 60 parts of burdock, 5 parts of Luo Han Guo leaves, 5 parts of Luo Han Guo and 10 parts of dried ginger, mix them into a coarse powder, and extract 3 times in a water bath with slight boiling. The amount of water used for each extraction is 5 times the total amount of raw materials. Extract for 1 hour, collect the extract, concentrate, and dry, add 1000 parts of cyclodextrin to the obtained powder, mix evenly, pack into capsules, and obtain capsules.

experiment example 1

[0026] 1. Li, male, 41 years old, has a family history of hyperuricemia. The medical history has been 12 years. The blood uric acid level is 610umol / L. He usually takes diclofenac sodium or colchicine to control the symptoms. Begin to take the capsule that embodiment 1 makes in October, 2014, every day 1 (equivalent to extract 0.5g), take 30 consecutive days blood uric acid level and drop to 350umol / L.

[0027] 2. Wang, female, 65 years old this year, has a medical history of hyperuricemia for 5 years, blood uric acid level 520umol / L, first gout attack in December 2014, and then began to take the capsules prepared in Example 1, 1 dose per day capsules (equivalent to 0.5g of the extract), taking it for 20 consecutive days, the blood uric acid level dropped to 340umol / L.

Embodiment 2

[0029] Take 65 parts of burdock, 5 parts of Luo Han Guo leaves, 15 parts of Luo Han Guo and 5 parts of dried ginger, mix them into a coarse powder, and extract them twice in a water bath with slight boiling. The amount of water used for each extraction is 6 times the total amount of raw materials. Extract for 2 hours, collect the extract, concentrate and dry, add 500 parts of soluble starch and 500 parts of cyclodextrin to the obtained powder, mix evenly, and press into tablets.

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PUM

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Abstract

The invention discloses a traditional Chinese medicine for treating hyperuricemia. The traditional Chinese medicine is prepared from the following crude drugs in parts by weight: 50 to 80 parts of burdock, 2 to 15 parts of grosvenor momordica leaf, 2 to 15 parts of grosvenor momordica fruit and 5 to 15 parts of dried ginger. Compared with the prior art, the traditional Chinese medicine is prepared only by four types of crude drugs through compatibility, and a synergistic effect of all the crude drugs is achieved, so that the reabsorption of uric acid by kidney tubules can be effectively prevented, the exhausting of the uric acid is increased, and further the level of blood uric acid in a human body is reduced; and the traditional Chinese medicine cannot cause damage to the organs such as liver, stomach, kidney and the like, has no toxic and side effects and is good in treating effect.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine for treating hyperuricemia and a preparation method thereof. Background technique [0002] Uric acid is a product of purine metabolism in the human body. There are two sources of purine in the human body. The endogenous source depends on its own synthesis or nucleic acid degradation (about 600mg / d), accounting for about 80% of the total uric acid in the body; the exogenous source is the ingested purine diet (about 100mg / d), about It accounts for 20% of the total uric acid in the body. Under normal circumstances, the daily production and excretion of uric acid in the human body basically maintains a dynamic balance, and any factors that affect the production and excretion of serum uric acid can lead to an increase in serum uric acid levels. The highest solubility of uric acid in blood is 420 μmol / L. If it exceeds this value, u...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P19/06
CPCA61K36/28A61K36/42A61K36/9068A61K2300/00
Inventor 潘英明杨漓梁东
Owner GUANGXI NORMAL UNIV
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