Calcium carbonate tablets and preparation technology thereof
A preparation process and a technology for calcium carbonate tablets, applied in the field of health food, can solve the problems of low calcium apparent absorption rate and increased bone density, etc.
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Embodiment 1
[0045] prescription:
[0046]
[0047] The particle size of the calcium carbonate is 80nm.
[0048] Preparation:
[0049] (1) Adhesive solution preparation
[0050] Weigh the prescribed amount of hydroxypropylmethylcellulose, disperse and dissolve it with ethanol to obtain the hypromellose ethanol solution; weigh the prescribed amount of starch, disperse it with purified water, add Tween 80, and take another boiling purified water Rush into it quickly to obtain starch paste; pour the hydroxypropyl methylcellulose ethanol solution into the starch paste, stir well and set aside;
[0051] (2) Granulation
[0052] Weigh calcium carbonate, diethyl phthalate, polyethylene glycol 6000, protein sugar and castor oil according to the prescription, put them into the wet granulator together, and mix well; pour the binder solution in step (1) into Mix uniform raw and auxiliary materials, make soft materials, stir, and make granules;
[0053] (3) Drying and granulation
[0054] The...
Embodiment 2
[0060] prescription:
[0061]
[0062] The particle size of the calcium carbonate is 160nm.
[0063] Preparation:
[0064] (1) Adhesive solution preparation
[0065] Weigh the prescribed amount of hydroxypropylmethylcellulose, disperse and dissolve it with ethanol to obtain the hypromellose ethanol solution; weigh the prescribed amount of starch, disperse it with purified water, add Tween 80, and take another boiling purified water Rush into it quickly, obtain starch paste; Wherein, the weight ratio of hydroxypropyl methylcellulose and ethanol is 1:3, and the weight ratio of hydroxypropyl methylcellulose and purified water is 1:4; Pour the ethanol solution into the starch paste, stir well and set aside;
[0066] (2) Granulation
[0067] Weigh calcium carbonate, diethyl phthalate, polyethylene glycol 6000, protein sugar and castor oil according to the prescription, put them into the wet granulator together, and mix well; pour the binder solution in step (1) into Mix uni...
Embodiment 3
[0075] prescription:
[0076]
[0077]
[0078] The particle size of the calcium carbonate is 90nm.
[0079] Preparation:
[0080] (1) Adhesive solution preparation
[0081] Weigh the prescribed amount of hydroxypropylmethylcellulose, disperse and dissolve it with ethanol to obtain the hypromellose ethanol solution; weigh the prescribed amount of starch, disperse it with purified water, add Tween 80, and take another boiling purified water Rush into it quickly, obtain starch paste; Wherein, the weight ratio of hydroxypropyl methylcellulose and ethanol is 1:4, and the weight ratio of hydroxypropyl methylcellulose and purified water is 1:5; Pour the ethanol solution into the starch paste, stir well and set aside;
[0082] (2) Granulation
[0083] Weigh calcium carbonate, diethyl phthalate, polyethylene glycol 6000, protein sugar and castor oil according to the prescription, put them into the wet granulator together, and mix well; pour the binder solution in step (1) in...
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