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Menthol-containing potato starch capsule shell

A technology of potato starch and capsule shell, which is applied in capsule transportation, medical preparations of non-active ingredients, and food forming, etc. It can solve the problems of delayed dissolution of capsule contents, unsatisfactory raw materials, and impact on processing, etc., to improve the taste The effect of astringent feeling, lower product price, and improved palatability

Inactive Publication Date: 2016-12-07
GUIZHOU INST OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In order to reduce production costs, many companies use low-quality blue vitriol skin glue as the raw material for the production of medicinal hollow capsules. Not only the bacteria content seriously exceeds the standard, but also there are high levels of carcinogens such as metallic chromium
In addition, gelatin is easy to cross-link with drugs containing aldehydes, reducing sugar-syl compounds and vitamin C, which makes the water solubility of the gelatin shell worse, leading to the disintegration of the capsule shell and the delay in the dissolution of the capsule contents.
Third, gelatin is also prone to electrostatic charge accumulation under dry conditions, which has an impact on subsequent processing
Fourth, long-term storage in a low-humidity environment will cause gelatin to become brittle and cause capsules to break, etc.
Fifth, due to religious reasons, gelatin capsules are rejected by Muslims, Jews and vegetarians, which is not conducive to the promotion of capsule drugs
[0006] Traditional raw materials cannot meet the above requirements, but the unique function of menthol can solve the problems that traditional materials cannot solve
At present, no relevant literature has been found on capsule shells that use potato starch as the main raw material and contain menthol.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] 1) material preparation

[0020] Weigh main ingredients: potato starch 100g, auxiliary materials: menthol 0.01g, reinforcing agent 20g, plasticizer 1g, food coloring 1g, lubricant 0.1g, disintegrant 2g, surfactant 0.4g, diluent 2g, antibacterial 0.4g oxidant, 1g filler, 0.3g fragrance;

[0021] 2) Disperse the above-mentioned potato starch in 140g of water, heat it to 90°C in a constant temperature magnetic water bath stirring pot, and stir for 15 minutes to obtain a gelatinized glue;

[0022] 3) Add the above-mentioned auxiliary materials into the above-mentioned gelatinized glue, and stir evenly to obtain a dipping glue; ensure that the temperature of the dipping glue is 72-75°C, the temperature of the rubber plate is 45-48°C, and the temperature of the drying tunnel is 62-65°C;

[0023] 4) The glue-dipping solution is subjected to decompression and defoaming treatment, and then the capsule shell is prepared by the glue-dipping method, and dried for 48 hours.

Embodiment 2

[0024] Embodiment 2, each step is the same as embodiment 1; Wherein, menthol 3g, reinforcing agent 5g, plasticizer 3g, food coloring 0.1g, lubricant 2g, disintegrant 0.1g, surfactant 3g, diluent 0.1g , antioxidant 4g, filler 0.2g, flavoring agent 2g; the heating temperature in step 2) is 60°C, and the stirring time is 30 minutes.

Embodiment 3

[0025] Embodiment 3, each step is the same as embodiment 1; Wherein, menthol 1.5g, strengthening agent 12g, plasticizer 2g, food coloring 0.5g, lubricant 1g, disintegrant 1g, surfactant 1.7g, diluent 1g , antioxidant 2.2g, filler 0.6g, flavoring agent 1.1g; the heating temperature in step 2) is 75°C, and the stirring time is 22 minutes.

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PUM

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Abstract

The invention discloses a potato starch capsule shell containing menthol, which belongs to pharmaceutical or food processing; it aims to provide a starch capsule with good palatability, cool taste, antiemetic and antibacterial effects, and increased comfort in the oral cavity and stomach shell. It is prepared from potato starch and auxiliary materials: menthol, enhancer, plasticizer, food coloring, lubricant, disintegrant, surfactant, diluent, antioxidant, filler, flavoring agent: disperse potato starch Heating in water to obtain gelatinized glue; add the auxiliary materials and stir evenly to obtain dipping glue; ensure that the temperature of the dipping glue is 72-75°C, the temperature of the rubber plate is 45-48°C, and the temperature of the drying tunnel is 62-65°C ℃; dip in the glue solution to decompress and defoam, then use the glue dipping method to prepare the capsule shell, and dry for 48 hours.

Description

technical field [0001] The invention relates to a capsule shell, in particular to a capsule shell with potato starch as the main raw material; it belongs to the field of pharmacy or food processing. Background technique [0002] Capsule shell is an egg-shaped hollow shell used to hold solid powder particles. The contents it holds enter the digestive system of the human body together and can be dissolved quickly, reliably and safely; it is mainly used in the fields of medicine and health food, and can solve the problem of Difficult to drink medicine, bad taste, stomach upset. [0003] At present, most widely used capsule shells are processed from gelatin. In order to reduce production costs, many companies use low-quality blue vitriol hide glue as the raw material for the production of medicinal hollow capsules. Not only does the bacterial content seriously exceed the standard, but it also contains high levels of carcinogens such as metallic chromium. In addition, gelatin i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K47/36A61K47/10A61K9/48A23P10/30
CPCA61K9/4816A23V2002/00A23V2200/224A23V2250/5118
Inventor 杨柳涛刘莹
Owner GUIZHOU INST OF TECH
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