Method for preparing titanium/hydroxyapatite biological scaffold through die-free direct-write molding technology

Abstract

The invention provides a method for preparing a titanium / hydroxyapatite biological scaffold through the die-free direct-write molding technology. The method comprises the following steps: the mixed powder of hydroxyapatite powder and titanium metal powder is dispersed into a medium, so as to prepare a titanium / hydroxyapatite ceramic slurry with the solid phase content of 50-80wt percent; a three-dimensional structural map is designed in advance through a CAD software, and then converted to be code language capable of being recognized by a computer, the titanium / hydroxyapatite ceramic slurry is placed into an extruding needle cylinder, under the driving of a three-dimensional platform, the extruding needle cylinder moves along the path appointed by the computer and extrudes for formation layer by layer and simultaneously, therefore, a multilayer ordered three-dimensional porous network-like structure green body is formed; and procedures of drying, sintering and heat treating are performed on the multilayer ordered three-dimensional porous network-like structure green body, and a three-dimensional biological scaffold is obtained.

Description

technical field [0001] The invention belongs to the technical field of medical materials, and in particular relates to a method for preparing a titanium / hydroxyapatite biological scaffold by a moldless direct writing molding technique. Background technique [0002] The composition and physical and chemical properties of hydroxyapatite are similar to the inorganic components of human bones. It has good biocompatibility and bioactivity, and can induce new bone formation. It is a widely used material in inorganic bioceramics. The three-dimensional porous hydroxyapatite structure is widely used in the preparation of biomimetic materials. However, the disadvantages of hydroxyapatite bioscaffolds are high brittleness and low compressive strength, so they can only be used for bone replacement in non-load-bearing parts. [0003] The molding technology of conventional biological scaffolds mostly needs to use laser beam or ultraviolet radiation in the molding process, and it is carrie...

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to provide a method for preparing titanium / hydroxyapatite bioscaffolds by moldless direct writing molding technology, aiming to solve the problem that the molding process of bioscaffolds has high requirements, relatively harsh conditions, and the obtained products are relatively simple, High brittleness and low compressive strength

Images