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III-family nitride biological probe and preparation method thereof

A biological probe and group nitrogen technology, applied in electrical components, circuits, semiconductor devices, etc., can solve problems such as short life, unstable luminescence, and low fluorescence efficiency, and achieve the effects of low cost, high stability, and simple and mature technology

Inactive Publication Date: 2016-12-14
INST OF SEMICONDUCTORS - CHINESE ACAD OF SCI
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  • Abstract
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Problems solved by technology

[0008] The invention provides a group III nitride biological probe and a preparation method thereof, which are used to solve the common problems of existing biological probes such as short lifespan, unstable luminescence, and low fluorescence efficiency

Method used

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  • III-family nitride biological probe and preparation method thereof
  • III-family nitride biological probe and preparation method thereof

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preparation example Construction

[0042] The present invention also proposes a method for preparing a III-nitride biological probe, comprising the following steps: step S1: growing a first n-type gallium nitride layer on a substrate; step S2: growing a first n-type gallium nitride layer on the first n-type gallium nitride layer growing a multi-quantum well layer on the multi-quantum well layer; step S3: growing a second n-type gallium nitride layer on the multi-quantum well layer; step S4: using a chemical etching method to etch the second n-type gallium nitride layer and the multi-quantum well layer, Get the quantum wire structure.

[0043] The chemical solution used for etching is a mixed solution of silver nitrate and hydrofluoric acid, and the chemical etching should be carried out under ultraviolet light.

[0044] The above preparation method also includes immersing the quantum wire structure in a chemical solution to remove the metal particles generated by chemical corrosion, and then ultrasonically clea...

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Abstract

The invention provides an III-family nitride biological probe and a preparation method thereof, and belongs to the crossing field of semiconductor material preparation and biomedicine. III-V family materials with potential application prospects serve as basic materials of the probe, the component, thickness and group number of multiple groups of quantum well material are adjusted to obtain an adjustable quantum wire structure, the requirement that the light emitting intensity and wavelength can be adjusted within certain range can be met, and due to mature preparation technology, the biological probe is highly stable in an organism, tends not to quench, is long in service life, and is metabolic.

Description

technical field [0001] The invention belongs to the interdisciplinary fields of semiconductor material preparation and biomedicine, and in particular relates to a group III nitride biological probe and a preparation method thereof. Background technique [0002] In the medical field, traditional organic dyes and biological nanoprobes are used for cell labeling and fluorescence imaging. [0003] Organic molecules are easy to decompose in vivo, and their fluorescence is easily quenched, so they cannot be tracked and observed for a long time; at the same time, the fluorescent dyes used as acceptors still have poor biocompatibility, low fluorescence quantum yield, insufficient ability to resist photobleaching and Short emission wavelength and other shortcomings, so there are many inconveniences in actual use. [0004] Biological nanoprobes mainly include colloidal gold, magnetic nanoparticles, quantum dots, etc. The signal of nano-gold probes is not easy to amplify on the micro...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): H01L33/06H01L33/32H01L33/00
CPCH01L33/06H01L33/007H01L33/32
Inventor 袁国栋张璐王克超吴瑞伟李晋闽王军喜
Owner INST OF SEMICONDUCTORS - CHINESE ACAD OF SCI
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