The invention discloses a preparation method of a poly-citric-acid-based viscous
composite coating, which comprises the following steps: step 1, dissolving
citric acid, adding
polyethylene glycol and 1, 8-octylene glycol, dropwise adding
acrylic acid, stirring, and sequentially dissolving, dialyzing, purifying and vacuum freeze-
drying to obtain a double-bond poly-citrate
prepolymer; step 2, mixing
polylysine with the double-bond polycitrate
prepolymer to obtain a polycitrate composite solution; step 3, dropwise adding the poly-citrate composite solution to the surface of a matrix, and carrying out thermocuring to obtain a poly-
citric acid-based viscous
composite coating; the invention further discloses application of the poly-
citric acid-based viscous
composite coating.
Acrylic acid is added into a prepared poly-citric acid
prepolymer system to generate a double-bond poly-citrate prepolymer,
polylysine is added to form a poly-citrate composite solution, the poly-citrate composite solution is thermally cured to form the poly-citric acid-based viscous composite
coating with strong
adhesive force, and the poly-citric acid-based viscous composite
coating is suitable for the technical field of degradable biomedical materials.