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Medicinal patch for diminishing skin inflammation, and preparation method thereof

A drug patch and skin technology, applied in the application field of nanometer activated carbon, can solve problems such as easily injuring the liver, kidney, spleen and stomach, affecting the quality of human life, hormone-dependent dermatitis, etc. The effect of strong antibacterial function

Active Publication Date: 2017-01-11
GUIZHOU TELIDA NANO CARBON SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] There are many kinds of dermatological diseases, such as allergic dermatitis, eczema, neurodermatitis, etc. In addition, there are inflammations and infections caused by trauma (burns, cuts, abrasions, etc.). Although skin inflammation is not a serious disease, it does affect the skin. human quality of life
At present, there are many drugs on the market for skin anti-inflammatory and pain relief, most of which are hormone drugs, which can only delay the disease and easily cause hormone-dependent dermatitis; general medical institutions do not have specific drugs and treatments, and it is difficult to relieve the pain as soon as possible, plus the cost High, unbearable; in addition, oral anti-inflammatory drugs, often taken can easily damage the liver, kidney, spleen and stomach

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] A medicinal patch for skin anti-inflammation, the main component is nano activated carbon. The nano-activated carbon is nano-scale activated carbon with a particle size of 1 nm.

[0017] The nano activated carbon is modified with a hydroxyl functional group, and the modification method is: the nano activated carbon is mixed with an ethanol solution with a mass concentration of 20% in a weight ratio of 1:50 and ultrasonically treated to obtain a uniformly dispersed nano activated carbon suspension; With a mass concentration of 15% HNO 3 The solution was oxidized, kept at a constant temperature of 84°C for 20 minutes, and then placed in an ultrasonic processor for ultrasonic treatment. The power of the ultrasonic treatment was 1.05KW, the ultrasonic time was 5min, and the temperature range was controlled at 68°C; finally, it was rinsed with deionized water Wash and filter the pH to 7, and then put it into a vacuum drying oven for drying treatment to obtain nano activated...

Embodiment 2

[0020] A medicinal patch for skin anti-inflammation, the main component is nano activated carbon. The nano-activated carbon is nano-scale activated carbon with a particle diameter of 50nm.

[0021] The nano activated carbon is modified with a hydroxyl functional group, and the modification method is: the nano activated carbon is mixed with an ethanol solution with a mass concentration of 25% in a weight ratio of 1:525 and ultrasonically treated to obtain a uniformly dispersed nano activated carbon suspension; With a mass concentration of 15% HNO 3 The solution was oxidized, kept at 87°C for 27.5 minutes, and then placed in an ultrasonic processor for ultrasonic treatment. The power of the ultrasonic treatment was 1.1KW, the ultrasonic time was 11.5min, and the temperature range was controlled at 70°C; Wash and filter with water until the pH reaches 7, and then put it into a vacuum drying oven for drying treatment to obtain nano activated carbon containing hydroxyl functional ...

Embodiment 3

[0024] A medicinal patch for skin anti-inflammation, the main component is nano activated carbon. The nano-activated carbon is nano-scale activated carbon with a particle diameter of 100nm.

[0025] The nano activated carbon is modified with a hydroxyl functional group, and the modification method is: the nano activated carbon is mixed with an ethanol solution with a mass concentration of 20-30% in a weight ratio of 1:1000 and ultrasonically treated to obtain a uniformly dispersed nano activated carbon suspension liquid; with a mass concentration of 15% HNO 3 The solution was oxidized, kept at 90°C for 35 minutes, and then placed in an ultrasonic processor for ultrasonic treatment. The power of the ultrasonic treatment was 1.15KW, the ultrasonic time was 18min, and the temperature range was controlled at 72°C; finally, it was rinsed with deionized water Wash and filter the pH to 7.5, and then put it into a vacuum drying oven for drying treatment to obtain nano activated carbo...

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Abstract

The invention discloses medicinal patch for diminishing skin inflammation, and a preparation method thereof. The main component of the medicinal patch is nano-active carbon. The nano-active carbon is nanoscale active carbon and the grain size of the nano-active carbon is 1 to 100 nm. A hydroxyl functional group is modified on the nano-active carbon. The preparation method of the medicinal patch comprises the steps: dissolving the nano-active carbon with deionized water so as to form suspension liquid, wherein the mass concentration of the nano-active carbon of the suspension liquid is less than or equal to 1%; shearing non-woven fabric, chemical fiber cloth or silk cloth into cloth with proper size and dipping the cloth into the suspension liquid, wherein the dipping time is 30 to 50 minutes and temperature is maintained to be 20 to 30 DEG C; and performing encapsulation to obtain the medicinal patch. The medicinal patch provided by the invention can effectively diminish inflammation, relieve pain, promote affected part repair or wound healing and treat skin wound infection caused by various reasons, has a strong bacteriostatic function on escherichia coli, staphylococcus aureus and candida albicans which are harmful to a human body, and has high moisture permeability, high air permeability, high oxygen permeability, high safety and no side effects, wherein the bacteriostasis rate can reach not less than 93%.

Description

technical field [0001] The invention relates to the technical field of nano activated carbon application, in particular to a medicinal patch for skin anti-inflammation and a preparation method thereof. Background technique [0002] There are many kinds of dermatological diseases, such as allergic dermatitis, eczema, neurodermatitis, etc. In addition, there are inflammations and infections caused by trauma (burns, cuts, abrasions, etc.). Although skin inflammation is not a serious disease, it does affect the skin. quality of human life. At present, there are many drugs on the market for skin anti-inflammatory and pain relief, most of which are hormone drugs, which can only delay the disease and easily cause hormone-dependent dermatitis; general medical institutions do not have specific drugs and treatments, and it is difficult to relieve the pain as soon as possible, plus the cost High, unbearable; the other is oral anti-inflammatory drugs, often taken easily damage the live...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/44A61K9/70A61K47/36A61P17/00
CPCA61K9/7007A61K33/44A61K47/36Y02A50/30
Inventor 李力
Owner GUIZHOU TELIDA NANO CARBON SCI & TECH
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