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Low-temperature rapid freezing and freeze-drying system

A freeze-drying and low-temperature technology, which is applied in the direction of drying, drying solid materials, and drying solid materials without heating. It can solve the problems of reduced total installed power, extra energy consumption of the system, and inconvenient application, and achieves a large heat transfer coefficient. , miniaturization of equipment, high drying efficiency

Active Publication Date: 2017-01-25
TECHNICAL INST OF PHYSICS & CHEMISTRY - CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, electric heating or steam heating is generally used, resulting in additional energy consumption of the system
[0004] Patent CN101140126B proposes a freeze-drying system using liquid nitrogen refrigeration. Due to the use of liquid nitrogen refrigeration, the required heat needs to be heated additionally during the desorption process, and the source of liquid nitrogen is limited, so the application is inconvenient
Patent CN1987314B proposes a vacuum freeze-drying integrated machine using two-stage compression refrigeration, using the cold source and heat source of the refrigeration compressor unit to cool and heat the material, which can greatly reduce the total installed power. Two-stage compressor with intermediate cooling, and there is no effective recovery of refrigerant return air cooling capacity, and the refrigeration efficiency is limited; at the same time, the system only has a freeze-drying process, no desorption process, and the moisture absorbed in the material cannot be removed

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] see figure 1 It is a schematic diagram of the structure of the ultra-low temperature quick freeze-drying system provided in Example 1 of the present invention for drying streptomycin drugs, and its working method is as follows:

[0031]When the refrigeration cycle system is turned on, the refrigerant enters the high-pressure refrigerant inlet of the first heat exchanger (HX1) 120 at the high-pressure refrigerant outlet of the compressor unit (CU) 110, and the high-pressure refrigerant of the first heat exchanger (HX1) 120 The outlet enters the inlet of the air cooler (AC) 220, enters the high-pressure refrigerant inlet connected to the second heat exchanger (HX2) 130 through the air cooler (AC) 220, and passes through the high-pressure refrigeration of the second heat exchanger (HX2) 130 The refrigerant outlet enters the refrigerant high-pressure inlet of the throttling element (JT) 210, and the refrigerant low-pressure outlet of the throttling element (JT) 210 enters t...

Embodiment 2

[0033] Such as figure 2 As shown, it is the quick-freezing / freeze-drying working mode provided by the second embodiment of the present invention, and its working mode is as follows:

[0034] The low-temperature and low-humidity air A1 passes through the circulation fan (FAN) 240 to form air B1, absorbs the moisture in the air B1 in the drying chamber (DC) 230 to form wet air C1, and the wet air C1 passes through the third valve (V3) 180 to form air D1, after gas-solid separation, and cooling from the third heat exchanger (HX3) 140 to form low-humidity low-temperature air E1, and to form low-temperature low-humidity air after passing through the fourth valve (V4) 190 A1 completes the quick-freezing / freeze-drying cycle: A→B→C→D→E→J→A.

[0035] It can be understood that since the saturated moisture content of air is 3.9×10-4g / kg at -80°C, the quick freezing / lyophilization cycle can remove most of the moisture, remove the remaining adsorbed moisture, and start the desorption dry...

Embodiment 3

[0037] see image 3 , is the desorption drying working mode provided by Embodiment 3 of the present invention, and its working mode is as follows:

[0038] The air A2 at 40°C passes through the circulation fan (FAN) 240 to form B2, absorbs the bound water in the high-temperature air A2 in the drying chamber (DC) 230 to form humid air C2, and the humid air C2 passes through the second valve (V2) After 170, in the fourth heat exchanger (HX4) 150, complete the gas-water separation and cooling process of air state H to I and form air D2, and then form air D2 through the third heat exchanger (HX3) 140 to form air E2, the air E2 passes through the fourth heat exchanger (HX4) 150 to form air F, the air F passes through the first heat exchanger (HX1) 120 to form air G, and the air G passes through the first valve (V1) After 160°C, the high-temperature air A2 is formed to complete the desorption drying cycle, A→B→C→H→I→D→E→F→G→A, and complete the ultra-low temperature quick-freezing a...

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Abstract

The invention provides a low-temperature rapid freezing and freeze-drying system. The low-temperature rapid freezing and freeze-drying system comprise a compressor unit, a first heat exchanger, an air cooler, a second heat exchanger, a throttling component, a third heat exchanger, a circulating fan, a drying chamber, a third valve, a fourth valve and a connection pipeline, wherein the parts form a refrigeration circulation loop, a rapid freezing / freeze-drying circulation loop and a desorption drying circulation loop, so the material can be rapidly frozen and frozen-dried. According to the low-temperature rapid freezing and freeze-drying system, the heat exchanger with refrigeration capacity storage functions are used for storing the refrigeration capacity of the compressor and intensively using the refrigeration capacity of the compressor; the material can be rapidly cooled.

Description

technical field [0001] The invention relates to the technical field of freeze-drying, in particular to a low-temperature quick freeze-drying system. Background technique [0002] Drying is one of the ways to keep things from spoiling. There are many drying methods, such as traditional drying, boiling, drying and spray drying, etc., and these drying methods are carried out at a temperature above 0°C or higher. The products obtained by drying will generally shrink in size and harden in texture, some substances will be oxidized, most of some volatile components will be lost, and heat-sensitive substances such as proteins and vitamins will be denatured, and microorganisms will lose their biological vitality. And the dried substance is not easy to dissolve in water. Therefore, compared with before drying, the product after drying has a great difference in properties. Superheated steam drying has been applied in some countries in recent years, but it is also not suitable for he...

Claims

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Application Information

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IPC IPC(8): F26B5/06F25B1/00F25B41/00F25B41/40
CPCF25B1/00F26B5/06F25B41/28F25B40/06F25B40/02F25B2339/047F25B25/005
Inventor 公茂琼赵延兴郭浩沈俊董学强
Owner TECHNICAL INST OF PHYSICS & CHEMISTRY - CHINESE ACAD OF SCI
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