A kind of biodegradable medical nerve repair catheter and preparation method thereof

Abstract

The invention discloses a biodegradable medical nerve repair catheter and a preparation method thereof and relates to the medical field. The biodegradable medical nerve repair catheter comprises a catheter body, wherein the catheter body comprises an inner tube and an outer tube, and a fibrous membrane layer is arranged between the outer tube and the inner tube and is prepared by mixing silk fibroin fiber and polylactic acid fiber; the inner diameter of the outer tube ranges from 0.5 mm to 1.5 mm, and the wall thickness of the outer tube ranges from 0.01 mm to 0.05 mm; the inner diameter of the inner tube ranges from 0.2 mm to 1.2 mm, and the wall thickness of the inner tube ranges from 0.1 mm to 0.3 mm; the wall thickness of the fibrous membrane layer ranges from 0.1 mm to 0.5 mm; a plurality of vent holes are formed in the outer wall of the inner tube, and the outer tube is made of a porous material prepared from trimethylene carbonate, poly(L-lactide-co-glycolide) and fibroin. Good air permeability and strength of the medical nerve repair catheter can be guaranteed, and the clinical actual requirements can be met. The preparation method is simple, reasonable, time-saving, labor-saving, energy-saving and environment-friendly, and also can guarantee the quality of a terminal catheter.

Description

technical field [0001] The invention relates to the medical field, in particular to a biodegradable medical nerve repair catheter and a preparation method thereof. Background technique [0002] The biodegradable medical nerve repair catheter has good biodegradability and excellent biocompatibility, and can be degraded into small molecular compounds in the body and metabolized, absorbed or excreted by the body. It is used in implantable medical devices, drug slow control In the clinical application of release system and tissue engineering scaffold, there is no need for secondary surgery, which can reduce the pain of patients, simplify the operation procedure, improve the treatment effect, prolong the life of patients and improve the quality of life of patients. Therefore, biodegradable medical nerve repair catheters have been more and more widely used in the field of biomedicine, and have effectively promoted the development of biomedicine and clinical medicine. [0003] How...

AI Technical Summary

Problems solved by technology

[0009] The technical problem to be solved by the present invention is to provide a biodegradable medical nerve repair catheter and its preparation method to solve the problems of poor air permeability and poor strength of the medical nerve repair catheter caused in the prior art. To a large extent, it is difficult to process biodegradable polymers into tubes that can meet the actual clinical requirements, and the preparation process is complicated, and it is difficult to ensure the quality of the terminal catheter.

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