3D printing material for medical bone tissue regeneration, and preparation method of 3D printing material

A 3D printing and bone tissue technology, applied in the field of 3D printing materials, can solve the problems of low mechanical strength, poor water solubility, fast dissolution and absorption, etc., and achieve the effect of good biocompatibility and strong mechanical strength

Inactive Publication Date: 2017-05-31
ZHONGSHAN POLYTECHNIC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Both have very prominent features, but there are also certain defects. For example, the most notable feature of polymethyl methacrylate bone cement is its high mechanical strength, but because of its large amount of heat release during polymerization and the release of residual monomer, etc., often causing a series of complications
[0005] Therefore, it is limited in clinical application; the remarkable advant...

Method used

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  • 3D printing material for medical bone tissue regeneration, and preparation method of 3D printing material
  • 3D printing material for medical bone tissue regeneration, and preparation method of 3D printing material
  • 3D printing material for medical bone tissue regeneration, and preparation method of 3D printing material

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] A 3D printing material for medical bone tissue repair, which consists of:

[0034] (1) Powder material components:

[0035]

[0036] (2) Components of the bonding solution:

[0037]

[0038]

[0039] Production process: (a) Use a dry powder mixer to mix various components of the powder material, and then use a grinder to grind until the particle size is 1-10 microns, that is, the powder material 1# for 3D printing is obtained. (b) Put all kinds of non-aqueous components in the bonding solution into deionized water under the condition of stirring, stir until the system is completely clear and transparent, and finally stand still to prepare the bonding solution 1# for 3D printing.

Embodiment 2

[0041] A 3D printing material for medical bone tissue repair, which consists of:

[0042] (1) Powder material components:

[0043]

[0044](2) Components of the bonding solution:

[0045]

[0046] According to the production process of Example 1, 3D printing powder material 2# and bonding solution 2# were prepared.

Embodiment 3

[0048] A 3D printing material for medical bone tissue repair, which consists of:

[0049] (1) Powder material components:

[0050]

[0051]

[0052] (2) Components of the bonding solution:

[0053]

[0054] According to the production process of Example 1, 3D printing powder material 3# and bonding solution 3# were prepared.

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Abstract

The invention belongs to the field of 3D printing materials, and discloses a 3D printing material for medical bone tissue regeneration. The 3D printing material comprises a powdery material and a cementing solution matched therewith, wherein the powdery material contains the following components in parts by weight: 55-75 parts of tetracalcium phosphate, 65-95 parts of calcium hydrophosphate, 5-20 parts of amorphous silicates, 5-10 parts of fluoride and 5-25 parts of dispersing agent, and the cementing solution contains the following components in parts by weight: 90-100 parts of deionized water, 5-8 parts of sodium hexametaphosphate, 4-6 parts of lecithin, 10-20 parts of surface active agent, 5-10 parts of coagulant, 5-25 parts of binder and 10-15 parts of wetting agent. The invention further discloses a preparation method of the 3D printing material. The printed medical bone tissues not only have strong mechanical strength and compressive property, but also have good biocompatibility, biodegradability and bone conduction and bone regeneration capacity.

Description

technical field [0001] The invention belongs to the field of 3D printing materials, and in particular relates to a 3D printing material for medical bone tissue repair and a preparation method thereof. Background technique [0002] Biofunctional materials, also known as biomaterials, are materials used to interface with biological systems for diagnosis, treatment, or replacement of tissues and organs in the body or to enhance their functions. Direct connection with biological systems is the most basic feature of biomedical materials. Therefore, in addition to meeting certain physical and chemical performance indicators, biomedical materials must also meet biological performance requirements, that is, biocompatibility requirements. This is what distinguishes them from biomedical materials. The most important characteristics of other functional materials. [0003] With the aging of the population and the increase of trauma caused by industry, transportation, sports, etc., the ...

Claims

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Application Information

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IPC IPC(8): A61L27/58A61L27/42B33Y70/00
CPCA61L27/425A61L27/58A61L2430/02A61L2430/12B33Y70/00
Inventor 聂建华陆萱冷小冰
Owner ZHONGSHAN POLYTECHNIC
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