3D printing material for medical bone tissue regeneration, and preparation method of 3D printing material

Abstract

The invention belongs to the field of 3D printing materials, and discloses a 3D printing material for medical bone tissue regeneration. The 3D printing material comprises a powdery material and a cementing solution matched therewith, wherein the powdery material contains the following components in parts by weight: 55-75 parts of tetracalcium phosphate, 65-95 parts of calcium hydrophosphate, 5-20 parts of amorphous silicates, 5-10 parts of fluoride and 5-25 parts of dispersing agent, and the cementing solution contains the following components in parts by weight: 90-100 parts of deionized water, 5-8 parts of sodium hexametaphosphate, 4-6 parts of lecithin, 10-20 parts of surface active agent, 5-10 parts of coagulant, 5-25 parts of binder and 10-15 parts of wetting agent. The invention further discloses a preparation method of the 3D printing material. The printed medical bone tissues not only have strong mechanical strength and compressive property, but also have good biocompatibility, biodegradability and bone conduction and bone regeneration capacity.

Description

technical field [0001] The invention belongs to the field of 3D printing materials, and in particular relates to a 3D printing material for medical bone tissue repair and a preparation method thereof. Background technique [0002] Biofunctional materials, also known as biomaterials, are materials used to interface with biological systems for diagnosis, treatment, or replacement of tissues and organs in the body or to enhance their functions. Direct connection with biological systems is the most basic feature of biomedical materials. Therefore, in addition to meeting certain physical and chemical performance indicators, biomedical materials must also meet biological performance requirements, that is, biocompatibility requirements. This is what distinguishes them from biomedical materials. The most important characteristics of other functional materials. [0003] With the aging of the population and the increase of trauma caused by industry, transportation, sports, etc., the ...

AI Technical Summary

Problems solved by technology

Both have very prominent features, but there are also certain defects. For example, the most notable feature of polymethyl methacrylate bone cement is its high mechanical strength, but because of its large amount of heat release during polymerization and the release of residual monomer, etc., often causing a series of complications

[0005] Therefore, it is limited in clinical application; the remarkable advantage of calcium phosphate bone cement is that its chemical composition is similar to the inorganic components of human bone and has good biocompatibility. However, calcium phosphate bone cement that has entered clinical application still exists. After curing, the mechanical strength is low, the water solubility is poor, the dissolution and absorption are too fast, and the shape cannot be maintained for a long time.

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