Low-cost and high-efficiency curcumin extraction method

An extraction method, curcumin technology, which is applied in the field of low-cost and high-efficiency curcumin extraction, can solve problems such as difficulty in effective separation, and achieve the effects of low cost, easy operation, and high extraction efficiency

Active Publication Date: 2017-06-20
广州市科虎生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] At present, there are many extraction methods for curcumin, and the extraction process also has its own characteristics. Commonly used methods include organic solvent extraction, enzyme extraction, and alkaline water extraction. However, in addition to curcumin, the obtained turmeric extract also contains There are two kinds of curcuminoids, demethoxycurcumin and bisdemethoxycurcumin, which are difficult to separate effectively

Method used

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  • Low-cost and high-efficiency curcumin extraction method
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  • Low-cost and high-efficiency curcumin extraction method

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Experimental program
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Embodiment 1

[0029] A low-cost and efficient method for extracting curcumin, comprising the following steps:

[0030] (1) Grind the commercially available dry turmeric and pass it through a 40-mesh sieve for later use;

[0031] (2) Take crushed dry turmeric and add it to ethanol (75% volume concentration aqueous solution) (the ratio of solid to liquid is 1g:9mL), extract at 55°C for 50min, and at the same time supplement with 45Hz ultrasonic waves to obtain turmeric extract;

[0032] (3) Suction filter the obtained turmeric extract, then concentrate the obtained filtrate until it has no alcohol smell, extract (3 times) with 2 times the volume of petroleum ether (of the concentrated filtrate), discard the petroleum ether layer, and then concentrate Obtain turmeric extract;

[0033] (4) Adding 8 times the weight concentration of 2% sodium hydroxide aqueous solution in the obtained turmeric filter paste, stirring and dissolving, to remove other components such as cellulose, starch, volatile ...

Embodiment 2

[0040]A low-cost and efficient method for extracting curcumin, comprising the following steps:

[0041] (1) Grind the commercially available dry turmeric and pass it through a 40-mesh sieve for later use;

[0042] (2) Take crushed dry turmeric and add it to ethanol (75% volume concentration aqueous solution) (the ratio of solid to liquid is 1g:9mL), extract at 55°C for 50min, and at the same time supplement with 45Hz ultrasonic waves to obtain turmeric extract;

[0043] (3) Suction filter the obtained turmeric extract, then concentrate the obtained filtrate until it has no alcohol smell, extract (3 times) with 2 times the volume of petroleum ether (of the concentrated filtrate), discard the petroleum ether layer, and then concentrate Obtain turmeric extract;

[0044] (4) Adding 8 times the weight concentration of 2% sodium hydroxide aqueous solution in the obtained turmeric filter paste, stirring and dissolving, to remove other components such as cellulose, starch, volatile o...

Embodiment 3

[0051] A low-cost and efficient method for extracting curcumin, comprising the following steps:

[0052] (1) Grind the commercially available dry turmeric and pass it through a 40-mesh sieve for later use;

[0053] (2) Add the crushed dry turmeric to ethanol (70% volume concentration aqueous solution) (the ratio of solid to liquid is 1g:8mL), extract at 50°C for 45min, supplemented by 40Hz ultrasonic wave, and obtain the turmeric extract;

[0054] (3) Suction filter the obtained turmeric extract, then concentrate the obtained filtrate until it has no alcohol smell, extract (3 times) with 2 times the volume of petroleum ether (of the concentrated filtrate), discard the petroleum ether layer, and then concentrate Obtain turmeric extract;

[0055] (4) Add 5 times the weight concentration of 0.5% sodium hydroxide aqueous solution in the obtained turmeric filter paste, stir and dissolve, to remove other components such as cellulose, starch, volatile oil;

[0056] (5) Extract the ...

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Abstract

The invention belongs to the technical field of extraction of plant effective components, and concretely relates to a low-cost and high-efficiency curcumin extraction method. The method sequentially comprises the following steps: taking crushed dry turmeric, carrying out extraction on the crushed dry turmeric by using ethanol, concentrating obtained extraction filtrate, extracting the concentrated filtrate with petroleum ether, re-concentrating the obtained extract, dissolving the obtained concentrate in an aqueous sodium hydroxide solution, extracting the obtained solution with ethyl acetate, and concentrating the obtained ethyl acetate layer to obtain a primary turmeric extract; and dissolving the primary turmeric extract in ethanol, and carrying out high-matching adsorption separation by adopting specially-produced modified attapulgite to respectively obtain a demethoxycurcumin and bisdemethoxycurcumin mixture and highly pure curcumin. The method fully utilizes the structural characteristics of the curcumin and the attapulgite, realizes high matching against the molecular difference, and has the advantages of convenience in operation, no large device demands, high extraction efficiency, low cost, effective separation of the curcumin from the demethoxycurcumin and the bisdemethoxycurcumin, high purity, and realization of industrial production.

Description

technical field [0001] The invention belongs to the technical field of extraction of plant effective components, and in particular relates to a low-cost and high-efficiency extraction method of curcumin. Background technique [0002] Curcumin, the chemical name is: 1,7-bis(4-hydroxy-3-methoxybenzene)-1,6-heptadienedione, the structural formula is shown in formula 1, and it is a rare diketone in the plant kingdom. The active ingredient can be extracted from some plant rhizomes in Zingiberaceae and Araceae. Curcumin is an orange-yellow crystalline powder with a slightly bitter taste and insoluble in water. It is a food additive with high safety. Its function and status are incomparable to any natural plant pigment. It is mainly used in food production for candy, Coloring of beverages, cakes, cold drinks and other foods, especially for protein coloring. In terms of medical applications, curcumin has anti-oxidation, anti-cancer, anti-inflammatory, elimination of free radicals,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C07C45/78C07C45/79C07C45/85C07C49/255
CPCC07C45/78C07C45/79C07C45/85C07C49/255
Inventor 吴海雷史合群庞丽娇
Owner 广州市科虎生物技术有限公司
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