Synthesis method of 3-methoxyl-N, N-dimethylacrylamide

Abstract

The invention relates to a synthesis method of 3-methoxyl-N, N-dimethylacrylamide, and belongs to the technical field of chemical synthesis. The synthesis method comprises the following steps of adding 3-methoxypropionic acid and dimethylamine into a sealed reactor; raising the temperature to 80 to 150 DEG C; performing reaction to obtain 3-methoxyl-N, N-dimethylacrylamide, wherein the pressure in the sealed reactor is 0.1 to 10.0MPa. The 3-methoxypropionic acid is used as the raw materials to perform high-temperature dewatering with dimethylamine in a sealed reaction vessel; polyhydric alcohol and basic catalysts are not needed; the reaction is simple; the implementation is easy; the yield of a product is high; the purity is high; the high yield is realized; meanwhile, the pollution is little; the cost is low; the method conforms to the requirements of modern chemical green synthesis. Meanwhile, the 3-methoxypropionic acid uses low-price acrylonitrile as the starting raw materials; the acrylonitrile is subjected to alkoxylation to obtain methoxyl propionitrile; then, hydrolysis is performed. The operation is simple; the energy consumption is low.

Description

technical field [0001] The invention relates to a synthesis method of a chemical material intermediate, in particular to a synthesis method of 3-methoxy-N,N-dimethylpropionamide, which belongs to the technical field of chemical synthesis. Background technique [0002] 3-methoxy-N,N-dimethylpropionamide (structural formula shown in formula I), is a colorless and transparent solvent, has amide groups and alkyl groups, can be mixed with various solvents, can Highly soluble polymer polyamide; it has the characteristics of high solubility, high permeability, high fluidity, low viscosity, low surface tension, etc., and is not irritating to the skin, safe and environmentally friendly, and can be a good substitute for the traditional solvent N-formazan Pyrrolidone is widely used in electronics, medicine, pesticides, pigments, cleaning agents, insulating materials and other industries. Nowadays, in the increasingly competitive safe solvent market, in addition to solubility, high vol...

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Problems solved by technology

[0007] For example, the Chinese patent (application number: 201380019269.8) discloses a method for the manufacture of β-alkoxypropionamides, in which β-alkoxy acrylates are reacted with amines to produce β-alkoxypropionamides , but this method uses β-alkoxy acrylates as raw materials and reacts with amines. After the reaction, the by-products need to be recovered, and the recovered by-products contain a large amount of amines, so it is difficult to handle, and the raw materials themselves are processed by acrylic acid. Obtained from esterification and methoxidation, the process is relatively cumbersome and the energy consumption is high

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