62results about How to "Simple response" patented technology

The invention discloses a pH-stimulation response type intelligent nanometer container and a preparation method thereof. The method comprises the following steps of preparing mesoporous silica microspheres; performing dealcoholization on the dried mesoporous silica microspheres and an alkynyl-containing silane coupling agent in dried methylbenzene; preparing 2-bromo-ethyoxyl-2-azido radical-ethyoxyl propane; after the product obtained through dealcoholization is dried in vacuum, performing click chemical reaction on the product, excessive 2-bromo-ethyoxyl-2-azido radical-ethyoxyl propane and the dried N,N-dimethyl formamide to generate a five-membered ring; after the obtained product is dried in vacuum, dispersing the product in a buffer solution of NaH2PO4/Na2HPO4 which contains absorbed molecules, adding amino-beta-cyclodextrin into the buffer solution, and performing substitution reaction to obtain the final product, i.e. the PH-stimulation response type intelligent nanometer container. The pH-stimulation response type intelligent nanometer container provided by the invention is high in sensitivity to pH and simple and convenient in response operation; automatic opening/closing of a valve can be realized; releasing of molecules absorbed in the nanometer container is promoted; the pH-stimulation response type intelligent nanometer container has a good application prospect.

The invention relates to a method for directly preparing stannous methanesulfonate through electrolytic method, which is characterized in that the electrolytic method is adopted to directly obtain the stannous methanesulfonate water solution, wherein, at least the positive electrode of the electrolysis negative electrode, positive electrode is the solid tin, the positive electrode and the negative electrode are separated through an ion exchange membrane, the electrolyte is the methylsulfonic acid water solution. Compared with the chemical synthesis, the preparation method provided by the invention has simple process, and the reaction is easy to control, the reaction speed is fast, the production period is short; compared with the stannous chloride method, the impurity content of the obtained product is less, the further separation and purification are not required, the post-processing is simple; through controlling the concentration of the electrolyte and the solid purity, the stannous methanesulfonate water solution of required purity, concentration can be directly obtained at one step.

The invention relates to a method of extracting the casein from milk, comprising the following steps of pre-treating the milk, and separating and defatting the pretreated milk to obtain dilute butterand defatted milk; sterilizing and acidizing the defatted milk to obtain casein precipitate and whey; and washing, dewatering, smashing and drying the casein precipitate. The invention also provides amethod of producing lactic acid beverage by dispersing dilute butter which is obtained from the casein production into the whey through surfactant and then adding various additives. The invention hasthe characteristics of easy reaction, little power consumption, low cost, high purity of extracted casein and the like.

The invention discloses a method for synthesizing MoO3 nanometer photochromic powder, which comprises the following steps of: (1) confecting molybdate precursor solution; (2) regulating system pH value; (3) transferring into a hydro-thermal reaction kettle to carry out hydro-thermal reaction; and (4) washing and collecting powder. The method uses the hydro-thermal method to synthesize photochromic MoO3 nanometer powder, and the synthesized powder can absorb sunlight or uviol lamp light and the like irradiation light, generate obvious photochromism and can fade under normal nonluminous conditions.

The invention provides a polysiloxane polymer and a preparation method thereof. The polysiloxane polymer is shown in formula (I). The preparation method of the polymer comprises the following step: carrying out ring-opening polymerization reaction on methyl hydrogen cyclosiloxane and methyl vinyl cyclosiloxane, or methyl hydrogen cyclosiloxane, methyl vinyl cyclosiloxane and monomer A in the presence of organic silicon blocking agent and cationic polymerization initiator, thus obtaining the polysiloxane polymer, wherein the monomer A is dimethyl cyclosiloxane, methyl phenyl cyclosiloxane or R'-substituted methyl hydrogen cyclosiloxane; R' is methyl, phenyl, CH2CH2Ph, CH2CH2CN, CH2CH2CO2CH3, CH2CH2CO2C4H9, CH2CH(CH3)CO2CH3 or CH2CH2OR''; and R'' is C1-20 alkyl, cycloalkyl, ether or alcohol.

The invention relates to a synthesis method of 3-methoxyl-N, N-dimethylacrylamide, and belongs to the technical field of chemical synthesis. The synthesis method comprises the following steps of adding 3-methoxypropionic acid and dimethylamine into a sealed reactor; raising the temperature to 80 to 150 DEG C; performing reaction to obtain 3-methoxyl-N, N-dimethylacrylamide, wherein the pressure in the sealed reactor is 0.1 to 10.0MPa. The 3-methoxypropionic acid is used as the raw materials to perform high-temperature dewatering with dimethylamine in a sealed reaction vessel; polyhydric alcohol and basic catalysts are not needed; the reaction is simple; the implementation is easy; the yield of a product is high; the purity is high; the high yield is realized; meanwhile, the pollution is little; the cost is low; the method conforms to the requirements of modern chemical green synthesis. Meanwhile, the 3-methoxypropionic acid uses low-price acrylonitrile as the starting raw materials; the acrylonitrile is subjected to alkoxylation to obtain methoxyl propionitrile; then, hydrolysis is performed. The operation is simple; the energy consumption is low.

The invention relates to a preparation method of a Mg-doped lithium nickel cobalt aluminum oxide positive electrode material. The method comprises the following steps: 1, preparing a Mg-doped spherical nickel cobalt aluminum hydroxide precursor through a coprecipitation technology; and 2, individually carrying out preoxidation calcining treatment on the Mg-doped spherical nickel cobalt aluminum hydroxide precursor to obtain a high-valence spherical Mg-doped nickel cobalt aluminum oxide uniform solid solution, mixing the a high-valence Mg-doped nickel cobalt aluminum oxide with a lithium source, carrying out high temperature calcination in oxygen atmosphere, cooling the obtained calcination product, and crushing the cooled calcination product to obtain the Mg-doped lithium nickel cobalt aluminum oxide positive electrode material. The lithium nickel cobalt aluminum oxide positive electrode material prepared through the method has the characteristics of high energy density, low cost, simple preparation technology, and easiness in realization of industrialization, and has greatly better battery specific capacity, rate and other cell performances than Mg-free materials.

The invention provides a preparation method of glyphosate zinc, which comprises the following step: heating glyphosate and a zinciferous compound in a solution to react to obtain the glyphosate zinc, wherein the zinciferous compound is selected from one or more of zinc oxide, zinc carbonate, zinc hydroxide and basic zinc carbonate. The glyphosate and zinciferous compound directly react to obtain the glyphosate zinc instead of reaction after previously generating sodium salt; and thus, the method is simpler in reaction, does not need to treat abundant sodium-containing wastewater, and is more environment-friendly. The glyphosate content in the prepared mother solution is low, and the glyphosate zinc yield is high.

The invention relates to a method for preparing a high quality Antarctic krill oil rich in phosphatidylserine containing polyunsaturated double-bonded fatty acyl. The method comprises the following steps: 1) carrying out solvent extraction on existing Antarctic krill oil to obtain phosphatidylcholine and oil containing vitamin A, vitamin E and astaxanthin; 2) preparing an enzyme catalysis reaction system, which is an aqueous phase reaction system; 3) adding the reaction system into a reactor, adding phospholipase D and carrying out mechanical agitation continuously; 4) extracting obtained reaction repeatedly and carrying out freeze drying on filtered solid to obtain phosphatidylserine rich in polyunsaturated double-bonded fatty acyl; 5) mixing the obtained phosphatidylserine rich in polyunsaturated double-bonded fatty acyl with the oil obtained in the step 1) to obtain the high quality Antarctic krill oil. The invention also provides a method for preparing phosphatidylcholine rich in polyunsaturated double-bonded fatty acyl from existing Antarctic krill oil and a method for preparing phosphatidylserine rich in polyunsaturated double-bonded fatty acyl.

The invention relates to a damper for a skip bucket guide wheel support. The damper comprises a tubular outer adjusting sleeve, a tubular inner adjusting sleeve arranged in the outer adjusting sleeve, a guiding sleeve with the two open ends, and a damping guide column matched with an inner cavity of the guiding sleeve. The inner adjusting sleeve and the outer adjusting sleeve are movably connected. A cover cap is movably connected with the guiding sleeve. At least four symmetrically distributed axial sliding grooves are formed in the side wall of the guiding sleeve. A first spiral spring is arranged in an inner cavity of the cover cap. Sliding rods matched with the sliding grooves are arranged at the head end of the damping guide column. An annular piston matched with an inner cavity of the inner adjusting sleeve, and a second spiral spring matched with the damping guide column are further arranged in the inner adjusting sleeve. The damper for the skip bucket guide wheel support is easy to use, the adjusting gap of the damper can reach 60-150 mm, and the damper is high in comprehensive utilization rate, convenient and rapid to mount and maintain, good in damping effect, sensitive in buffer damping action, high in response speed, good in implementation effect and high in application value.

The invention relates to a method for visually detecting nucleic acid, which is a method by adopting nucleic acid as target and connecting magnetic beads and gold nano-particles by chemical self-connection reaction. According to the method, the reaction condition is controlled, a connecting probe complementary with the target nucleic acid part is respectively modified on surfaces of magnetic beadsand gold nano-particles, and the magnetic beads and gold nano-particles are connected by a self-connection reaction after matching with the target nucleic acid; the gold nano-particles which do not react are removed through magnetic separation, and visual detection on nucleic acid can be carried out through magnetic separation. The separation method is convenient, and materials are partially commercialized with high biosafety.

The invention relates to a synthesis process of dibenzofuran derivatives, and relates to the fields of natural products with biological activity, medicaments and material chemistry. The used raw material is a cyclic diphenyliodonium trifluoromethanesulfonate derivative, a reaction is carried out in a water phase at 100 DEG C under the catalysis of a 1,10-phenanthroline ligand and cuprous iodide, and a series of dibenzofuran derivatives are obtained. With the adoption of the method provided by the invention, the dibenzofuran derivatives can be obtained by carrying out the reaction at the temperature of 100 DEG C for 24 hours, and the yield is 60-96%. In the reaction, water is taken as a reagent as well as a solvent for participating in the reaction, and the simple, convenient, green, economic, and novel method is provided for synthesizing the derivatives.

The invention discloses an azoxystrobin synthesis method. The method is characterized in the steps of a, 3-(alpha-methoxy)-methylenebenzofuran-2(3H)-one and excessive sodium methoxide are subjected to a reaction; an organic acid or organic acid anhydride is added for neutralizing excessive sodium methoxide; and a reaction liquid is obtained; b, under an alkaline condition, 4,6-dichloropyridine is subjected to a coupling reaction with 2-hydroxybenzonitrile or a salt thereof, and a reaction liquid is obtained; c, the reaction liquid obtained in the step b is subjected to a reaction with the reaction liquid obtained in the step a under the existence of a catalyst; desalination is carried out when the reaction is finished, metal chloride is added, and a reaction is carried out under heating; and post-treatment is carried out, such that azoxystrobin is obtained. The method has mild reaction conditions. According to method, the production of a byproduct 4-chloro-6-methoxy pyrimidine caused by the reaction of the excessive sodium methoxide and 4,6-dichloropyrimidine in a traditional method can be avoided, and the production of disubstituted products can be avoided. An olefination reaction can be carried out under normal pressure or negative pressure, and highly toxic catalysts such as dimethyl sulfate are not used in the reaction process, such that safety is greatly improved, and environment pollution is greatly reduced. The reaction is pure, and less byproducts are produced.

The invention discloses an enzymatic preparation method of L-theanine by utilizing L-glutamine-Copper (II) complex as donor, which comprises that adopting chemical process to synthesize L-glutamine-Copper (II) complex and Gamma-glutamyltranspeptidase is added into the mixed aqueous solution of containing substrate of L-glutamine-Copper (II) complex and ethylamine for reaction. The method has the advantages of avoiding auto-transpeptidation problem, greatly promoting the conversion rate of donor, realizing the simple operation and the mild reaction condition as well as the low cost.

The invention provides a mixed solution of carbonate and caustic alkali for preparing monocrystal silicon suede, relating to the technical field of preparation of solar cells, in particular to the preparation of the suede in manufacturing technique of monocrystal line silicon solar cells. The formulation comprises the components of carbonate, caustic alkali and isopropanol. When the etchant solution of the invention is used for preparing the monocrystal line silicon suede, reaction can be controlled easily, the pyramid uniformity of the prepared suede is good, and the surface consistency of silicon chip is good. Moreover, when the etchant solution of the invention is used for preparing the monocrystal line silicon suede, the invention has the characteristics of low cost and easy operation, can be applied to large-scale industrial production, and has favorable practical value.

The invention discloses a making method of powder-shaped, insoluble, water, urine or blood absorbable, low-nonreacted monomer high-hydroscopicity resin, which comprises the following steps: feeding polybasic epoxy radical compound with high-hydrophilicity and long-chain with neutralizing rate over 50% and reacting starter protected by nitrogen in the reactor continuously; generating gel on the bottom of groove; starting sealed mechanism on the groove bottom; anchoring gel to move downwards through rod; cutting the gel; drying; grinding; sieving; coating surface crosslinking agent; heating surface at 90-230 deg.c.

The invention relates to a method for recycling valuable metal in a lithium ion battery, and belongs to the technical field of battery recycling. The method for recycling the valuable metal in the lithium ion battery is low in cost. The method comprises the following steps: disassembling the lithium ion battery, removing a shell, and smashing an inner core to obtain cathode and anode powder; adding an ignition agent into the cathode and anode powder, igniting the ignition agent to initiate a reaction, after the reaction is stable, introducing oxygen-enriched gas and oxygen-deficient gas, afterthe reaction continues to be completed, removing upper slag, and cooling lower liquid to obtain a metal mixture. According to the method, only the battery shell and a diaphragm need to be removed, raw materials are obtained rapidly, the cathode and anode powder does not need to be separated, the raw materials in the lithium ion battery are fully utilized for the reaction, a reducing agent and a heat source do not need to be additionally added, and the reaction is simple and rapid. The metal mixture obtained after the reaction is high in purity, and the content of acid-insoluble impurities islower than 1%.

The invention discloses a process for preparing octenal by a one-pot method, which relates to the field of organic synthesis. The process comprises the following steps: (1) placing alkaline dual effect rhodium catalysts and solvents into an autoclave; introducing propylene after water removal and oxygen removal, wherein the propylene ingredient pressure in the reaction system is between 0.5 and 2.0MPa, and the consumption ratio of the alkaline dual effect rhodium catalysts to the solvents is between 0.001 and 0.1g/ml; and (2) introducing synthesis gas to obtain the synthesis gas ingredient pressure between 0.01 and 2.5MPa, and heating the materials to 70 to 200 DEG C, stirring the materials at 500 to 1000 rpm for reaction, wherein the reaction product dwell time is between 0 and 6hr. The alkaline dual effect rhodium catalysts in the first step use mesoporous molecular sieve as carriers, and have metal bits and alkaline bits, the metal bits are rhodium phosphine complex compounds, and the alkaline bits are organic amine. The process has the advantages that the reaction which can be only completed through two reaction vessels in the prior art can be completed in one reaction vessel, the reaction is simpler, the process is shorted, the subsequent process steps are reduced, the reaction product processing is simplified, and the invention has the advantages of easy separation, cost reduction and energy source saving.

The invention discloses a method for preparing cyclohexanone glycol ketal compounds. The method is characterized in that fly ash is directly used as a catalyst to catalyze the condensation dehydration reaction of cyclohexanone compounds and glycol compounds to obtain the cyclohexanone glycol ketal compounds. The fly ash is directly used as the catalyst for synthesizing cyclohexanon eglycol ketal through the condensation of clohexanone and glycol without any treatment; the fly ash is cheap and easily available; the problem that solid catalysts are difficult to industrialize due to low cost performance and the environmental problems brought by the fly ash are solved to some extent; compared with the prior art in which an ammonium persulfate-modified fly ash catalyst is used, the method has the advantage that the yield is higher when fly ash is directly as a catalyst for catalyzing the condensation dehydration reaction of 4-tert-butyl cyclohexanone or cyclohexandione and the glycol compounds.

The invention relates to a method for preparing a prasugrel intermediate with a one-pot method. The method comprises the following steps of: synthesizing 2-(2-fluorophenyl)-N-methoxyl-2-(methoxymethoxyl)-N-methylacetamide or 2-(2-fluorophenyl)-N-methoxyl-N-methylacetamide by taking 2-(2-fluorophenyl)-2-(methoxymethoxyl)acetic acid or fluorophenylacetic acid, PCl3 and NH(CH3OCH3) as raw materials with a one-pot method; and directly reacting with cyclopropylmagnesium bromide serving as a Grignard reagent to obtain 1-cyclopropyl-2-(2-fluorophenyl)-2-(methoxymethoxyl)ethyl ketone or 1-cyclopropyl-2-(2-fluorophenyl)ethyl ketone serving as a target product. According to the method, the problems of instability and difficulty in preparing of phosphoramidite existing in the prior art are solved, a reaction is simplified greatly, and the reaction period is shortened greatly; and meanwhile, adopted raw materials and reagents are cheap and readily-available, the cost is low, a single product is obtained, a post-treatment process is simple, the yield is high, and good conditions are created for industrial mass production and commercialization of a product.

The invention provides a method for preparing hydroxyl ester. The hydroxyl ester is reduced and synthesized by taking 4-chloracetyl acetidin as a raw material and taking sodium borohydride as a reducing agent in an alkaline environment. According to the method for preparing the hydroxyl ester provided by the invention, the cost is low; the reaction is easy to control; the yield is above 80%; and the purity is above 95%.

The invention relates to a novel pearlescent pigment which takes aluminum nitride as a cladding layer. The cladding layer is plated on the surface of a matrix layer through a reactive sputtering technology. Metal aluminum with the purity higher than 98 percent is used as a sputtering target; the sputtering current is 7 to 10A and the sputtering time is 20 to 60min; nitrogen gas with the purity higher than 99 percent is used as reaction gas and the volume flow ratio of the nitrogen gas to argon gas is 0.25 to 1. The novel pearlescent pigment provided by the invention has the beneficial effectsthat (1) the novel pearlescent pigment is green and environmentally friendly; (2) the cost is reduced; (3) the wear resistance is good; (4) the stability is good.

The invention discloses a method of preparing a tryptopquinoline heterocycle by carrying out a heating reaction on anthranil and 4-hydroxyl coumarin. The reaction comprises the following steps: dissolving anthranil and 4-hydroxyl coumarin in a solvent, and carrying out a reaction on the reaction mixture at 150-300 DEG C for 0.2-5 hours; and stopping heating, cooling the reactant to room temperature, adding water, extracting the reactant with a solvent, evaporating the reactant, carrying out purification by a column chromatography to obtain the tryptopquinoline heterocyclic compound. The preparation method is the reaction of anthranil and 4-hydroxyl coumarin in a thermal promoting condition. Catalysts and additives are not needed for the conversions, few byprodcuts are available, and the preparation method is a novel method of constructing the tryptopquinoline heterocyclic compound quickly.

The invention provides a method for preparing Ni-Fe/Fe compound powder film with high magnetic conductivity. The method comprises the following steps of: adding iron salt and nickel salt to ethylene glycol, adjusting the pH value, heating and stirring the solution till the iron salt and the nickel salt dissolve completely, adding K2PtCl14, heating the mixed solution to the temperature of between 150 and 200 DEG C, keeping temperature constant for 30 to 180 minutes to perform synthesis reaction to obtain suspended solution, cooling the suspended solution to the room temperature, centrifuging the suspended solution and removing liquid phase to obtain a solid phase which is Ni-Fe micro particles; and mixing the Ni-Fe micro particles and micro-level Fe powder to obtain the compound magnetic powder. The compound magnetic powder is coated on a basal body, the basal body coated with the compound magnetic powder is applied with magnetic fields and dried, and the compound magnetic powder film is obtained on the basal body, wherein the thickness of the film is 10 to 1,000 mu m. The synthesis method has the advantages that: the method is simple and easy to operate, non-poisonous and harmless, and does not cause environmental pollution; the obtained Ni-Fe/Fe compound magnetic powder film possesses high saturation magnetization, low coercive force and controllable magnetic conductivity, is a good type of soft magnetic materials and has wide application prospect in fields such as high-frequency electromagnetic noise inhibition of an integrated circuit, design of a DC-DC converter, wave-absorbing materials and the like.

The invention discloses a damage-proof automobile front hood supporting frame which comprises a trapezoidal body, supporting frame handles, limiting blocks and a positioning block. Supporting legs are mounted on the lower surface of the first edge of the trapezoidal body, elastic materials are connected to the lower portions of the supporting legs, and the elastic materials are prepared from an epoxy composition and a carbonic ester composition. The epoxy composition is composed of bis(2,3-epoxy cyclopentyl)ester, adipic acid bis(3,4-epoxy-6-methyl cyclohexyl formic acid), bis(4-amino-3-methyl cyclohexyl)methane, glass beads and methacrylic acid. The carbonic ester composition is composed of dinaphthyl, dicyclohexyl carbonic ester, mica, dyhydroxyl polydiethylsiloxane, amine phosphate and N-hydroxymethyl acrylamide. The damage-proof automobile front hood supporting frame is arranged on an automobile front cabin body and stabilized through the supporting legs and supporting feet, the supporting legs are located above automobile headlamps, the position of the supporting frame can be moved through the supporting frame handles, and the limiting blocks and the positioning block are matched to guarantee that a front hood is mounted in place.

The invention discloses an organic silicon resin conformal coating capable of being cured at room temperature and a preparation method thereof. The organic silicon resin conformal coating capable of being cured at room temperature is mainly prepared from the following raw materials: hydroxymethyl organic silicon resin, alkoxy-terminated phenyl silicone oil, a cross-linking agent and a catalyst. The organic silicon resin is modified in the invention to obtain the organic silicon resin conformal coating introduced with a bifunctional chain link, so the toughness of the silicon resin is improved;and the organic silicon resin conformal coating contains the tin catalyst, so the curing of the coating at room temperature is realized.

The invention relates to a method for synthesizing n-propylbenzene through a Grignard reagent method. The technical scheme comprises that in an ether solvent, benzyl chloride reacts with magnesium powder or magnesium strip to produce a benzyl magnesium chloride Grignard reagent, and the benzyl magnesium chloride Grignard reagent reacts with an ethylation reagent to produce n-propylbenzene. Compared with the method in the prior art, the method for synthesizing the n-propylbenzene by using the Grignard reagent method in the present invention has the following advantages that (1) the reaction is simple, the used reagents are less, and the operation is easy; (2) the pollutants are less, and the method does not produce a lot of aluminum-containing wastewater; (3) the reaction temperature is low and is usually not more than 100 DEG C, the energy consumption is low, and the method does not required the heating evaporation of a large amount of water in the F-C method; and (4) the raw materials are easy to obtain, the yield is high, the side effects are less, and the production cost is low.

The invention relates to a synthesis method of Daclatasvir. The method comprises the following steps: step 1, performing a bromination reaction on 4.4-diacetyl biphenyl which serves as a raw material so as to obtain an intermediate 1; step 2, performing a substitution reaction on the intermediate 1 so as to obtain an intermediate 2; step 3, performing a cyclization reaction on the intermediate 2 so as to finally obtain the Daclatasvir. Compared with reported synthesis routes, a synthesis route of the method has the following advantages that the route is short, and the yield is high; general means such as suction filtration, extraction and concentration are adopted for aftertreatment, and aftertreatment is simple and convenient; severe-pollution and high-toxicity reagents such as bromine are avoided, and a process of repeatedly using an acetic acid washing reaction system is avoided.

This invention discloses n,n'-bi(inter cresyl) urea water phase high pressure preparation method. 1) m-toluidine is mixed with water, then mineral acid is added for salifying reaction, then urea is added and agitated, there equivalence ratio is 1:0.95-1.05, mol ratio of the m-toluidine and urea is 1:0.5-1, the salifying reaction temperature is 0-80 degree centigrade. 2) the reaction liquor above is added into high pressure kettle, pressure of the kettle reaches 2-10atm, and keeps 1-5 hours, then material is out, separated and washed. Comparing to existing preparation method, the material price is low and easy to get, reaction is simple, workshop operability is high, the whole yield and manufacture cost is low, so it is propitious to industrial manufacture. Computer by m-toluidine, the product mol yield can reach more than 90 percent of the theoretical value, if mother liquor is nest after reaction, the mol yield can reach more than 95 percent.