The present application relates to the technical field of biological detection pretreatment device, and more particularly to a
red blood cell folate pretreatment detection device, which comprises a magnetic stand, a
reaction tube is placed on the magnetic stand, and a multi-gear
magnetic separation mechanism for providing different
magnetic field strengths in the magnetic adsorption stage, the washing stage and the resuspension stage is arranged on the magnetic stand, and the multi-gear
magnetic separation mechanism comprises a lifting flat plate movably arranged in the magnetic stand. The lifting flat plate drives the cylindrical permanent
magnet to approach or move away from the bottom of the
reaction tube, and the three groups of rotating clamping blocks are matched to realize quick switching of gears. The strong
magnetic gear makes the permanent
magnet closely adhere to the bottom of the tube, and can quickly capture magnetic particles. The weak
magnetic gear makes the permanent
magnet maintain a proper distance, which can not only maintain adsorption but also avoid the agglomeration of magnetic beads. The zero
magnetic gear makes the
magnetic field basically disappear, which is convenient for resuspension. The three gears correspond to the core steps of pretreatment respectively, and the whole process is completed by one
machine, so that the sample does not need to be transferred between different devices, and the detection efficiency and
repeatability are effectively improved.