3DP technology realizing hierarchical compositing of multi-materials through single nozzle and application thereof

A multi-material, single-nozzle technology, applied in the field of 3D printing and biomedical material molding, achieves the effects of low cost, sufficient mixing, good equipment compatibility and practicability

Pending Publication Date: 2017-07-18
成都百年贝雅医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, 3DP is in the aspect of living cell printing, and the traditional nozzle mode cannot complete this task

Method used

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  • 3DP technology realizing hierarchical compositing of multi-materials through single nozzle and application thereof
  • 3DP technology realizing hierarchical compositing of multi-materials through single nozzle and application thereof
  • 3DP technology realizing hierarchical compositing of multi-materials through single nozzle and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Choose a primary barrel with an inner diameter of ϕ25mm and a secondary barrel with an inner diameter of ϕ10mm to assemble the nozzle device. The diameters of the inner and outer material printing nozzles are 200μm and 400μm respectively, and the distance between the inner and outer nozzle ports is 8mm. According to the diagram figure 1 to assemble. Among them, the uniformly modulated bio-binder and nano-hydroxyapatite material are loaded in the secondary barrel (inside), and the uniformly modulated bio-binder and nano-tricalcium phosphate material are loaded in the primary barrel (outside). Hierarchical composite printing of dual-phase materials. The porous bone-like scaffold product is printed, and the printed scaffold is sintered at a high temperature of 1100°C to obtain a bone tissue engineering scaffold with multiple biological functions. The hydroxyapatite material in the core of the composite scaffold has higher mechanical strength and good biocompatibility; the...

Embodiment 2

[0031] Choose a primary barrel with an inner diameter of ϕ25mm and a secondary barrel with an inner diameter of ϕ10mm to assemble the nozzle device. The diameters of the inner and outer material printing nozzles are 200μm and 400μm respectively, and the distance between the inner and outer nozzle ports is 8mm. According to the diagram figure 1 to assemble. Among them, the uniformly modulated and uniform bio-binder and nano-Al are loaded in the secondary barrel (inside) 3 o 2 For powder materials, the first-stage barrel (outside) is loaded with uniformly modulated bio-binder and nano-tricalcium phosphate materials for hierarchical composite printing of dual-phase materials. The porous bone-like scaffold product is printed, and the printed scaffold is sintered at a high temperature of 1100°C to obtain a bone tissue engineering scaffold with multiple biological functional benefits. Composite scaffold core nano-Al 3 o 2The powder has excellent mechanical strength and biologica...

Embodiment 3

[0033] Using nano-zirconia powder with a particle diameter of 50-80nm and nano-biphasic calcium phosphate powder as raw materials, the raw material preparation and printing nozzle assembly process are the same as in Example 1, except that the printing materials loaded in the inner and outer barrels are different. , that is, a uniformly modulated bio-binder and nano-zirconia powder are loaded in the secondary barrel (inside), and a uniformly modulated bio-binder and nano-biphasic calcium phosphate powder are loaded in the primary barrel (outside). , the bone tissue engineering scaffolds prepared by printing have both good mechanical properties and osteogenic inductivity, and can be applied to the repair of defective bone tissue in bearing parts.

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Abstract

The invention relates to a three-dimensional printing technology, and particularly relates to a 3DP technology realizing hierarchical compositing of multi-materials by using a single nozzle and an application thereof. According to the 3DP technology by using the single nozzle, on the basis of not changing an original three-dimensional printing technology equipment platform and on the premise of not changing an original movement mode and a control software of the printing equipment, the effect that different printing materials are continuously mixed, extruded and printed can be accurately realized through a first-stage printing material cylinder and a second-stage printing material cylinder which are designed to be arranged and a second-stage linkage piston device of a printing nozzle. According to the multi-material compositing printing nozzle, various printing materials can be fully composited, different materials are mixed sufficiently, and the composite effect is good; and the printing structure is a hierarchical wrapping and continuous compositing structure, and the 3DP technology has good equipment compatibility and feasibility, and has a wide application prospect in the field of biomedicine.

Description

technical field [0001] The invention belongs to the technical field of 3D printing, relates to the field of forming biomedical materials, in particular to a 3DP technology for realizing multi-material hierarchical compounding with a single nozzle and its application. Background technique [0002] Additive manufacturing technology (also known as 3D printing technology) is a material forming manufacturing technology that has developed rapidly in the past 20 years following the traditional cutting and cutting technology. Unlike traditional material removal processing methods, 3D printing is based on three-dimensional The digital model uses the superposition method of points, lines, surfaces, and volumes to flexibly manufacture parts with arbitrary complex shapes through layer-by-layer superimposition. 3D printing technology covers "Rapid Prototyping" at the front end of the product life cycle to "Rapid Manufacturing" in the full production cycle, as well as all other related ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B29C64/165B29C64/209B33Y30/00A61L27/40A61L27/12A61L27/54A61L27/50A61L27/56A61L27/02A61L27/38A61L27/52A61L27/22B29L31/00
CPCA61L27/025A61L27/12A61L27/222A61L27/3817A61L27/3821A61L27/50A61L27/52A61L27/54A61L27/56C08L89/00B33Y30/00B29L2031/7532A61L2430/02A61L2430/34A61L2300/412A61L2300/112
Inventor 周长春樊渝江张勃庆裴玄孙勇陈宇宋平张晖殷国富张兴栋
Owner 成都百年贝雅医疗科技有限公司
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