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An ointment that promotes regeneration of skin tissue

A technology of tissue regeneration and ointment, which is applied in skin diseases, drug combinations, and pharmaceutical formulas, and can solve problems such as long treatment cycles

Active Publication Date: 2021-03-23
重庆玛恩生物技术研究院有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The inventor used the technology disclosed in CN1902307B to treat depressed scars, and found that the treatment cycle was longer

Method used

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  • An ointment that promotes regeneration of skin tissue
  • An ointment that promotes regeneration of skin tissue
  • An ointment that promotes regeneration of skin tissue

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] A kind of ointment that promotes the regeneration of skin tissue, it consists of platelet-rich plasma 2ml (drawing the patient's venous blood 20 ml, platelet-rich plasma was obtained after twice centrifugation, and its platelet concentration was 1×10 15per L), thrombin 0.1mg, royal jelly 4g, glutathione 0.08mg, vitamin 1.3mg (vitamin A is 0.025mg, vitamin B1 is 0.025mg, vitamin C is 1mg, vitamin E is 0.25mg), collagen Peptide 12mg (hydroxyproline 5mg, proline 5mg, glycine 2mg), adenosine 0.8mg, guanine nucleotide 0.8mg, uracil nucleotide 0.8mg, thymine nucleotide 0.8mg, cytidine 0.8mg calcium chloride, 0.08mg calcium chloride, 0.15mg chitosan, 3mg gelatin, 4mg glycerin, 0.8mg coenzyme, 0.2mg potassium chloride, 0.3mg magnesium sulfate, 0.2mg zinc oxide, and 25ml distilled water.

[0029] In order to draw the curative effect of the ointment that promotes skin tissue regeneration of the present invention, the inventor has carried out following research to it:

[0030] P...

Embodiment 2

[0045] An ointment for promoting skin tissue regeneration, which consists of 2ml of platelet-rich plasma (take 24ml of patient's venous blood, obtain platelet-rich plasma after twice centrifugation, and its platelet concentration is 1.2×10 15 per L), thrombin 0.1mg, royal jelly 3g, glutathione 0.08mg, vitamin 1.3mg (vitamin A is 0.025mg, vitamin B1 is 0.025mg, vitamin C is 1mg, vitamin E is 0.25mg), collagen Peptide 12mg (hydroxyproline 5mg, proline 5mg, glycine 2mg), uracil nucleotide 4mg, chitosan 0.15mg, gelatin 3mg, glycerin 4mg, potassium chloride 0.25mg, magnesium sulfate 0.2mg, zinc oxide 0.15mg mixed with 25ml distilled water.

Embodiment 3

[0047] An ointment for promoting skin tissue regeneration, which consists of 2ml of platelet-rich plasma (18ml of venous blood from the patient is extracted, and platelet-rich plasma is obtained after twice centrifugation, and the platelet concentration is 1×10 15 per L), thrombin 0.08mg, royal jelly 5g, glutathione 0.05mg, vitamin A 0.05mg, collagen peptide 10mg (hydroxyproline 5mg, proline 5mg), uracil nucleotide 2mg, Calcium chloride 0.08mg, chitosan 0.15mg, gelatin 3mg, glycerin 4mg, coenzyme 0.5mg, potassium chloride 0.1mg, magnesium sulfate 0.1mg, zinc oxide 0.1mg and distilled water 25ml are mixed.

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Abstract

The invention provides an ointment for promoting skin tissue regeneration. The ointment is prepared by mixing 2 ml of platelet rich plasma (the blood platelet concentration is 0.9-1.4*1015 / L), 0.01-0.15 mg of thrombin, 2-5 g of royal jelly, 0.03-0.12 mg of glutathione, 0.001-3 mg of vitamins, 5-25 mg of collagen peptide, 0.01-7.5 mg of nucleotide, 0. 03-0.5 mg of calcium chloride, 0.1-0.3 mg of chitosan, 2-5 mg of gelatin, 3-10 mg of glycerin, 0.1-2 mg of coenzyme, 0.01-0.4 mg of potassium chloride, 0.04-0.6 mg of magnesium sulfate, 0.03-0.5 mg of zinc oxide and 10-50 ml of distilled water. The ointment for promoting skin tissue regeneration can promote regeneration of depression scar skin tissue of the human body, is suitable for adjuvant treatment of depression scars and especially has the remarkable treating effect on depression scar wounds having the depth (5-15mm), meanwhile a treatment period can be shortened, and the treating period can be shortened to 25 days for depression scars having the depth of 5mm or below.

Description

technical field [0001] The invention relates to an ointment for promoting the regeneration of skin tissue, in particular for promoting the regeneration of skin tissue at the wound after the operation of depressed scars in human body. Background technique [0002] Depressed scars, also known as depressed scars, refer to depressed scars caused by skin tissue defects, usually due to acne, surgery, trauma infection, chickenpox, smallpox and other diseases that cause skin collagen and elastin loss, and leave Permanent sunken scars. [0003] At present, the drugs that promote the regeneration of sunken scar skin tissue include fruit acids, the main components of which are grape acid, malic acid, citrus acid and lactic acid. The use of high concentrations of fruit acids can improve scars by promoting the proliferation of elastic fibers in the dermis. In addition, by extracting autologous fat cells and growth factors and injecting them three-dimensionally into the sunken part, it c...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K38/48A61K9/06A61K47/36A61K47/42A61K47/02A61P17/02A61K35/16A61K35/644A61K38/06A61K31/07A61K31/51A61K31/375A61K31/355A61K31/401A61K31/198A61K31/7076A61K31/708A61K31/7072A61K31/7068
CPCA61K9/0014A61K9/06A61K31/07A61K31/198A61K31/355A61K31/375A61K31/401A61K31/51A61K31/7068A61K31/7072A61K31/7076A61K31/708A61K35/16A61K35/644A61K38/06A61K38/4833A61K47/02A61K47/36A61K47/42C12Y304/21005A61K2300/00
Inventor 周欢
Owner 重庆玛恩生物技术研究院有限公司
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