218 results about "Carcainium Chloride" patented technology

The invention relates to a whitening composition containing pH-sensitive oxidized resveratrol hydrogel and application. The whitening composition is a composition of oxidized resveratrol hydrogel, a hydrolyzed opuntia pear flower extract and a mexican agastache rugosus flower / leaf / stem extract in a weight ratio of 1: (0.6-0.7): (0.01-0.02). The oxidized resveratrol hydrogel is prepared from the following raw materials in percentage by weight: 1 to 3 percent of oxidized resveratrol, 1 to 3 percent of 3-o-ethyl ascorbic acid, 15 to 20 percent of butanediol, 0.1 to 0.5 percent of sodium alginate, 0.1 to 0.5 percent of carboxymethylcellulose, 0.3 to 0.8 percent of calcium chloride and the balance of water. The three components of the whitening skincare product have a remarkable synergistic effect in the whitening aspect, the skin color can be jointly improved from different mechanisms, and meanwhile, the mildness and the safety are considered.

The invention discloses a high-temperature-resistant low-damage high-density solid-free well killing fluid which comprises 50-80 parts of water, 10-40 parts of calcium chloride, 10-40 parts of calcium bromide, 0.5-2 parts of a temperature-resistant tackifier, 1-3 parts of a temperature-resistant filtrate reducer, 0.5-2 parts of a high-temperature stabilizer, 0.5-3 parts of a high-temperature corrosion inhibitor, 0.5-2 parts of a salt crystallization inhibitor and 0.1-1 part of a waterproof locking agent. The technical problems that the saline water base fluid is unstable in density in a high-temperature environment, a reservoir is damaged, and a shaft is corroded are solved. The invention also discloses a preparation method of the high-temperature-resistant low-damage high-density solid-free kill fluid, which comprises the following steps: adding the water into a stirring kettle, then adding the calcium chloride, the temperature-resistant filtrate reducer, the temperature-resistant tackifier and the high-temperature corrosion inhibitor, uniformly stirring, and supplementing the calcium bromide during stirring to obtain a mixture; a salt crystallization inhibitor is injected into the stirring kettle, meanwhile, a high-temperature stabilizer is added, the stirring kettle is heated for full stirring, and the well killing fluid is obtained.

The invention discloses a high-expansion cellulose sponge with an arch-like structure as well as a preparation method and application of the high-expansion cellulose sponge. The method comprises the following steps: taking carboxymethyl cellulose and cellulose or micro-nano fibers thereof as raw materials, and adding a cross-linking agent to prepare the hydrogel. The preparation method comprises the following steps: preparing a hydrogel, then carrying out bidirectional freezing-freeze-drying on the hydrogel to obtain a sponge sample, soaking the sponge sample in a solution capable of reacting with carboxyl, the solution comprising at least one of a calcium chloride solution, a chitosan solution or a mixed solution of the calcium chloride solution and the chitosan solution, and finally carrying out secondary freeze-drying to obtain the sponge. The sponge is good in biocompatibility and high in liquid absorption rate, and the volume expansion rate can reach 10-15 times; after being compressed, the bandage can be quickly expanded to block wounds and quickly stop bleeding when being applied to bleeding parts. An arch-like layer structure is arranged between layers of the sponge, so that high compression can be realized, and expansion supporting force as long as more than 4 hours can be provided. The sponge prepared by the invention can be used for deep bleeding, such as deep and narrow through wound bleeding, human body junction bleeding and the like.

The invention discloses an in-situ crosslinking-self-degradation high-strength gel temporary plugging agent and a preparation method thereof, and belongs to the technical field of oil-gas field development. The gel temporary plugging agent is prepared from the following substances in parts by weight: 0.33 to 2.33 parts of polyvinyl alcohol, 0.67 to 4.67 parts of corn amylopectin, 2.8 to 7.0 parts of acrylamide, 1.2 to 3.0 parts of N-vinyl pyrrolidone, 0.05 to 1.05 parts of a cross-linking agent, 0.001 to 0.06 part of an initiator, 0.3 to 2.1 parts of glycerol, 0.02 to 0.14 part of calcium chloride and the balance of water, and the sum of the parts by weight of the substances is 100 parts. The preparation method is simple and convenient to operate, raw materials are low in price and easy to obtain, the preparation process is controllable, and huge industrial popularization prospects are shown. The gel temporary plugging agent is used for a reservoir temporary plugging steering process, can be self-degraded under the condition of constant temperature of a stratum, and has important significance for realizing efficient development of an oil field and improving the oil and gas recovery ratio.

The invention discloses a structure-reversible intervariant metal frame adsorption material and a preparation method and application thereof, and belongs to the technical field of adsorption materials, and the preparation method comprises the following steps: dissolving anhydrous calcium chloride and 2, 5-pyrazine dicarboxylic acid in a mixed solvent, then adding concentrated nitric acid, carrying out a heating reaction, continuing to activate the obtained solid product at 50-420 DEG C for 24 h, filtering, washing, and drying to obtain the structure-reversible intervariant metal frame adsorption material. And realizing structural transformation to obtain the intervariant metal frame adsorption material with the reversible structure. The reversible intervariant metal framework provided by the invention provides a new strategy for research and development of multifunctional MOFs materials, so that the material can adjust the pore characteristics and the three-dimensional space structure according to the temperature change, and the macroscopic adsorption performance is obviously influenced. The preparation process provided by the invention is simple and convenient, and a new strategy is provided for cadmium ion sewage treatment.

Compositions and methods for cleansing the eyelid and treating an ocular condition with an ophthalmic composition consisting essentially of water, PEG-80 sorbitan laurate, methyl gluceth-20, PEG-120 methyl glucose dioleate, phytosphingosine HCl, decyl glucoside, 1,2-hexanediol, caprylyl glycol, disodium cocoamphodiacetate, panthenol, polyaminopropyl biguanide, sodium chloride, potassium chloride and calcium chloride.

The invention relates to the technical field of biomedical materials, and provides a preparation method and application of cross-linked carboxymethyl cellulose. The preparation method comprises the following steps: S1, dissolving anhydrous calcium chloride in absolute ethyl alcohol, sterilizing and filtering to obtain a sterile calcium chloride solution; s2, adding the dehydrated and purified sodium carboxymethyl cellulose into a sterile calcium chloride solution, and stirring for reaction; s3, after the reaction is finished, suction filtration is performed, filter residues are collected and washed, residual calcium chloride is removed, then vacuum drying is performed, and cross-linked carboxymethyl cellulose is obtained. The cross-linked carboxymethyl cellulose and sodium carboxymethyl cellulose have high consistency in chemical activity, physiological and biochemical activity, biocompatibility and safety risk, but in physical performance, the cross-linked carboxymethyl cellulose is hydrogel fiber, is insoluble in water, can more remarkably maintain the volume of a filling part, and is longer in duration time, so that the cross-linked carboxymethyl cellulose is more stable in filling. And the effects of instant filling and long-acting filling of the microsphere-containing surface filling agent are realized.

The invention provides a pharmaceutical composition, glycyrrhizic acid and polymyxin B self-assembled carrier-free hydrogel as well as a preparation method and application thereof, and belongs to the technical field of biological medicines. The invention provides a pharmaceutical composition. The pharmaceutical composition comprises glycyrrhizic acid and polymyxin B. According to the pharmaceutical composition, the inhibition effect on MRSA is enhanced through drug combination, the use of polymyxin B is reduced through the synergistic effect, and the development pressure of antibiotic drug resistance is relieved. According to the hydrogel formed by crosslinking the glycyrrhizic acid and the calcium chloride, the glycyrrhizic acid and the calcium chloride are crosslinked to form the hydrogel, and the calcium chloride is introduced into a glycyrrhizic acid system to increase the mechanical strength of the glycyrrhizic acid hydrogel, so that the glycyrrhizic acid hydrogel can be better attached to a wound. The invention provides a glycyrrhizic acid and polymyxin B self-assembled carrier-free hydrogel and a preparation method of the glycyrrhizic acid and polymyxin B self-assembled carrier-free hydrogel. The hydrogel does not contain any inert carrier component at all, the drug loading rate of 100% is achieved, and adverse reactions possibly caused by a traditional carrier system are effectively avoided.

The invention relates to a compound biocontrol bacterium immobilized microsphere as well as a preparation method and application thereof, and belongs to the technical field of biocontrol. In order to solve the problem of lack of compound biocontrol bacteria and an effective immobilization method in the prior art, the invention provides a compound biocontrol bacteria immobilized microsphere, which is formed by embedding compound biocontrol bacteria in sodium alginate-calcium chloride, and the compound biocontrol bacteria comprise bacillus velezensis and spiropolyspora pink. The bacillus velezensis and the spiropolyspora pink have an excellent inhibition effect on botrytis cinerea after being compounded, and the compound bacterial liquid is immobilized in the calcium alginate microspheres by virtue of an immobilization technology, so that the activity of microorganisms can be more effectively maintained, and the stability and the effect of biological control are remarkably improved. According to the invention, the compounding proportion and the immobilization preparation process of the biocontrol bacteria are optimized, so that the antibacterial effect of the compounded biocontrol bacteria immobilized microspheres reaches 76.19%, which is superior to that of a compounded microbial inoculum and a traditional chemical pesticide.

The invention relates to the technical field of biological materials, in particular to a PDRN porous microsphere as well as a preparation method and application thereof. The PDRN porous microspheres are prepared from the following raw materials: PDRN, an oil phase matrix, a curing agent and metal salt, the curing agent is at least one of polyethylene glycol acrylate and polylysine; the metal salt is at least one of calcium chloride, zinc chloride, magnesium chloride and ferric chloride. The PDRN porous microsphere has the advantages of being controllable in size, excellent in disintegration resistance and excellent in swelling resistance, is high in moist heat sterilization tolerance and strength, can be used as a filling material for medical beauty or an ideal candidate material of a tissue engineering scaffold, and has potential application value.

The invention discloses a composite inducer for promoting adhesion and metamorphosis of marine bivalve mollusk larvae and an application method of the composite inducer. The composite inducer for promoting adhesion and metamorphosis of the marine bivalve mollusk larvae comprises glutamine, glutamic acid, potassium chloride, calcium chloride and taurine, and the concentration ratio of the glutamine to the glutamic acid to the potassium chloride to the calcium chloride to the taurine is 1: 1: 2 * 10: 1.7 * 10: 4. According to the application, glutamine, potassium ions, calcium ions, glutamic acid and taurine are matched, the application effect of the glutamine, the potassium ions, the calcium ions, the glutamic acid and the taurine in the aspect of improving the attachment and metamorphosis rate of the shellfish larvae is defined, the technical blank of multi-component cooperative regulation and control of the attachment and metamorphosis of the shellfish at present is filled, a new solution is provided for bivalve shellfish fry production, and the application prospect is wide. The method is of great significance in promoting healthy development of the mariculture industry.

The invention belongs to the technical field of biological agents and bioremediation, and particularly relates to a PAHs degrading strain as well as a fungicide and application thereof. The invention provides a strain for degrading PAHs (polycyclic aromatic hydrocarbons), the strain is Brucella anthrapi M1, and the preservation number of the strain is CCTCC (China Center for Type Culture Collection) M 2024922. The strain M1 can grow and breed by taking benzo (a) pyrene (BaP), pyrene or phenol as the unique carbon source and energy, and can quickly degrade PAHs; the strain is cultured in an inorganic salt culture medium with BaP, pyrene and phenol initial concentration of 5 mg / L for 5 days, and the degradation efficiency reaches 81%, 37% and 28% respectively. The bacterial strain is prepared into a microbial inoculum through crosslinking of sodium alginate and calcium chloride, and the degradation efficiencies of the microbial inoculum to BaP, pyrene or phenol respectively reach 46%, 37% and 80%. After the bacterial strain is prepared into a bacterial agent, the BaP degradation efficiency of the bacterial agent can reach 80%. Therefore, the strain and the fungicide thereof have a good application prospect in the bioremediation of PAHs (especially BaP) polluted soil or water.

The invention discloses a preparation process of a nano calcium nutrient, and relates to the technical field of nutrients. The preparation process comprises the following steps: S1, filling two cationic resin columns which are marked as a column 1 and a column 2, respectively soaking the column 1 and the column 2 in a saturated calcium chloride solution, washing the column 1 and the column 2 with the saturated calcium chloride solution until the pH value is 5-6, and washing the column 1 and the column 2 with purified water until the column 1 and the column 2 are neutral for later use; s2, adding a self-made milk hydrolyzed mixed amino acid sodium salt aqueous solution into the cationic resin column 1 prepared in the step S1 at normal temperature, slowly eluting and exchanging, and circularly exchanging the effluent for 3-5 times to obtain an effluent 1; s3, enabling the effluent 1 obtained in the step S2 to pass through a cationic resin column 2, and slowly eluting and exchanging to obtain effluent 2; and S4, carrying out vacuum decompression concentration on the effluent 2 obtained in the step S3, spraying the concentrated solution, feeding into a high-speed airflow chamber, further cutting the atomized solution by high-speed airflow, feeding into a freezing chamber, and freeze-drying to obtain the product. The nano mixed amino acid chelated calcium provided by the invention is small in toxic and side effects and good in safety.

The invention provides a preparation for blood purification and a preparation method and application thereof.The preparation is in a solid state or a liquid state, L-malic acid serves as a pH regulator of the preparation, calcium citrate and calcium chloride are used for providing total calcium, the total calcium addition value of the preparation is 1.0-1.5 mmol / L, and the total calcium addition value of the preparation is 1.0-1.5 mmol / L. A dialysate for clinical application of the preparation contains ionized calcium and molecular calcium at the same time, the molar concentration ratio of the ionized calcium to the molecular calcium is 2-6, the ratio of the total calcium addition value to the molar concentration of the citrate radical is 10-12, the molar concentration ratio of the citrate radical to the L-malic acid is 0.05-0.15, and the molar concentration ratio of the citric acid radical to the L-malic acid is 0.05-0.15. The calcium chloride, the calcium citrate and the L-malic acid are reasonably proportioned, so that the supply of 80-85% of effective free calcium can be realized on the premise of ensuring a low total calcium addition value, thereby obviously reducing adverse reactions caused by low calcium or high calcium in the dialysis process, and effectively preventing and controlling dialysis syndromes and the problem of calcium ion disorder possibly occurring after dialysis.

The invention discloses a preparation method and application of two chemical crosslinking type injectable hemostatic sealant. According to the invention, four-arm polyethylene glycol succinimide glutaric acid ester (TPEG-SG) and carboxymethyl chitosan (CMCS) are taken as main materials, and calcium chloride is added or not added, so that two injectable hemostatic sealing adhesives with chemical crosslinking characteristics are designed and prepared. After the two kinds of sealant are injected to a bleeding part, rapid and efficient gelation and tissue adhesion can be achieved through chemical crosslinking of carboxyl activating groups of the four-arm polyethylene glycol succinimide glutaric acid ester, amino groups in carboxymethyl chitosan and amino groups on the surface of tissue, and therefore wounds are effectively sealed. Compared with a traditional hemostatic material, the two sealing glues have the characteristics of rapid in-situ wound formation, strong tissue adhesion, rapid hemostasis and the like, the problems of poor adhesion performance and poor hemostasis capability of a conventional hemostatic material are solved, and the hemostatic material is more suitable for hemostasis of non-compressible hemorrhage in a special wound environment and has good clinical and military application prospects.

The invention discloses a composition for treating intractable skin infection, sores and ulcers and inflammation as well as a preparation method and application of the composition, and belongs to the technical field of functional compositions. The composition is prepared from the following components in parts by mass: 1 to 5 parts of baicalin, 0.5 to 3 parts of antibacterial alkaloid, 2 to 6 parts of asiaticoside, 3 to 8 parts of salvianolic acid B, 1 to 4 parts of gallic acid, 5 to 10 parts of rhizoma bletillae polysaccharide, 3 to 10 parts of konjac glucomannan, 3 to 5 parts of chitosan, 8 to 20 parts of glycerol, 0.5 to 2 parts of genipin, 1 to 3 parts of calcium chloride, 1 to 3 parts of laurocapram and 40 to 80 parts of water. The antibacterial alkaloid comprises berberine or phellodendrine. Based on deep understanding of an intractable skin pathological mechanism, the components are scientifically matched, and the composition shows a remarkable synergistic effect in in-vitro antibacterial, anti-biofilm and anti-inflammatory experiments. The preparation process is simple, low in cost and suitable for industrial production.

The invention discloses a method for adjusting the pore opening degree of Shanghai green, and belongs to the technical field of plant detection. Shanghai leaves are placed in 20mL of open liquid containing (1) 0.5% potassium chloride and 100 [mu] M / L calcium chloride or (2) 0.5% potassium chloride and 50 [mu] M / L brassinolide or (3) 0.5% potassium chloride and 10 [mu] M / L cytokinin or (4) 0.5% potassium chloride and 5 [mu] M / L gibberellin or (5) 0.5% potassium chloride and 100 [mu] M / L methyl jasmonate, culture is performed under illumination, and the illumination time is set to be 5h, so that the pore opening degree of Shanghai is remarkably increased. Compared with a control group (containing 0.5% of potassium chloride), the pore openness of the treatment is respectively increased by 33.5%, 43.5%, 43.4%, 27.1% and 70.2%. The method disclosed by the invention lays a technical foundation for rapidly screening out the exogenous environmental stimulation factor (environical stimuli) capable of increasing the opening degree of the pore.

The invention belongs to the field of solid waste utilization, and particularly provides a Ca2PO4Cl decomposition and resource utilization method, which comprises the following steps: dispersing Ca2PO4Cl in an alcohol solvent, and carrying out solvothermal modification treatment to obtain a modified material; carrying out protonation treatment on the modified material in a separation liquid containing an imgabs0 # auxiliary agent in a formula 1 # and hydrochloric acid, and decomposing to obtain a treatment product of phosphoric acid and calcium chloride; and separating to obtain calcium chloride and phosphoric acid. The method for decomposition and resource utilization of Ca2PO4Cl still belongs to the industry blank, and in order to fill the technical blank, the innovative research shows that Ca2PO4Cl is subjected to solvothermal modification transformation in alcohol in advance, and then ion exchange is performed in a hydrochloric acid solution containing a formula 1, so that decomposition of Ca2PO4Cl can be realized, and calcium chloride and phosphoric acid are formed.

The invention discloses a water body composite phosphorus locking agent and a preparation method thereof, and belongs to the technical field of water quality treatment. The composite phosphorus locking agent for the water body comprises the following raw material components in parts by weight: 0.5-1.5 parts by mass of modified zirconium hydroxide, 4 parts by mass of sodium alginate, 2.3-2.5 parts by mass of a composite organic material, 6 parts by mass of calcium chloride and 1-3 parts by mass of ferric trichloride, the modified zirconium hydroxide is obtained by modifying zirconium hydroxide with epoxy chloropropane; the composite organic material is prepared from diethanol amine and chitosan; the water body composite phosphorus locking agent prepared by the method is relatively high in phosphorus removal rate.

The invention discloses a composition for relieving, repairing and promoting skin regeneration as well as a preparation method and application of the composition. The composition is prepared from the following raw materials in parts by weight: 0.1 to 5 parts of mandelic acid, 0.5 to 10 parts of a cynanchum atratum extract, 1 to 8 parts of a xylitol compound, 0.5 to 15 parts of regenerated silicon, 1 to 10 parts of a starfish regeneration repair factor, 0.3 to 1.5 parts of trimethylolpropane tri (3-mercaptopropionic acid) ester, 0.05 to 0.5 part of calcium chloride, 0.1 to 1 part of an additive, 0.2 to 2 parts of chitosan-polycaprolactone, 0.2 to 1 part of a pH regulator and 5 to 15 parts of a solvent. 0.3 to 0.8 part of an antioxidant and 3 to 10 parts of a humectant; the additive is hyaluronic acid or formylated hyaluronic acid. Through a multi-channel synergistic effect, the effects of relieving, repairing and promoting skin regeneration are improved.

The present application relates to the technical field of oil and gas production, and specifically discloses a drilling fluid and a preparation method thereof. A drilling fluid, the raw materials of which include: 30-50 parts of coconut oil heptyl ester derivative; 20-30 parts of glyceryl stearate; 20-30 parts of capric triglyceride; 15-20 parts of octadecyl paraben; 10-20 parts of polystyrene-coated paraffin microcapsules; 5-10 parts of calcium chloride; 1-5 parts of emulsifier; 1-5 parts of lightener; 1-5 parts of fluid loss reducer; 10-20 parts of water. The drilling fluid of the present application has strong low temperature resistance and good rheology, and is suitable for oil and gas drilling work under low temperature conditions.

The invention relates to a calcium chloride injection and a production method thereof, and relates to the technical field of calcium chloride injection production, a solvent of the calcium chloride is water for injection, and the injection contains the following components: 80-120 g / L of calcium chloride; the concentration of the water for injection is 800-1200 g / L; hydrochloric acid is a proper amount of component for adjusting the pH value to 5.3-5.8; and the sodium hydroxide is a proper amount of component used for adjusting the pH value to 5.3-5.8. According to the calcium chloride injection and the production method thereof, the problems of solution turbidity, calcium ion precipitation, oxidative degradation and the like caused by insufficient dissolution and local supersaturation of calcium chloride in the prior art are effectively solved by accurately controlling the concentration of calcium chloride and adopting a nitrogen protection dissolution process. Meanwhile, a 0.22 mu m polyethersulfone two-stage filter element series connection filtering process, an integrity testing process with the foaming point larger than or equal to 3450 kPa and a sterilization and leak detection integrated process are adopted, the sterility guarantee level and stability of the product are remarkably improved, the endotoxin of the finished product is smaller than 0.5 EU / mL, the number of visible foreign matter larger than or equal to 10 mu m is reduced by larger than or equal to 60%, and the clinical safety and effectiveness of the injection are ensured.

The invention discloses a cell protection solution for venous transfusion as well as a preparation method and application of the cell protection solution. The cell protection liquid comprises 4 to 8 mg / ml of sodium chloride, 0.1 to 0.5 mg / ml of potassium chloride, 2.8 to 3.5 mg / ml of sodium lactate, 0.1 to 0.3 mg / ml of calcium chloride, 0.15 to 0.3 [mu] g / ml of glucose, 0.01 to 0.03 ml / ml of 20% human serum albumin, 4 to 8 [mu] g / ml of vitamin E, 0.2 to 2 [mu] g / ml of vitamin B12, 0.5 to 2 [mu] g / ml of folic acid, 4 to 8 [mu] g / ml of L-aspartic acid and 0.5 to 2 [mu] g / ml of glutathione. The cell preserving fluid provided by the invention can effectively protect cells for a long time, can be directly transfused back through veins, does not need special treatment, is convenient for clinical application, and has better application prospect and development potential in the development of the clinical treatment of the cells towards the drug direction.

The invention provides a fosfomycin calcium salt preparation process, and particularly relates to the field of medicines. The preparation method comprises the following steps: mixing water and ethanol to obtain a mixed solution, adding 200-220g of a fosfomycin intermediate into the mixed solution, adding 3-4g of talcum powder, heating to 80-85 DEG C, filtering to obtain a filter cake, washing the filter cake by using 20mL of ice ethanol, heating to 85 DEG C, and drying for 2 hours to obtain DL-salt; uniformly mixing 20-25g of sodium hydroxide and 70mL of purified water, adding 65-70g of DL-salt, heating to 60 DEG C, uniformly mixing, cooling to 45-50 DEG C, and standing for 1.5-2 hours to obtain a lower-layer separation solution; the preparation method comprises the following steps: uniformly mixing 35-40g of calcium chloride and 100mL of purified water, adding 3-4g of talcum powder, standing for 30 minutes, filtering, and adjusting the pH value to 4.8-5 to obtain a calcium chloride solution; and adding 600-650ml of purified water into the lower-layer separation liquid, heating to 65-70 DEG C, adding a calcium chloride solution, filtering, washing with distilled water until no washing liquid drips, and drying at 60-65 DEG C for 1 hour to obtain a finished product. The method is high in yield, simple in step and beneficial to improvement of production efficiency and reduction of production cost.

The invention discloses a method for enhancing adhesion ability of coral larvae after enhancement and release. According to the method, coral larvae (such as coral plankton larvae) are exposed to a 40 mM calcium chloride (CaCl2) solution to be treated for 12-24 hours, and then enhancement and release are carried out. The treated larvae show remarkably enhanced adhesion ability after releasing, the accumulated adhesion rate within 3 days reaches 66.33% and is increased by 240% compared with that of a control group in the same period, and the average survival rate reaches 98.14%. Meanwhile, the transverse growth area and the budding number of attached larvae are remarkably increased, and the density of zooxanthellae, the photosynthetic efficiency and the chlorophyll content have no negative effects. The CaCl2 solution is used for successfully inducing the continuous attachment effect of the coral larvae, the method is easy and convenient to operate, low in cost and environmentally friendly, the attachment success rate of enhancement and release of the coral larvae and the subsequent growth performance of the larvae are remarkably increased, and the method is suitable for repairing and protecting a coral reef ecological system.

This invention relates to the field of biomaterial preparation technology, and in particular to a morphology-controllable mesoporous hydroxyapatite nanosphere, its preparation method, and its applications. The preparation method includes: S1, mixing an aqueous solution of pyridoxal phosphate with an aqueous solution of calcium chloride, adjusting the pH of the mixed solution to 7-11 to obtain a precursor solution; S2, placing the precursor solution in a microwave reactor for reaction to obtain mesoporous hydroxyapatite nanospheres. The preparation method provided by this invention is simple, the reaction conditions are easily controlled, and it is highly safe and reliable. It enables precise control of the morphology and particle size of the hydroxyapatite microspheres, and the prepared product exhibits excellent biocompatibility and structural regularity. It has good industrial application prospects in the field of biomedical implants such as bone tissue repair and is suitable for large-scale production.

The invention relates to a magnesium- aluminium layered double hydroxide (Mg-Al LDH) based filler product comprising boron and functionalised with phosphocholine chloride calcium salt tetrahydrate (PC), the synthesis method of this filler product, and obtaining a new material by preparing a composite material of this filler product, which has antibacterial activity, with a thermoplastic polymer or thermosetting polymer. In the production of the composite material that is the subject of the invention, as the polymer, preferably unsaturated polyester resin (DPes) is used. The composite material comprising the filler product of the invention has the feature of preventing bacterial adhesion / biofilm formation. Said material has the potential to be used for various applications, including medical devices, industrial processes, food production, storage and sales areas, food contact surfaces, areas requiring cleaning and hygiene, and different surface materials.

The invention belongs to the technical field of medicine preparation, and particularly relates to a fenoprofen calcium preparation method which comprises the following steps: 1) m-hydroxyacetophenone and bromobenzene generate an intermediate 1, namely m-phenoxyacetophenone under the action of alkali and cuprous iodide; 2) reacting the intermediate 1 with ethyl chloroacetate under the action of strong base, and then performing hydrolysis and decarboxylation reaction to generate an intermediate 2, namely 2-(3-phenoxy phenyl) propionaldehyde; the invention discloses a preparation method of fenoprofen calcium, which comprises the following steps: (1) preparing fenoprofen, (2) preparing fenoprofen, (3) carrying out oxidation reaction on an intermediate 2 to obtain fenoprofen, (4) reacting fenoprofen with a sodium hydroxide solution to obtain fenoprofen sodium, and (5) salifying fenoprofen sodium with a calcium chloride solution to obtain fenoprofen calcium.

This invention discloses a biological reinforcement and corrosion protection process for bridge pier cracks, comprising: S1, extracting calcium ions from South China Sea calcareous sand to obtain a calcium chloride solution; S2, installing a reaction sleeve mold reaction device at the location of the cracked bridge pier, filling the gap between the bridge pier and the mold reaction device with South China Sea calcareous sand particles in three batches, and injecting bacterial solution, urea, and the calcium chloride solution obtained in step S1 in batches for cyclic infusion, and repeating the cyclic infusion process. This invention, by using the calcium chloride solution extracted from South China Sea calcareous sand and the bacterial solution for cyclic infusion, can achieve biological reinforcement of bridge pier cracks, resulting in better compatibility and permeability with the bridge pier substrate material. It can penetrate even the smallest cracks, and the generated calcium carbonate crystals can effectively and better bond with the bridge pier substrate material, playing a role in filling and bonding cracks. It also has the advantages of low cost, convenient material sourcing, few and safe byproducts, and no pollution to the marine environment.

The invention discloses haemostatic and anti-infection bifunctional algal glue and a preparation method thereof. The phycocolloid is prepared from phycocyanin, sodium alginate, polydopamine-piperidine nanoparticles, calcium chloride and water / ethanol. The preparation method comprises the following steps: reacting 2, 2, 6, 6-tetramethylpiperidine oxide with dopamine hydrochloride to prepare polydopamine-piperidine nanoparticles; the preparation method comprises the following steps: fully dissolving phycocyanin, sodium alginate and polydopamine-piperidine nanoparticles in a water / ethanol mixed solution; and adding an isometric calcium chloride aqueous solution, and stirring at room temperature to prepare the haemostatic and anti-infection bifunctional algal glue. The ratio of phycocyanin to sodium alginate is adjusted, the phycocyanin accounts for 1%-10% by weight, the sodium alginate accounts for 1%-5% by weight, different rheological properties and shape maintenance properties are obtained, the content of the nano polydopamine-piperidine compound is adjusted, the weight fraction is 0.1%-0.5%, the photo-thermal sterilization performance is obtained, and the photo-thermal sterilization effect is good. Therefore, the problem of repeated wound infection can be solved only through illumination.