A self-assembled multi-pulse release method for fat-soluble drugs

A fat-soluble drug, multi-pulse technology, applied in pharmaceutical formulations, organic active ingredients, medical preparations with non-active ingredients, etc. Increase fixing performance, wide application range and obvious effect
CN107050466BActive Publication Date: 2020-06-30SOUTHEAST UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SOUTHEAST UNIV
Publication Date
2020-06-30

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Abstract

The invention discloses a self-assembled multi-pulse release method for lipid-soluble medicines. The self-assembled multi-pulse release method comprises the following steps: firstly, preparing nano capsules with the lipid-soluble medicines, and uniformly mixing the nano capsules with a gelatigenous medium material; and in the mixed medium of the nano capsules and the medium materials, building Liesegang ring patterns, and generating periodic sediment crystals. The self-assembled multi-pulse release method is wide in application range, the stability of medicines and fixation properties of the medicines in medium systems are improved, and a very good release control function is achieved.
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Description

technical field

[0001] The invention belongs to the field of pharmaceutical preparations and relates to a self-assembled multi-pulse release method for fat-soluble drugs. Background technique

[0002] The sustained release of drugs has always been one of the key topics studied by scientists. Sustained release of drugs is to delay the release, absorption, distribution, metabolism and excretion of drugs in the body by appropriate methods, so as to prolong the drug effect. A dosage form that keeps the blood drug concentration constant so that it can better exert its curative effect.

[0003] Polymer materials are widely used in the field of drug sustained release, and drug sustained release materials refer to a class of polymer materials that can delay drug release for more than 8 hours. It is the current research focus in the field of pharmacy, and it is also one of the important directions of research in chemistry, biology, and materials science. Some macromolecular materi...

Claims

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